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BRENDA support

Ligand NADPH

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Basic Ligand Information

Molecular Structure
Picture of NADPH (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C21H30N7O17P3
NADPH
ACFIXJIJDZMPPO-NNYOXOHSSA-N
Synonyms:
2'-NADPH, beta-NADPH, NAD(P)H, NAPDH, Nicotinamide adenine dinucleotide-diphosphate

Related pathways

Pathway Source
Pathways
BRENDA
3-chlorocatechol degradation, 3-phenylpropionate degradation, 4-hydroxymandelate degradation, acetate fermentation, acetyl CoA biosynthesis more
MetaCyc
(+)-pisatin biosynthesis, (-)-glycinol biosynthesis, (-)-maackiain biosynthesis, (-)-medicarpin biosynthesis, (1'S,5'S)-averufin biosynthesis more


Show all pahtways known for Show all BRENDA pathways known for NADPH

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3805 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-(4-hydroxyphenyl)pyruvate + NAD(P)H = (R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
show the reaction diagram
-
fructose + NADPH = sorbitol + NADP+
show the reaction diagram
-
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH = 2-dehydro-3-deoxy-D-gluconate + NADP+
show the reaction diagram
-
2,5-didehydro-3-deoxy-D-gluconate + NADPH + H+ = 2-dehydro-3-deoxy-D-gluconate + NADP+
show the reaction diagram
-
(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H = 3-dehydro-L-gulonate + NAD(P)+
show the reaction diagram
-
D-mannuronate + NADPH = D-mannonate + NADP+
show the reaction diagram
-
TDP-6-deoxy-D-xylo-4-hexosulose + NADPH = TDP-6-deoxy-L-talose + NADP+
show the reaction diagram
-
GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H = GDP-6-deoxy-D-talose + NAD(P)+
show the reaction diagram
-
D-fructose + NADPH = D-mannitol + NADP+
show the reaction diagram
-
3-acetoacetyl-CoA + NADPH + H+ = (S)-3-hydroxybutanoyl-CoA + NADP+
show the reaction diagram
-
(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH = ?
show the reaction diagram
-
diacetyl + NAD(P)H = acetoin + NADP+
show the reaction diagram
-
D-fructose 6-phosphate + NADPH + H+ = D-mannitol 1-phosphate + NADP+
show the reaction diagram
-
12-oxolithocholic acid + NADPH + H+ = deoxycholic acid + NADP+
show the reaction diagram
-
indole-3-acetaldehyde + NADPH = indole-3-ethanol + NADP+
show the reaction diagram
-
D-glucose 6-phosphate + NADPH + H+ = D-sorbitol 6-phosphate + NADP+
show the reaction diagram
-
2 benzyl 2-methyl-3-oxobutyrate + 2 NADPH + 2 H+ = benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + benzyl (2S,3S)-2-methyl-3-hydroxybutanoate + 2 NADP+
show the reaction diagram
-
6-pyruvoyltetrahydropterin + NADPH = 6-lactoyl-5,6,7,8-tetrahydropterin + NADP+
show the reaction diagram
-
diethyl 2-methyl-3-oxosuccinate + NADPH = diethyl 2-methyl-3-hydroxysuccinate + NADP+
show the reaction diagram
-
daunorubicin + NADPH + H+ = daunorubicinol + NADP+
show the reaction diagram
-
1,5-anhydro-D-fructose + NADPH = 1,5-anhydro-D-glucitol + NADP+
show the reaction diagram
vellosimine + NADPH = 10-deoxysarpagine + NADP+
show the reaction diagram
-
5alpha-pregnan-3,20-dione + NADPH = 3beta-hydroxy-5alpha-pregnane-20-one + NADP+
show the reaction diagram
-
3''-deamino-3''-oxonicotianamine + NAD(P)H + H+ = 2'-deoxymugineic acid + NAD(P)+
show the reaction diagram
-
1,5-anhydro-D-fructose + NADPH + H+ = 1,5-anhydro-D-mannitol + NADP+
