EC Number   |
Application |
Reference |
|---|
   2.7.3.2 | biotechnology |
stability of immobilized enzyme |
642382 |
| 2.7.3.2 | biotechnology |
use as biomarker of sperm cell membrane degradation |
642426 |
| 2.7.3.2 | diagnostics |
enzyme is clinically important as an indicator of myocardial and skeletal muscle disorders and for the diagnosis of acute myocardial infarction |
661528 |
| 2.7.3.2 | medicine |
changes in the kinetics of the creatine kinase shuttle are sensitive markers of cardiac energetics |
762027 |
| 2.7.3.2 | medicine |
enzyme properties relevant for analysis |
642388 |
| 2.7.3.2 | medicine |
ethylmalonic acid accumulates in patients affected by short-chain acyl-CoA dehydrogenase deficiency and other diseases. Ethylmalonic acid inhibits the activity of respiratory chain complexes and also inhibits creatine kinase at concentrations o 1 mM and 5 mM and may therefore compromise energy metabolism in skeletal muscle |
675781 |
| 2.7.3.2 | medicine |
increased troponin I levels in the presence of rest pain and normal creatine kinase is not a spurious finding, but may actually be a marker of advanced coronary artery disease. However, some of these patients may also have nonsignificant coronary artery disease |
688203 |
| 2.7.3.2 | medicine |
levels of both free and protein-bound 4-hydroxy-2-nonenal are increased in alzheimers disease brain. 4-Hydroxy-2-nonenal inhibitis creatine kinase dose-dependently and forms adducts with specific amino acids including the active site residues H66, H191, C283, and H296 |
673067 |
| 2.7.3.2 | medicine |
mutations in the dysferlin gene cause several muscular dystrophy phenotypes including limb girdle 2B, Miyoshi myopathy, and distal anterior compartment myopathy. These disorders are characterized by autosomal recessive inheritance, early adult onset, and elevated levels of serum creatine kinase |
689192 |
| 2.7.3.2 | medicine |
neurotoxicitiy of L-arginine in hyperargininemia may in part be due to inhibition of creatine kinase |
675783 |
