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Also reduces 1-pyrroline-3-hydroxy-5-carboxylate to L-hydroxyproline.
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The enzyme appears in viruses and cellular organisms
1-pyrroline-5-carboxylate reductase, DELTA1-pyrroline-5-carboxylate reductase, L-proline oxidase, L-proline-NAD(P)+ 5-oxidoreductase, L-proline:NAD(P)+ 5-oxidoreductase, MTR_7g090160
, NADPH-L-DELTA'-pyrroline carboxylic acid reductase, P5C reductase, P5CDH, P5CR, more
L-proline + NAD(P)+ = 1-pyrroline-5-carboxylate + NAD(P)H + H+