show the reaction diagram
2-sulfoacetaldehyde + NADPH + H+ = isethionate + NADP+
show the reaction diagram
perakine + NADPH + H+ = raucaffrinoline + NADP+
show the reaction diagram
-
benzil + NADPH + H+ = (S)-benzoin + NADP+
show the reaction diagram
-
a very-long-chain 3-oxoacyl-CoA + NADPH + H+ = a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+
show the reaction diagram
-
methyl ecgonone + NADPH + H+ = methyl ecgonine + NADP+
show the reaction diagram
-
(3R)-vestitone + NADPH + H+ = (3R,4R)-4'-methoxyisoflavan-2',4,7-triol + NADP+
show the reaction diagram
-
norsolorinic acid + NADPH + H+ = (1'S)-averantin + NADP+
show the reaction diagram
-
3-oxofumonisin B3 + NADPH = fumonisin B3 + NADP+
show the reaction diagram
-
2'-dehydrokanamycin A + NADPH + H+ = kanamycin A + NADP+
show the reaction diagram
-
GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NAD(P)H + H+ = GDP-beta-L-colitose + NAD(P)+
show the reaction diagram
-
2-dehydropantolactone + NADPH + H+ = (R)-pantolactone + NADP+
show the reaction diagram
-
aklaviketone + NADPH + H+ = aklavinone + NADP+
show the reaction diagram
-
D-galacturonate + NADPH + H+ = L-galactonate + NADP+
show the reaction diagram
-
3-sulfopyruvate + NADPH + H+ = (2S)-3-sulfolactate + NADP+
show the reaction diagram
-
(R)-2-alkyl-3-oxoalkanoate + NADPH + H+ = (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+
show the reaction diagram
-
6-dehydro-Virginiae butanolide-A + NADPH + H+ = (2R,3R,6S)-Virginiae butanolide-A + NADP+
show the reaction diagram
-
UDP-2-acetamido-2,6-dideoxy-alpha-D-xylohex-4-ulose + NAD(P)H + H+ = UDP-N-acetyl-alpha-D-quinovosamine + NAD(P)+
show the reaction diagram
-
2-sulfoacetaldehyde + NADPH + H+ = isethionate + NADP+
show the reaction diagram
-
rhazimal + NADPH + H+ = rhazimol + NADP+
show the reaction diagram
-
dolichal + NADPH + H+ = dolichol + NADP+
show the reaction diagram
-
questin + NADPH + H+ + O2 = demethylsulochrin + NADP+
show the reaction diagram
-
L-lactaldehyde + NADPH + H+ = propane-1,2-diol + NADP+
show the reaction diagram
-
tartronate semialdehyde + NAD(P)H = (R)-glycerate + NAD(P)+
show the reaction diagram
-
D-glyceraldehyde + NADPH + H+ = glycerol + NADP+
show the reaction diagram
-
methylglyoxal + NADPH = lactaldehyde + NADP+
show the reaction diagram
-
benzaldehyde + NAD(P)H + H+ = benzyl alcohol + NAD(P)+
show the reaction diagram
-
2-hydroxy-3-oxosuccinate + NAD(P)H = D-glycerate + NAD(P)+ + CO2
show the reaction diagram
-
(2S)-2-(methylamino)-1-phenylpropan-1-one + NADPH + H+ = (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + NADP+
show the reaction diagram
-
norsolorinate + NADPH + H+ = (1'S)-averantin + NADP+
show the reaction diagram
-
3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+ = mevalonate + CoA + 2 NADP+
show the reaction diagram
-
3-quinuclidinone + NADPH + H+ = (R)-3-quinuclidinol + NADP+
show the reaction diagram
-
3-quinuclidinone + NADPH + H+ = (S)-3-quinuclidinol + NADP+
show the reaction diagram
-
hyoscyamine aldehyde + NADPH + H+ = hyoscyamine + NAD+
show the reaction diagram
-
H+ + NADPH = H2 + NADP+
show the reaction diagram
-
H2 + NADPH = NADP + H+
show the reaction diagram
-
9H-carbazole + NADPH + H+ + O2 = 2'-aminobiphenyl-2,3-diol + NADP+
show the reaction diagram
-
salicylate + O2 + NADPH + 2 H+ = catechol + CO2 + H2O + NADP+
