Reference on EC 3.2.1.209 - endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ziegler, F.D.; Trimble, R.B.
Glycoprotein biosynthesis in yeast: purification and characterization of the endoplasmatic reticulum Man9 processing alpha-mannosidase
Glycobiology
1
605-614
1991
Saccharomyces cerevisiae
Jelinek-Kelly, S.; Herscovics, A.
Glycoprotein biosynthesis in Saccharomyces cerevisiae. Purification of the alpha-mannosidase which removes one specific mannose residue from Man9GlcNAc
J. Biol. Chem.
263
14757-14763
1988
Saccharomyces cerevisiae
Lipari, F.; Herscovics, A.
Production, purification and characterization of recombinant yeast processing alpha 1,2-mannosidase
Glycobiology
4
697-702
1994
Saccharomyces cerevisiae
Lipari, F.; Herscovics, A.
Calcium Binding to the Class I alpha-1,2-mannosidase from Saccharomyces cerevisiae occurs outside the EF hand motif
Biochemistry
38
1111-1118
1999
Saccharomyces cerevisiae
Romero, P.A.; Vallee, F.; Howell, P.L.; Herscovics, A.
Mutation of Arg273 to Leu alters the specificity of the yeast N-glycan processing class I alpha-1,2-mannosidase
J. Biol. Chem.
275
11071-11074
2000
Saccharomyces cerevisiae (P32906), Saccharomyces cerevisiae
Gonzalez, D.S.; Karaveg, K.; Vandersall-Nairn, A.S.; Lal, A.; Moremen, K.W.
Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis
J. Biol. Chem.
274
21375-21386
1999
Homo sapiens (Q9UKM7), Homo sapiens
Lipari, F.; Herscovics, A.
Role of the cysteine residues in the alpha-1,2-mannosidase involved in N-glycan biosynthesis in Saccharomyces cerevisiae. The conserved Cys340 and Cys385 residues form an essential disulfide bond
J. Biol. Chem.
271
27615-27622
1996
Saccharomyces cerevisiae
Lobsanov, Y.D.; Vallee, F.; Imberty, A.; Yoshida, T.; Yip, P.; Herscovics, A.; Howell, P.L.
Structure of Penicillium citrinum alpha-1,2-mannosidase reveals the basis for differences in specificity of the endoplasmic reticulum and golgi class I enzymes
J. Biol. Chem.
277
5620-5630
2002
Saccharomyces cerevisiae (P32906), Saccharomyces cerevisiae, Homo sapiens (Q9UKM7), Homo sapiens
Hamagashira, N.; Oku, H.; Mega, T.; Hase, S.
Purification and characterization of hen oviduct alpha 1,2-mannosidase
J. Biochem.
119
998-1003
1996
Gallus gallus
Yoshida, T.; Kato, Y.; Asada, Y.; Nakajima, T.
Filamentous fungus Aspergillus oryzae has two types of alpha-1,2-mannosidases, one of which is a microsomal enzyme that removes a single mannose residue from Man9GlcNAc2
Glycoconj. J.
17
745-748
2001
Aspergillus oryzae
Dole, K.; Lipari, F.; Herscovics, A.; Howell, P.L.
Crystallization and preliminary X-ray analysis of the class 1 alpha 1,2-mannosidase from Saccharomyces cerevisiae
J. Struct. Biol.
120
69-72
1997
Saccharomyces cerevisiae
Bieberich E.;Treml K.;Volker C.;Rolfs A.;Kalz-Fuller B.;Bause E
Man9-mannosidase from pig liver is a type-II membrane protein that resides in the endoplasmic reticulum. cDNA cloning and expression of the enzyme in COS 1 cells
Eur. J. Biochem.
246
681-689
1997
Sus scrofa
Karaveg, K.; Siriwardena, A.; Tempel, W.; Liu, Z.; Glushka, J.; Wang, B.; Moremen, K.W.
Mechanism of class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control
J. Biol. Chem.
280
16197-16207
2005
Homo sapiens (Q9UKM7)
Karaveg, K.; Moremen, K.W.
Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control
J. Biol. Chem.
280
29837-29848
2005
Homo sapiens (Q9UKM7)
Mora-Montes, H.M.; Lopez-Romero, E.; Zinker, S.; Ponce-Noyola, P.; Flores-Carreon, A.
Conversion of alpha1,2-mannosidase E-I from Candida albicans to alpha1,2-mannosidase E-II by limited proteolysis
Antonie van Leeuwenhoek
93
61-69
2008
Candida albicans
Hosokawa, N.; You, Z.; Tremblay, L.O.; Nagata, K.; Herscovics, A.
Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases
Biochem. Biophys. Res. Commun.
362
626-632
2007
Homo sapiens, Mus musculus (P39098), Mus musculus (P45700)
Mulakala, C.; Nerinckx, W.; Reilly, P.J.
The fate of beta-D-mannopyranose after its formation by endoplasmic reticulum alpha-(1-->2)-mannosidase I catalysis
Carbohydr. Res.
342
163-169
2007
Homo sapiens, Saccharomyces cerevisiae (P32906), Saccharomyces cerevisiae
Mora-Montes, H.M.; Lopez-Romero, E.; Zinker, S.; Ponce-Noyola, P.; Flores-Carreon, A.
