Literature summary for 3.2.1.209 extracted from

Romero, P.A.; Vallee, F.; Howell, P.L.; Herscovics, A.
Mutation of Arg273 to Leu alters the specificity of the yeast N-glycan processing class I alpha-1,2-mannosidase (2000), J. Biol. Chem., 275, 11071-11074.

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Protein Variants

Protein Variants	Comment	Organism
R273L	instead of Man8GlcNAc, substrate is transformed to Man5GlcNAc	Saccharomyces cerevisiae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	-	Saccharomyces cerevisiae	5783	-

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	P32906	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Manalpha(1-2)Manalpha(1-6)(Manalpha(1-2)Manalpha(1-3))Manalpha(1-6)Manalpha(1-2)Manalpha(1-2)Manalpha(1-3)Manbeta(1-4)GlcNAc + 4 H2O	mutant R273L	Saccharomyces cerevisiae	(Man)5GlcNAc + 4 D-mannose	product of mutant R273L, product of wild type is Man8GlcNAc	?

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Release 2023.1 (January 2023)