Information on EC 2.7.3.2 - creatine kinase

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The expected taxonomic range for this enzyme is: Metazoa

EC NUMBER
COMMENTARY
2.7.3.2
-
RECOMMENDED NAME
GeneOntology No.
creatine kinase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
phospho group transfer
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Arginine and proline metabolism
-
creatine-phosphate biosynthesis
-
Metabolic pathways
-
SYSTEMATIC NAME
IUBMB Comments
ATP:creatine N-phosphotransferase
N-Ethylglycocyamine can also act as acceptor.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
adenosine triphosphate-creatine transphosphorylase
-
-
-
-
ATP: creatine N-phosphotransferase
-
-
ATP: creatine N-phosphotransferase
-
-
ATP:creatine phosphotransferase
-
-
-
-
BB-CK
-
-
-
-
BB-CK
-
brain-type cytosolic isoform of creatine kinase
BB-CK
P12277
-
BB-type creatine kinase
-
-
brain creatine kinase
-
-
brain creatine kinase
-
-
brain creatine kinase
-
-
brain type creatine kinase
-
-
brain-type creatine kinase
-
-
CK
-
-
-
-
CK-B
-
-
CK-BB
-
-
-
-
CK-BB
-
-
CK-MB
-
-
-
-
CK-MM
-
-
-
-
CKMiMi
-
-
-
-
creatine kinase
-
-
creatine kinase
-
-
creatine kinase
-
-
creatine kinase
Q7ZYQ9, Q8AVH2
-
creatine N-phosphotransferase
-
-
creatine phosphokinase
-
-
-
-
creatine phosphotransferase
-
-
-
-
creatinine kinase
-
-
hBBCK
-
-
kinase, creatine (phosphorylating)
-
-
-
-
MB-CK
-
-
-
-
Mi-CK
-
-
-
-
MiMi-CK
-
-
-
-
mit-CK
-
-
mitochondrial creatine kinase
-
-
mitochondrial creatine kinase
-
-
MM-CK
-
-
-
-
MM-CK
-
muscle form of creatine kinase
muscle creatine kinase
-
-
muscle creatine kinase
-
-
muscle-type creatine kinase
Q90X19
-
muscle-type creatine kinase
-
-
phosphocreatine kinase
-
-
-
-
plasma creatine kinase
-
-
recombinant human brain-type creatine kinase
-
-
rHBCK
-
-
sMiCK
-
-
uMiCK
P06732
-
zMMCK
Q90X19
-
MM-type creatine kinase
-
-
additional information
-
the enzyme is a member of the phosphagen (guanidino) kinase family
additional information
-
the enzyme is a member of the phosphagen kinase superfamily of enzymes
additional information
-
the enzyme is a member of the phosphagen (guanidino) kinase family
CAS REGISTRY NUMBER
COMMENTARY
9001-15-4
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
4 isozymes encoded by 4 different genes: 2 cytosolic isozymes, a muscle-type MM-CK and a brain-type BB-CK or a heterodimer MB-CK, and 2 mitochondrial isozymes, a ubiquitous MiU-CK and a sarcomeric MiS-CK
-
-
Manually annotated by BRENDA team
calf
-
-
Manually annotated by BRENDA team
two isoforms, interconversion by reversible oxidation of protein sulfhydryl groups
-
-
Manually annotated by BRENDA team
Antarctic icefish
-
-
Manually annotated by BRENDA team
polychaete worm
-
-
Manually annotated by BRENDA team
2 cytosolic and a mitochondrial isozymes
-
-
Manually annotated by BRENDA team
herring
-
-
Manually annotated by BRENDA team
isoforms CK1, CK2
-
-
Manually annotated by BRENDA team
pigeon
-
-
Manually annotated by BRENDA team
mirror carp, three isoforms
-
-
Manually annotated by BRENDA team
recombinant cytoplasmic isoforms M1, M2, and B
-
-
Manually annotated by BRENDA team
zebrafish
-
-
Manually annotated by BRENDA team
recombinant mitochondrial isoform
-
-
Manually annotated by BRENDA team