Purification of soluble alpha1,2-mannosidase from Candida albicans CAI-4
FEMS Microbiol. Lett.
256
50-56
2006
Candida albicans
Wu, Y.; Termine, D.J.; Swulius, M.T.; Moremen, K.W.; Sifers, R.N.
Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis
J. Biol. Chem.
282
4841-4849
2007
Homo sapiens, Mus musculus
Mast, S.W.; Moremen, K.W.
Family 47 alpha-mannosidases in N-glycan processing
Methods Enzymol.
415
31-46
2006
Saccharomyces cerevisiae (P32906), Homo sapiens (Q9UKM7)
Avezov, E.; Frenkel, Z.; Ehrlich, M.; Herscovics, A.; Lederkremer, G.Z.
Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation
Mol. Biol. Cell
19
216-225
2008
Mus musculus
Cantu, D.; Nerinckx, W.; Reilly, P.J.
Theory and computation show that Asp463 is the catalytic proton donor in human endoplasmic reticulum alpha-(1-->2)-mannosidase I
Carbohydr. Res.
343
2235-2242
2008
Homo sapiens (Q9UKM7), Homo sapiens
Mora-Montes, H.M.; Lopez-Romero, E.; Zinker, S.; Ponce-Noyola, P.; Flores-Carreon, A.
Heterologous expression and biochemical characterization of an alpha1,2-mannosidase encoded by the Candida albicans MNS1 gene
Mem. Inst. Oswaldo Cruz
103
724-730
2008
Candida albicans (Q8J0Q0), Candida albicans
Mora-Montes, H.M.; Bader, O.; Lopez-Romero, E.; Zinker, S.; Ponce-Noyola, P.; Hube, B.; Gow, N.A.; Flores-Carreon, A.
Kex2 protease converts the endoplasmic reticulum alpha1,2-mannosidase of Candida albicans into a soluble cytosolic form
Microbiology
154
3782-3794
2008
Candida albicans (Q8J0Q0), Candida albicans, Candida albicans ATCC 26555 (Q8J0Q0)
Hosokawa, N.; Tremblay, L.O.; Sleno, B.; Kamiya, Y.; Wada, I.; Nagata, K.; Kato, K.; Herscovics, A.
EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans
Glycobiology
20
567-575
2010
Homo sapiens
Pan, S.; Huang, L.; McPherson, J.; Muzny, D.; Rouhani, F.; Brantly, M.; Gibbs, R.; Sifers, R.N.
Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency
Hepatology
50
275-281
2009
Homo sapiens
Rafiq, M.; Kuss, A.; Puettmann, L.; Noor, A.; Ramiah, A.; Ali, G.; Hu, H.; Kerio, N.; Xiang, Y.; Garshasbi, M.; et al
Mutations in the alpha 1,2-mannosidase gene, MAN1B1, cause autosomal-recessive intellectual disability
Am. J. Hum. Genet.
89
176-182
2011
Homo sapiens
Groisman, B.; Shenkman, M.; Ron, E.; Lederkremer, G.Z.
Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps
J. Biol. Chem.
286
1292-1300
2011
Homo sapiens
Mora-Montes, H.M.; Robledo-Ortiz, C.I.; Gonzalez-Sanchez, L.C.; Lopez-Esparza, A.; Lopez-Romero, E.; Flores-Carreon, A.
Purification and biochemical characterisation of endoplasmic reticulum alpha1,2-mannosidase from Sporothrix schenckii
Mem. Inst. Oswaldo Cruz
105
79-85
2010
Sporothrix schenckii, Sporothrix schenckii EH206
Liebminger, E.; Huettner, S.; Vavra, U.; Fischl, R.; Schoberer, J.; Grass, J.; Blaukopf, C.; Seifert, G.J.; Altmann, F.; Mach, L.; Strasser, R.
Class I alpha-mannosidases are required for N-glycan processing and root development in Arabidopsis thaliana
Plant Cell
21
3850-3867
2009
Arabidopsis thaliana (Q93Y37)
Vallee, F.; Lipari, F.; Yip, P.; Sleno, B.; Herscovics, A.; Howell, P.L.
Crystal structure of a class I alpha1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control
EMBO J.
19
581-588
2000
Saccharomyces cerevisiae (P32906), Saccharomyces cerevisiae, Saccharomyces cerevisiae ATCC 204508 (P32906)
Lal, A.; Pang, P.; Kalelkar, S.; Romero, P.A.; Herscovics, A.; Moremen, K.W.
Substrate specificities of recombinant murine Golgi alpha-1,2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing alpha-1,2-mannosidases
Glycobiology
8
981-995
1998
Rattus norvegicus
Pan, Y.T.; Kaushal, G.P.; Papandreou, G.; Ganem, B.; Elbein, A.D.
D-Mannonolactam amidrazone. A new mannosidase inhibitor that also inhibits the endoplasmic reticulum or cytoplasmic alpha-mannosidase
J. Biol. Chem.
267
8313-8318
1992
Rattus norvegicus
Hosokawa, N.; Kamiya, Y.; Kamiya, D.; Kato, K.; Nagata, K.
Human OS-9, a lectin required for glycoprotein ERAD, recognizes mannose-trimmed N-glycans
J. Biol. Chem.
284
17061-17068
2009
Mus musculus (Q2HXL6), Homo sapiens (Q9UKM7), Homo sapiens
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