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BRENDA support

Ligand acetyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of acetyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C23H38N7O17P3S
acetyl-CoA
ZSLZBFCDCINBPY-ZSJPKINUSA-N
Synonyms:
ac-CoA, AcCoA, Acetyl-CoA derivates, acetyl-SCoA, acetyl Co-A, acetylCoA, acetyl CoA, acetylcoenzyme A, acetyl coenzyme A, S-acetyl-CoA
Pathway Source
Pathways
BRENDA
3-phenylpropionate degradation, acetate fermentation, acetoin degradation, acetyl CoA biosynthesis, aerobactin biosynthesis more
KEGG
Aflatoxin biosynthesis, Alcoholic liver disease, AMPK signaling pathway, Benzoate degradation, beta-Alanine metabolism more
MetaCyc
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase), (8E,10E)-dodeca-8,10-dienol biosynthesis, (aminomethyl)phosphonate degradation, (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered), (R)-camphor degradation more


Show all pahtways known for Show all BRENDA pathways known for acetyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1840 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA = acetoacetyl-CoA + CoA
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acetyl-CoA + NADH + H+ = acetaldehyde + CoA + NAD+
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acetyl-CoA + NADH + H+ = acetaldehyde + CoA + NAD+
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acetyl-CoA + NADH + H+ = acetaldehyde + CoA + NAD+
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acetyl-CoA + NADH + H+ = acetaldehyde + CoA + NAD+
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acetyl-CoA + dephospho-CoA = CoA + acetyl-dephospho-CoA
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[biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine + acetyl-CoA = [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine + malonyl-CoA
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acetyl-CoA + hydrogen sulfide = CoA + thioacetate
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acetyl-CoA + L-N6-hydroxylysine = CoA + N6-acetyl-N6-hydroxylysine
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acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate = CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate
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acetyl-CoA + thioethanolamine = CoA + S-acetylthioethanolamine
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acetyl-CoA + dolichol = CoA + dolichyl acetate
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acetyl-CoA + L-carnitine = CoA + acetyl-carnitine
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myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA
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acetyl-CoA + 16-epivellosimine = CoA + vinorine
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acetyl-CoA + 10-desacetyltaxuyunnanin C = CoA + taxuyunnanin C
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acetyl-CoA + 10-deacetylbaccatin III = CoA + baccatin III
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acetyl-CoA + corrinoid protein = CoA + CO + methylcorrinoid protein
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acetyl-CoA + deacetylcephalosporin C = CoA + cephalosporin C
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[elongator tRNAMet]-cytidine34 + ATP + acetyl-CoA = [elongator tRNAMet]-N4-acetylcytidine34 + ADP + phosphate + coenzyme A
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acetyl-CoA + imidazole = CoA + N-acetylimidazole
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acetyl-CoA + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate = CoA + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate
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acetyl-CoA + fumigaclavine B = CoA + fumigaclavine A
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acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose
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acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose
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2-acyl-sn-glycerol + acetyl-CoA = diacylglycerol + CoA
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acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose = CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose
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acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+ = 5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+
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acetyl-CoA + 5 malonyl-CoA + 2 NADPH + 2 H+ = 2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+
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acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O
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(5S)-5-amino-3-oxohexanoate + acetyl-CoA = L-3-aminobutanoyl-CoA + acetoacetate
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acetyl-CoA + an N-terminal-L-methionyl-[transmembrane protein] = an N-terminal-Nalpha-acetyl-L-methionyl-[transmembrane protein] + CoA
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acetyl-CoA + (3S)-3,6-diaminohexanoate = CoA + (3S)-6-acetamido-3-aminohexanoate
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acetyl-CoA + an N-terminal L-alanyl-[S5 protein of 30S ribosome] = CoA + an N-terminal N-acetyl-L-alanyl-[S5 protein of 30S ribosome]
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ethanol + acetyl-CoA = ethyl acetate + CoA
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acetyl-CoA + cortisol = CoA + cortisol 21-acetate
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acetyl-CoA + alpha-D-galactosamine 1-phosphate = CoA + N-acetyl-alpha-D-galactosamine 1-phosphate
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acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N6-acetyl-L-lysine
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acetyl-CoA + D-glucosamine = CoA + N-acetyl-D-glucosamine
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acetyl-CoA + malonyl-[acyl-carrier protein] = 3-oxobutanoyl-[acyl-carrier protein] + CoA + CO2
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acetyl-CoA + alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-decaprenol = CoA + 2-O-acetyl-alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-decaprenol
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acetyl-CoA + L-lysine = CoA + N6-acetyl-L-lysine
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acetyl-CoA + 6-diazo-5-oxo-L-norleucine = CoA + N-acetyl-6-diazo-5-oxo-L-norleucine
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acetyl-CoA + a [beta-tubulin]-L-lysine = CoA + a [beta-tubulin]-N6-acetyl-L-lysine
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acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine
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acetyl-CoA + L-histidine = CoA + N-acetyl-L-histidine
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acetyl-CoA + D-tryptophan = CoA + acetyl-D-tryptophan
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acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein]
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acetyl-CoA + an [acyl-carrier protein] = CoA + an acetyl-[acyl-carrier protein]
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acetyl-CoA + N-acetylneuraminate = CoA + N-acetyl-4-O-acetylneuraminate
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