show the reaction diagram
-
urate + NADPH + H+ + O2 = 5-hydroxyisourate + NADP+ + H2O
show the reaction diagram
-
trans-cinnamate + NADPH + O2 = 2-hydroxycinnamate + NADP+ + H2O
show the reaction diagram
-
N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O
show the reaction diagram
-
(+)-sabinene + NADPH + H+ + O2 = (+)-cis-sabinol + NADP+ + H2O
show the reaction diagram
-
erythromycin D + NADPH + H+ + O2 = erythromycin C + NADP+ + H2O
show the reaction diagram
-
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + O2 + NADPH + H+ = [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+ + H2O
show the reaction diagram
-
4-nitrocatechol + NAD(P)H + H+ + O2 = 2-hydroxy-1,4-benzoquinone + nitrite + NAD(P)+ + H2O
show the reaction diagram
-
(indol-3-yl)pyruvate + NADPH + H+ + O2 = (indol-3-yl)acetate + NADP+ + H2O + CO2
show the reaction diagram
-
salicylate + NADPH + H+ + O2 = 2,5-dihydroxybenzoate + NADP+ + H2O
show the reaction diagram
-
aklavinone + NADPH + H+ + O2 = epsilon-rhodomycinone + NADP+ + H2O
show the reaction diagram
-
dTDP-beta-L-evernosamine + 2 NADPH + 2 H+ + 2 O2 = dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 NADP+ + 3 H2O
show the reaction diagram
-
5-methyl-1-naphthoate + NADPH + H+ + O2 = 3-hydroxy-5-methyl-1-naphthoate + NADP+ + H2O
show the reaction diagram
-
4-methyl-5-nitrocatechol + O2 + NADPH + H+ = 2-hydroxy-5-methylquinone + nitrite + H2O + NADP+
show the reaction diagram
-
rifampicin + NAD(P)H + O2 = 2-hydroxy-2,27-secorifampicin + NAD(P)+ + H2O
show the reaction diagram
-
resorcinol + NADPH + H+ + O2 = hydroxyquinol + NADP+ + H2O
show the reaction diagram
-
[F-actin]-L-methionine + NADPH + O2 + H+ = [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O
show the reaction diagram
-
acetone + NADPH + H+ + O2 = methyl acetate + NADP+ + H2O
show the reaction diagram
-
4-hydroxy-6-methylpretetramide + NADPH + H+ + O2 = 4-de(dimethylamino)-4-oxoanhydrotetracycline + NADP+ + H2O
show the reaction diagram
-
dimethylamine + NADPH + H+ + O2 = methylamine + formaldehyde + NADP+ + H2O
show the reaction diagram
-
L-carnitine + NADPH + H+ + O2 = (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O
show the reaction diagram
-
3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + O2 + H3O+ = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+ + H2O
show the reaction diagram
-
3-amino-4-hydroxybenzoate + NADPH + H+ + O2 = 3-amino-2,4-dihydroxybenzoate + NADP+ + H2O
show the reaction diagram
-
glycine betaine + NADPH + H+ + O2 = N,N-dimethylglycine + formaldehyde + NADP+ + H2O
show the reaction diagram
-
putrescine + NADPH + H+ + O2 = N-hydroxyputrescine + NADP+ + H2O
show the reaction diagram
-
4-hydroxybenzoate + NADPH + H+ + O2 = 3,4-dihydroxybenzoate + NADP+ + H2O
show the reaction diagram
-
(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate + NADPH + O2 = 20-hydroxy-leukotriene E4 + NADP+ + H2O
show the reaction diagram
-
anthranilate + NADPH + O2 = 2,3-dihydroxybenzoate + NADP+ + NH3
show the reaction diagram
-
(-)-menthol + NADPH + O2 = p-menthane-3,8-diol + NADP+ + H2O
show the reaction diagram
-
6-oxocineole + NADPH + O2 = 1,6,6-trimethyl-2,7-dioxabicyclo-[3.2.2]nonan-3-one + NADP+ + H2O
show the reaction diagram
-
progesterone + NADPH + H+ + O2 = Testosterone acetate + NADP+ + H2O
show the reaction diagram
-
Benzoyl-CoA + NADPH + O2 = ?
