Reference on EC 4.1.1.15 - glutamate decarboxylase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Denner, L.A.; Wei, S.C.; Lin, H.S.; Lin, C.T.; Wu, J.Y.
Brain L-glutamate decarboxylase: purification and subunit structure
Proc. Natl. Acad. Sci. USA
84
668-672
1987
Rattus norvegicus
Matsumoto, T.; Yamaura, I.; Funatsu, M.
Purification and properties of glutamate decarboxylase from squash
Agric. Biol. Chem.
50
1413-1417
1986
Cucurbita maxima
-
Fonda, M.L.
L-Glutamate decarboxylase from bacteria
Methods Enzymol.
113
11-16
1985
Clostridium perfringens, Escherichia coli
Wu, J.Y.; Denner, L.; Lin, C.T.; Song, G.
L-Glutamate decarboxylase from brain
Methods Enzymol.
113
3-10
1985
Rattus norvegicus
Spink, D.C.; Porter, T.G.; Wu, S.J.; Martin, D.L.
Characterization of three kinetically distinct forms of glutamate decarboxylase from pig brain
Biochem. J.
231
695-703
1985
Sus scrofa
Satyanarayan, V.; Nair, P.M.
Purification and characterization of glutamate decarboxylase from Solanum tuberosum
Eur. J. Biochem.
150
53-60
1985
Solanum tuberosum
Prabhakaran, K.; Harris, E.B.; Kirchheimer, W.F.
Glutamic acid decarboxylase in Mycobacterium leprae
Arch. Microbiol.
134
320-323
1983
Mycobacterium leprae
Fields, H.A.; Wheeler, C.M.; Davis, C.L.; Warner, T.N.; Bradley, D.W.; Maynard, J.E.
Purification and radiometric assay detection of glutamate decarboxylase
J. Appl. Biochem.
4
271-279
1982
Escherichia coli
-
Wu, J.Y.
Purification and characterization of cysteic acid and cysteine sulfinic acid decarboxylase and L-glutamate decarboxylase from bovine brain
Proc. Natl. Acad. Sci. USA
79
4270-4274
1982
Bos taurus
Blindermann, J.M.; Maitre, M.; Ossola, L.; Mandel, P.
Purification and some properties of L-glutamate decarboxylase from human brain
Eur. J. Biochem.
86
143-152
1978
Homo sapiens
Yamaguchi, T.; Matsumura, Y.
Purification of L-glutamate decarboxylase by affinity chromatography
Biochim. Biophys. Acta
481
706-711
1977
Rattus norvegicus
Inatomi, K.; Slaughter, J.C.
Glutamate decarboxylase from barley embryos and roots
Biochem. J.
147
479-484
1975
Hordeum vulgare
Wu, J.Y.; Matsuda, T.; Roberts, E.
Purification and characterization of glutamate decarboxylase from mouse brain
J. Biol. Chem.
248
3029-3034
1973
Mus musculus
Roberts, E.; Frankel, S.
Further studies of glutamic acid decarboxylase in brain
J. Biol. Chem.
190
505-512
1951
Mus musculus
Johnson, B.S.; Singh, N.K.; Cherry, J.H.; Locy, R.D.
Purification and characterization of glutamate decarboxylase from cowpea
Phytochemistry
46
39-44
1997
Vigna unguiculata
-
Matsumoto, T.; Yamaura, I.; Funatsu, M.
Physical properties of glutamate decarboxylase from squash
Agric. Biol. Chem.
54
3001-3003
1990
Cucurbita maxima
-
Turano, F.J.; Fang, T.K.
Characterization of two glutamate decarboxylase cDNA clones from Arabidopsis
Plant Physiol.
117
1411-1421
1998
Arabidopsis sp.
Chu, W.C.; Metzler, D.E.
Enzymatically active truncated cat brain glutamate decarboxylase: expression, purification, and absorption spectrum
Arch. Biochem. Biophys.
313
287-295
1994
Felis catus
Nathan, B.; Hsu, C.C.; Bao, J.; Wu, R.; Wu, J.Y.
Purification and characterization of a novel form of brain L-glutamate decarboxylase. A Ca2+-dependent peripheral membrane protein
J. Biol. Chem.
269
7249-7254
1994
Sus scrofa
Hao, R.; Schmit, J.C.
Purification and characterization of glutamate decarboxylase from Neurospora crassa conidia
J. Biol. Chem.
266
5135-5139
1991
Neurospora crassa
Bao, J.; Cheung, W.Y.; Wu, J.Y.
Brain L-glutamate decarboxylase. Inhibition by phosphorylation and activation by dephosphorylation
J. Biol. Chem.
270
6464-6467
1995
Sus scrofa
Youngs, T.L.; Tunnicliff, G.
Substrate analogues and divalent cations as inhibitors of glutamate decarboxylase from Escherichia coli
Biochem. Int.
23
915-922
1991
Escherichia coli, Mus musculus
Yun, S.J.; Oh, S.H.
