EC Number   |
Natural Substrates |
|---|
    6.2.1.1 | ATP + acetate + CoA |
- |
| 6.2.1.1 | ATP + acetate + CoA |
enzyme is involved in pathway of acetate activation. Cells induce acs transcription, and thus the ability to assimilate acetate, in response to rising cAMP levels, falling oxygen partial pressure, and the flux of carbon through pathways associated with acetate metabolism |
| 6.2.1.1 | ATP + acetate + CoA |
lipogenic enzyme, gene is highly induced by SREBP-1a, SREBP-1c and SREBP-2. The enzyme might also play an important role in basic cellular energy metabolism |
| 6.2.1.1 | ATP + acetate + CoA |
no relationship between the enzyme level and the capacity of the plants to incorporate CO2 into labeled fatty acids. Very limited role of the enzyme in the biosynthesis of lipids |
| 6.2.1.1 | ATP + acetate + CoA |
the enzyme activates acetate so that it can be used for lipid synthesis or for energy generation. The acetyl-CoA synthetase mRNA, and hence the ability of cells to activate acetate, is regulated by sterol regulatory element-binding proteins in parallel with fatty acid synthesis in animal cells |
| 6.2.1.1 | ATP + acetate + CoA |
the bifunctional enzyme carbon monoxide dehydrogenase/acetyl-coenzyme A synthase is a key enzyme in the Wood-Ljungdahl pathway of carbon fixation |
| 6.2.1.1 | ATP + acetate + CoA |
AceCS2 is reversibly acetylated at Lys642 in the active site of the enzyme. A mammalian sirtuin directly controls the activity of a metabolic enzyme by means of reversible lysine acetylation |
| 6.2.1.1 | ATP + acetate + CoA |
acetate-CoA ligase is a key enzyme for conversion of acetate to acetyl-CoA |
| 6.2.1.1 | ATP + acetate + CoA |
acetyl-CoA synthetase from Pseudomonas putida U is the only acyl-CoA activating enzyme induced by acetate in this bacterium |
| 6.2.1.1 | ATP + acetate + CoA |
gene acs encoding the enzyme is regulated by quorum sensing, and acs regulation plays a role in symbiosis, overview |