show the reaction diagram
-
2-Hydroxycyclohexan-1-one + NADPH + O2 = ?
show the reaction diagram
-
arachidonic acid + O2 + NADPH = 20-hydroxyeicosatetraenoic acid + H2O + NADP+
show the reaction diagram
-
tabersonine + NADPH + H+ + O2 = 16-hydroxytabersonine + NADP+ + H2O
show the reaction diagram
-
(1'S)-averantin + NADPH + H+ + O2 = (1'S,5'R)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
-
7alpha-hydroxycholest-4-en-3-one + NADPH + H+ + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + NADP+ + H2O
show the reaction diagram
-
lanosterol + O2 + NADPH + H+ = 4,4-dimethyl-5alpha-cholesta-8,14,24-triene-3beta-ol + formate + NADP+ + H2O
show the reaction diagram
-
heme + 2 NADPH + 2 H+ + 2 O2 = biliverdin + Fe2+ + CO + 2 NADP+ + H2O
show the reaction diagram
-
taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O
show the reaction diagram
-
progesterone + NADPH + O2 = 11alpha-hydroxyprogesterone + NADP+ + H2O
show the reaction diagram
-
phenol + NADPH + O2 = ?
show the reaction diagram
-
cholesterol + NADPH + O2 = (24S)-hydroxycholesterol + NADP+ + H2O
show the reaction diagram
-
(+)-limonene + NADPH + H+ + O2 = (+)-trans-carveol + NADP+ + H2O
show the reaction diagram
-
quinine + NADPH + O2 = 3-hydroxyquinine + NADP+ + H2O
show the reaction diagram
-
ent-sandaracopimaradiene + NADPH + H+ + O2 = ent-sandaracopimaradien-3beta-ol + NADP+ + H2O
show the reaction diagram
-
docosahexaenoate + NADPH + H+ + O2 = 22-hydroxydocosahexaenoate + NADP+ + H2O
show the reaction diagram
-
ent-kaur-16-ene + 3 NADPH + [reduced NADPH-hemoprotein reductase] + O2 = ent-kaur-16-en-19-oate + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
24-methylidenecycloartanol + NADPH + O2 + H+ = cycloeucalenol + NADP+ + H2O
show the reaction diagram
-
linoleate + NAD(P)H + O2 = crepenynate + NAD(P)+ + H2O
show the reaction diagram
-
alkyl ether plasmanylethanolamine + NADPH + O2 = vinyl ether phosphatidylethanolamine + NADP+ + H2O
show the reaction diagram
-
pentalenolactone F + O2 + NADPH + H+ = pentalenolactone + NADP+ + H2O
show the reaction diagram
-
estradiol-17beta + NADPH + O2 = 6beta-hydroxyestradiol-17beta + NADP+ + H2O
show the reaction diagram
-
kynurenate + NADPH + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + NADP+
show the reaction diagram
-
7-O-methylluteone + NADPH + O2 = dihydrofurano derivative of 7-O-methylluteone + NADP+ + H2O
show the reaction diagram
-
progesterone + NADPH + H+ + O2 = Testosterone acetate + NADP+ + H2O
show the reaction diagram
-
2 Fe(III)-siderophore + NADPH = 2 Fe(II)-siderophore + NADP+ + H+
show the reaction diagram
-
NADPH + cyanocob(III)alamin = NADP+ + cob(I)alamin + cyanide
show the reaction diagram
-
2 Fe(III)-siderophore + NADPH = 2 Fe(II)-siderophore + NADP+ + H+
show the reaction diagram
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CDP-4-dehydro-6-deoxy-D-glucose + NAD(P)H = CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD(P)+ + H2O
show the reaction diagram
-
CO2 + NADPH = formate + NADP+
show the reaction diagram
-
NADPH + O2 = NADP+ + O2- + H+
show the reaction diagram
-
oxidized ferredoxin + NADPH = reduced ferredoxin + NADP+
show the reaction diagram
L-tyrosine + NADPH + H+ + ATP = L-tyrosinal + NADP+ + AMP + diphosphate
show the reaction diagram
-
[amino-group carrier protein LysW]-C-terminal-gamma-(alpha-aminoadipate) phosphate + NADPH + H+ = [amino-group carrier protein LysW]-C-terminal-gamma-aminoadipic semialdehyde + phosphate + NADP+
show the reaction diagram
