Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cystine | inhibits creatine kinase activity possibly by oxidation of the sulfhydryl groups of the enzyme. Considering that creatine kinase like other thiol-containing enzymes, is crucial for energy homeostasis and antioxidant defenses, the enzymes inhibition caused by cystine released from lysosomes could be one of the mechanisms of tissue damage in patients with cystinosis | Rattus norvegicus | |
cystine dimethylester | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar | - |
Rattus norvegicus Wistar | - |
Wistar | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain cortex | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphocreatine | - |
Rattus norvegicus | ATP + creatine | - |
? | |
ADP + phosphocreatine | - |
Rattus norvegicus Wistar | ATP + creatine | - |
? |