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Literature summary for 1.5.1.2 extracted from

  • Herzfeld, A.; Mezl, V.A.; Knox, W.E.
    Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues (1977), Biochem. J., 166, 95-103.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.5.1.2

Inhibitors

Inhibitors Comment Organism Structure
NAD+
-
 Rattus norvegicus
proline
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.58
-
 NADH
-
 Rattus norvegicus
0.62
-
 DL-pyrroline-5-carboxylate
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information distribution in fetal and tumor tissues Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-pyrroline-5-carboxylate + NAD(P)H + H+ specific for L-isomer Rattus norvegicus L-proline + NAD(P)+
-
 ir
L-Pro + NAD+
-
 Rattus norvegicus 1-pyrroline-5-carboxylate + NADH
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
-
-
 complete inactivation after 30 min Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADH preferentially Rattus norvegicus
NADPH
-
 Rattus norvegicus