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malonyl-CoA + NADPH = malonate-semialdehyde + CoA + NADP+
show the reaction diagram
-
N-acetyl-L-glutamyl 5-phosphate + NADPH + H+ = N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate
show the reaction diagram
-
L-5-glutamyl phosphate + NADPH = ?
show the reaction diagram
-
tetradecanoyl-CoA + NADPH + H+ = tetradecanal + CoA + NADP+
show the reaction diagram
-
3-phospho-D-glyceroyl phosphate + NADPH + H+ = D-glyceraldehyde 3-phosphate + phosphate + NADP+
show the reaction diagram
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L-glutamyl-tRNAGlu + NADPH + H+ = L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
show the reaction diagram
-
sulfoacetyl-CoA + NADPH + H+ = 2-sulfoacetaldehyde + CoA + NADP+
show the reaction diagram
-
3-phospho-D-glyceroyl phosphate + NADPH + H+ = D-glyceraldehyde 3-phosphate + phosphate + NADP+
show the reaction diagram
-
L-2-aminoadipate + NADPH + H+ + ATP = (S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate
show the reaction diagram
-
stearoyl-CoA + NADPH = octadecanal + CoA + NADP+
show the reaction diagram
-
2,4-dichlorobenzoyl-CoA + NADPH = 4-chlorobenzoyl-CoA + NADP+ + chloride
show the reaction diagram
-
chanoclavine-I aldehyde + NADPH + H+ = dihydrochanoclavine-I aldehyde + NADP+
show the reaction diagram
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acrolein + NADPH + H+ = ? + NADP+
show the reaction diagram
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crotonyl-[acyl-carrier-protein] + NADPH + H+ = butyryl-[acyl-carrier-protein] + NADP+
show the reaction diagram
-
geranylgeranyl-bacteriochlorophyll a + 3 NADPH + 3 H+ = phytyl-bacteriochlorophyll a + 3 NADP+
show the reaction diagram
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cyclohex-1-ene-1-carbonyl-CoA + NADPH + H+ = cyclohexane-1-carbonyl-CoA + NADP+
show the reaction diagram
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(6E)-8-oxogeranial + NADPH + H+ = (S)-8-oxocitronellyl enol + NADP+
show the reaction diagram
-
precondylocarpine acetate + NADPH + H+ = dihydroprecondylocarpine acetate + NADP+
show the reaction diagram
-
orotate + NADPH = (S)-dihydroorotate + NADP+
show the reaction diagram
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3-nitroacrylate + NADPH = 3-nitropropanoate + NADP+
show the reaction diagram
-
(+)-costunolide + NADPH = 11(S),13-dihydrocostunolide + NADP+
show the reaction diagram
-
trans-trans-2,4-hexadecadienoyl-CoA + NADPH = trans-2-hexadecenoyl-CoA + NADP+
show the reaction diagram
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trans-didehydroacyl-CoA + NAD(P)H = acyl-CoA + NAD(P)+
show the reaction diagram
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6,7-dihydroxy-4'-methoxyisoflavone + NADPH + H+ = (3S)-2-dihydrobiochanin A + NADP+
show the reaction diagram
-
alpha-santonin + NAD(P)H = 1,2-dihydrosantonin + NAD(P)+
show the reaction diagram
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trans-zeatin + NADPH = dihydrozeatin + NADP+
show the reaction diagram
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(-)-isopiperitenone + NADPH + H+ = (+)-cis-isopulegone + NADP+
show the reaction diagram
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acrylyl-CoA + NADPH + H+ = propanoyl-CoA + NADP+
show the reaction diagram
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uracil47 in tRNA + NAD(P)H + H+ = 5,6-dihydrouracil20 in tRNA + NAD(P)+
show the reaction diagram
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artemisinic aldehyde + NADPH + H+ = (11R)-dihydroartemisinic aldehyde + NADP+