tropical fruit bat
-
-
Manually annotated by BRENDA team
Frog
-
-
-
Manually annotated by BRENDA team
atlantic cod
-
-
Manually annotated by BRENDA team
4 isozymes encoded by 4 different genes: 2 cytosolic isozymes, a muscle-type MM-CK and a brain-type BB-CK or a heterodimer MB-CK, and 2 mitochondrial isozymes, a ubiquitous MiU-CK and a sarcomeric MiS-CK
Uniprot
Manually annotated by BRENDA team
nurse shark
-
-
Manually annotated by BRENDA team
recombinant cytoplasmic and mitochondrial isoforms
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
2 typical mitochondrial enzyme types, the sarcomeric and the ubiquitous, encoded by 2 different genes
-
-
Manually annotated by BRENDA team
4 isozymes encoded by 4 different genes: 2 cytosolic isozymes, a muscle-type MM-CK and a brain-type BB-CK or a heterodimer MB-CK, and 2 mitochondrial isozymes, a ubiquitous MiU-CK and a sarcomeric MiS-CK
-
-
Manually annotated by BRENDA team
acute myocardial infarction patient
-
-
Manually annotated by BRENDA team
computational approach to study the contribution of side chain residues to the very low pKa value of active site cysteine
Uniprot
Manually annotated by BRENDA team
expression in Escherichia coli
-
-
Manually annotated by BRENDA team
patients with Alzheimer’s disease
-
-
Manually annotated by BRENDA team
three isoforms
-
-
Manually annotated by BRENDA team
green sunfish
-
-
Manually annotated by BRENDA team
recombinant cytoplasmic isoforms M1, M2, and B
-
-
Manually annotated by BRENDA team
recombinant cytoplasmic isoforms M, B and mitochondrial isoform
-
-
Manually annotated by BRENDA team
rainbow trout
-
-
Manually annotated by BRENDA team
4 isozymes encoded by 4 different genes: 2 cytosolic isozymes, a muscle-type MM-CK and a brain-type BB-CK or a heterodimer MB-CK, and 2 mitochondrial isozymes, a ubiquitous MiU-CK and a sarcomeric MiS-CK
-
-
Manually annotated by BRENDA team
commercial preparation
Uniprot
Manually annotated by BRENDA team
cytosolic isozyme
Uniprot
Manually annotated by BRENDA team
isozymes CK-MM, CK-BB, and CK-MB
-
-
Manually annotated by BRENDA team
red sea bream
-
-
Manually annotated by BRENDA team
monkey
-
-
Manually annotated by BRENDA team
21-day-old Wistar rats
-
-
Manually annotated by BRENDA team
treatment with single injection or for one week with daily injection of saline or L-Arg plus Nomega-nitro-L-arginine methyl ester or alpha-tocopherol plus ascorbic acid
-
-
Manually annotated by BRENDA team
Rattus norvegicus Wistar
Wistar
-
-
Manually annotated by BRENDA team
pacific mackerel
-
-
Manually annotated by BRENDA team
sea urchin, two isoforms
-
-
Manually annotated by BRENDA team
syn. Pseudemys scripta elegans, freshwater turtle
-
-
Manually annotated by BRENDA team
trout
-
-
-
Manually annotated by BRENDA team
creatine kinase activity and protein are 20% lower during hibernation than in euthermia, whereas enzyme mRNA is reduced by 70%. Hibernator creatine kinase shows reduced affinity for ATP and creatine. Soluble enzyme from euthermic squirrels is a mix of phosphorylated and dephosphorylated forms. in hibernating animals only phospho-enzyme is detected
-
-
Manually annotated by BRENDA team
TEMPERATURE RANGE
TEMPERATURE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
20
25
Q90X19
optimal temperature