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Information on EC 6.2.1.1 - acetate-CoA ligase

for references in articles please use BRENDA:EC6.2.1.1

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IUBMB Comments

Also acts on propanoate and propenoate.

The enzyme appears in viruses and cellular organisms
Reaction Schemes
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ATP
+
acetate
+
CoA
=
AMP
+
diphosphate
+
acetyl-CoA
+
+
=
+
+

Synonyms
acyl-coa synthetase, acetyl-coa synthetase, acss2, acetyl-coa synthase, acetyl coa synthetase, acetyl-coenzyme a synthetase, codh/acs, acecs2, acetyl coenzyme a synthetase, seacs, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
acetate and ATP formation from acetyl-CoA III, acetate conversion to acetyl-CoA, adlupulone and adhumulone biosynthesis, chitin deacetylation, cis-geranyl-CoA degradation, colupulone and cohumulone biosynthesis, ethanol degradation II, ethanol degradation III, ethanol degradation IV, L-isoleucine biosynthesis V, lupulone and humulone biosynthesis, reductive glycine pathway of autotrophic CO2 fixation