show the reaction diagram
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presqualene diphosphate + NADPH + H+ = squalene + diphosphate + NADP+
show the reaction diagram
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(2E,4E,6E,10Z)-4-methyl-11-[2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol-4-yl]undeca-2,4,6,10-tetraenoyl-[acyl-carrier-protein] + NADPH + H+ = (2E,4E,6E,10Z)-4-methyl-11-[2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol-4-yl]undeca-4,6,10-trienoyl-[acyl-carrier-protein] + NADP+
show the reaction diagram
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pyruvate + methylamine + NADPH = N-methyl-L-alanine + H2O + NADP+
show the reaction diagram
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oxaloacetate + NAD(P)H + NH4+ = L-aspartate + NAD(P)+
show the reaction diagram
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L-aspartic 4-semialdehyde + 1,3-diaminopropane + NADPH + H+ = carboxynorspermidine + NADP+ + H2O
show the reaction diagram
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L-glutamine + 2-oxoglutarate + reduced ferredoxin + NADPH + H+ = L-glutamate + oxidized ferredoxin + NADP+
show the reaction diagram
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berberine + NADPH = canadine + NADP+
show the reaction diagram
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FMN + NADPH + H+ = FMNH2 + NADP+
show the reaction diagram
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FMN + NADPH + H+ = FMNH2 + NADP+
show the reaction diagram
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coenzyme F420 + NADPH + H+ = reduced coenzyme F420 + NADP+
show the reaction diagram
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FMN + NADPH + H+ = FMNH2 + NADP+
show the reaction diagram
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DELTA1-pyrroline-2-carboxylate + NADPH + H+ = L-proline + NADP+
show the reaction diagram
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(2S)-2-amino-4-[[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoate + pyruvate + NADPH + H+ = staphylopine + NADP+ + H2O
show the reaction diagram
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5,10-methylenetetrahydrofolate + NADPH + H+ = 5-methyltetrahydrofolate + NADP+
show the reaction diagram
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agmatine + L-aspartate 4-semialdehyde + NADPH + H+ = N1-[(S)-3-amino-3-carboxypropyl]agmatine + NADP+ + H2O
show the reaction diagram
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18-hydroxynorfluorocurarine + NADPH + H+ = 17,18-epoxy-17-hydroxycur-19-ene + NADP+
show the reaction diagram
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(2S)-2-amino-4-([(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino)butanoate + pyruvate + NADPH + H+ = yersinopine + NADP+ + H2O
show the reaction diagram
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NADPH + NAD+ = NADP+ + NADH
show the reaction diagram
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NADPH + NAD+ = NADP+ + NADH
show the reaction diagram
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2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
demethylphylloquinone + NADPH + H+ = demethylphylloquinol + NADP+
show the reaction diagram
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NADPH + H+ + 2 monodehydroascorbate = NADP+ + 2 ascorbate
show the reaction diagram
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NAD(P)H + nitrate = ?
