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Literature summary for 6.2.1.1 extracted from
- The role of acetyl-coenzyme A synthetase in Arabidopsis (2008), Plant Physiol., 147, 1822-1829.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | a constructed acs1 knockout mutant has a disruption in the plastidic acetyl-CoA synthetase gene leading to 90% decreased ACS activity and largely blocked incorporation of exogenous 14C-acetate and 14C-ethanol into fatty acids. Whereas the disruption has no significant effect on the synthesis of bulk seed triacylglycerols, the acs1 plants are smaller and flowered later. The acs1 mutant shows increased sensitivity to exogenous acetate, ethanol, and acetaldehyde compared to wild-type plants, phenotype, overview | Arabidopsis thaliana |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Arabidopsis thaliana | 9507 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Arabidopsis thaliana |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate + CoA | Arabidopsis thaliana | - |
AMP + diphosphate + acetyl-CoA | - |
? | |
| additional information | Arabidopsis thaliana | role of ACS in destroying fermentative intermediates | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | B9DGD6 | gene acs1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + acetate + CoA | - |
Arabidopsis thaliana | AMP + diphosphate + acetyl-CoA | - |
? | |
| additional information | role of ACS in destroying fermentative intermediates | Arabidopsis thaliana | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Acetyl-CoA synthetase | - |
Arabidopsis thaliana |
| acetyl-coenzyme A synthetase | - |
Arabidopsis thaliana |
| ACS | - |
Arabidopsis thaliana |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Arabidopsis thaliana | |
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Release 2023.1 (January 2023)
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