show the reaction diagram
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NAD(P)H + nitrite + H+ = NAD(P)+ + NH3 + H2O
show the reaction diagram
-
bis-gamma-glutamylcystine + NADPH + H+ = 2 gamma-glutamylcysteine + NADP+
show the reaction diagram
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CoA-disulfide + NAD(P)H + H+ = CoA + NAD(P)+
show the reaction diagram
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glutathione amide disulfide + NADPH + H+ = 2 glutathione amide + NADP+
show the reaction diagram
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sulfur + NAD(P)H + H+ = hydrogen sulfide + NAD(P)+
show the reaction diagram
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(sulfide)n+1 + NADPH + H+ = hydrogen sulfide + (sulfide)n + NADP+
show the reaction diagram
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protein disulfide + NAD(P)H = protein dithiol + NAD(P)+
show the reaction diagram
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[protein disulfide oxidoreductase]-disulfide + NADPH + H+ = [protein disulfide oxidoreductase]-dithiol + NADP+
show the reaction diagram
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5,10-methylenetetrahydrofolate + dUMP + NADPH = dTMP + tetrahydrofolate + NADP
show the reaction diagram
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5,10-methylenetetrahydrofolate + uracil54 in tRNA + NADPH + H+ = tetrahydrofolate + 5-methyluracil54 in tRNA + NADP+
show the reaction diagram
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eicosanoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ = tetramethyl-branched mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O
show the reaction diagram
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malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = CoA + isoliquiritigenin + CO2 + NADP+ + H2O
show the reaction diagram
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acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+ = 5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+
show the reaction diagram
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acetyl-CoA + 5 malonyl-CoA + 2 NADPH + 2 H+ = 2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+
show the reaction diagram
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malonyl-CoA + 5 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+ = 10-deoxymethynolide + 6 CoA + 6 CO2 + 5 NADP+ + 2 H2O
show the reaction diagram
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malonyl-CoA + 6 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+ = narbonolide + 7 CoA + 7 CO2 + 5 NADP+ + 2 H2O
show the reaction diagram
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acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O
show the reaction diagram
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a long-chain acyl-CoA + 3 (R)-methylmalonyl-CoA + 6 NADPH + 6 H+ + holo-[mycolipanoate synthase] = mycolipanoyl-[mycolipanoate synthase] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O
show the reaction diagram
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acetyl-CoA + malonyl-CoA + NADH + NADPH = ?
show the reaction diagram
8 malonyl-CoA + NADPH + H+ = 8 CoA + (4E,6E,8E,10E,12E,14E)-3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoic acid + NADP+ + H2O + CO2
show the reaction diagram
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(8S)-8-amino-7-oxononanoate + [protein]-L-lysine + NAD(P)H + H+ = [protein]-N6-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysine + H2O + NAD(P)+
show the reaction diagram
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NADPH + H2O = NADH + phosphate
show the reaction diagram
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NADPH + H2O = ?
show the reaction diagram
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L-tyrosine + S-adenosyl-L-methionine + NADPH = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP+ + H+
show the reaction diagram
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ATP + 3-hydroxypropionate + CoA + NADPH = AMP + diphosphate + NADP+ + propionyl-CoA
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1198 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-3-(imidazol-5-yl)lactate + NAD(P)+ = 3-(imidazol-5-yl)pyruvate + NAD(P)H
show the reaction diagram
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D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH + H+
show the reaction diagram
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L-fucose + NADP+ = L-fuconolactone + NADPH + H+
show the reaction diagram
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L-sorbose + NADP+ = 5-dehydro-D-fructose + NADPH + H+
show the reaction diagram
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D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH
show the reaction diagram
-
D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+
show the reaction diagram
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D-sorbitol 6-phosphate + NADP+ = D-fructose 6-phosphate + NADPH + H+
show the reaction diagram
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5D-5-O-methyl-chiro-inositol + NADP+ = 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H+
show the reaction diagram
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pregnenolone + NAD(P)+ = pregn-5-en-3,20-dione + NAD(P)H + H+
show the reaction diagram
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(S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H
show the reaction diagram
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glycerol + NADP+ = dihydroxyacetone + NADPH + H+
show the reaction diagram
-
taurochenodeoxycholic acid + NADP+ = tauro-7-ketolithocholic acid + NADPH + H+
show the reaction diagram
-
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D-mannitol 1-phosphate + NADP+ = D-fructose 6-phosphate + NADPH + H+
show the reaction diagram
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a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(P)+ = a 3-oxosteroid + CO2 + NAD(P)H
show the reaction diagram
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cholate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
show the reaction diagram
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sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
show the reaction diagram
286119, -
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TDP-D-glucose + 2 NADP+ + H2O = TDP-D-galacturonate + 2 NADPH + 2 H+
show the reaction diagram
-
prostaglandin D2 + NADP+ = 15-ketoprostaglandin D2 + NADPH + H+
show the reaction diagram
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prostaglandin E2 + NADP+ = 15-oxoprostaglandin E2 + NADPH + H+
show the reaction diagram
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L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH
show the reaction diagram
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D-sorbitol 6-phosphate + NADP+ = D-glucose 6-phosphate + NADPH + H+
show the reaction diagram
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farnesol + NADP+ = farnesal + NADPH
show the reaction diagram
-
D-mannitol 1-phosphate + NADP+ = D-mannose 6-phosphate + NADPH + H+
show the reaction diagram
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3alpha-hydroxyglycyrrhetic acid + NADP+ = 3-ketoglycyrrhetic acid + NADPH
show the reaction diagram
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(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH
show the reaction diagram
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quinic acid + NAD(P)+ = dehydroquinic acid + NAD(P)H + H+
show the reaction diagram
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6-endo-hydroxycineole + NAD(P)+ = 6-oxocineole + NAD(P)H
show the reaction diagram
-
glycolate + NADP+ = glyoxylate + NADPH + H+
show the reaction diagram
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dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-D-glucose + NADPH
show the reaction diagram
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(S)-lactate + NAD(P)+ = pyruvate + NAD(P)H + H+
show the reaction diagram
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an (R)-2-hydroxycarboxylate + NADP+ = a 2-oxocarboxylate + NADPH + H+
show the reaction diagram
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2-dehydro-D-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
show the reaction diagram
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L-serine + NADP+ = 2-aminomalonate semialdehyde + NADPH
show the reaction diagram
- , 639083
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3beta-hydroxy-5beta-pregnane-20-one + NADP+ = 5beta-pregnane-3,20-dione + NADPH
show the reaction diagram
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GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H
show the reaction diagram
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(S)-lactaldehyde + NADP+ = methylglyoxal + NADPH + H+
show the reaction diagram
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S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+
show the reaction diagram
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D-arabitinol + NADP+ = D-xylulose + NADPH + H+
show the reaction diagram
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1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + NADPH
show the reaction diagram
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71-hydroxychlorophyllide a + NADP+ = chlorophyllide b + NADPH + H+
show the reaction diagram
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(S)-benzoin + NADP+ = benzil + NADPH + H+
show the reaction diagram
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(R)-benzoin + NADP+ = benzil + NADPH + H+
show the reaction diagram
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(-)-endo-fenchol + NAD(P)+ = (+)-fenchone + NAD(P)H + H+
show the reaction diagram
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(+)-thujan-3-ol + NAD(P)+ = (+)-thujan-3-one + NAD(P)H + H+
show the reaction diagram
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(R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
show the reaction diagram
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2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
show the reaction diagram
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vestitone + NADP+ = 7,2'-dihydroxy-4'-methoxyisoflavanol + NADPH + H+
show the reaction diagram
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6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+
show the reaction diagram
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5'-hydroxyaverantin + NADP+ = 5'-oxoaverantin + NADPH + H+
show the reaction diagram
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