Cloning and characterization of a tobacco cDNA encoding calcium/calmodulin-dependent glutamate decarboxylase
Mol. Cells
8
125-129
1998
Nicotiana tabacum
Ueno, Y.; Hayakawa, K.; Takahashi, S.; Oda, K.
Purification and characterization of glutamate decarboxylase from Lactobacillus brevis IFO 12005
Biosci. Biotechnol. Biochem.
61
1168-1171
1997
Levilactobacillus brevis
Tunnicliff, G.
Action of inhibitors on brain glutamate decarboxylase
Int. J. Biochem.
27
1235-1241
1990
Gallus gallus, Mus musculus, Rattus norvegicus, Sus scrofa
Martin, D.L.; Martin, S.B.; Wu, S.J.; Espina, N.
Regulatory properties of brain glutamate decarboxylase (GAD): the apoenzyme of GAD is present principally as the smaller of two molecular forms of GAD in brain
J. Neurosci.
11
2725-2731
1991
Rattus norvegicus
Bertoldi, M.; Carbone, V.; Borri Voltattorni, C.
Ornithine and glutamate decarboxylases catalyze an oxidative deamination of their a-methyl substrates
Biochem. J.
342
509-512
1999
Escherichia coli
-
McCormick, S.J.; Tunnicliff, G.
Kinetics of inactivation of glutamate decarboxylase by cysteine-specific reagents
Acta Biochim. Pol.
48
573-578
2001
Escherichia coli
Strigacova, J.; Chovanec, P.; Liptaj, T.; Hudecova, D.; Tursky, T.; Simkovic, M.; Varecka, L.
Glutamate decarboxylase activity in Trichoderma viride conidia and developing mycelia
Arch. Microbiol.
175
32-40
2001
Trichoderma viride
Davis, K.M.; Foos, T.; Bates, C.S.; Tucker, E.; Hsu, C.C.; Chen, W.; Jin, H.; Tyburski, J.B.; Schloss, J.V.; Tobin, A.J.; Wu, J.Y.
A novel method for expression and large-scale production of human brain l-glutamate decarboxylase
Biochem. Biophys. Res. Commun.
267
777-782
2000
Homo sapiens
Chen, C.H.; Battaglioli, G.; Martin, D.L.; Hobart, S.A.; Colon, W.
Distinctive interactions in the holoenzyme formation for two isoforms of glutamate decarboxylase
Biochim. Biophys. Acta
1645
63-71
2003
Rattus norvegicus
Primo, M.E.; Anton, E.A.; Villanueva, A.L.; Poskus, E.; Ermacora, M.R.
Engineered variants of human glutamic acid decarboxylase (GAD) and autoantibody epitope recognition
Clin. Immunol.
108
38-45
2003
Homo sapiens
Capitani, G.; De Biase, D.; Aurizi, C.; Gut, H.; Bossa, F.; Grutter, M.G.
Crystal structure and functional analysis of Escherichia coli glutamate decarboxylase
EMBO J.
22
4027-4037
2003
Escherichia coli
Papakonstantinou, T.; Law, R.H.P.; Gardiner, P.; Rowley, M.J.; Mackay, I.R.
Comparative expression and purification of human glutamic acid decarboxylase from Saccharomyces cerevisiae and Pichia pastoris
Enzyme Microb. Technol.
26
645-652
2000
Homo sapiens
Tursky, T.; Bandzuchova, E.
An endogenous activator of renal glutamic acid decarboxylase effects of adenosine triphosphate, phosphate and chloride on the activity of this enzyme
Eur. J. Biochem.
262
696-703
1999
Rattus norvegicus
Liu, W.H.; Wang, C.L.
Culture conditions and some properties of glutamate decarboxylase produced by Monascus purpureus
Food Sci. Agric. Chem.
4
15-19
2002
Monascus purpureus
-
Tsuchiya, K.; Nishimura, K.; Iwahara, M.
Purification and characterization of glutamate decarboxylase from Aspergillus oryzae
Food Sci. Technol. Res.
9
283-287
2003
Aspergillus oryzae
-
Kanaani, J.; Lissin, D.; Kash, S.F.; Baekkeskov, S.
The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65
J. Biol. Chem.
274
37200-37209
1999
Rattus norvegicus
Hsu, C.C.; Davis, K.M.; Jin, H.; Foos, T.; Floor, E.; Chen, W.; Tyburski, J.B.; Yang, C.Y.; Schloss, J.V.; Wu, J.Y.
Association of L-glutamic acid decarboxylase to the 70-kDa heat shock protein as a potential anchoring mechanism to synaptic vesicles
J. Biol. Chem.
275
20822-20828
2000
Sus scrofa
Davis, K.; Foos, T.; Wu, J.Y.; Schloss, J.V.
Oxygen-induced seizures and inhibition of human glutamate decarboxylase and porcine cysteine sulfinic acid decarboxylase by oxygen and nitric oxide
J. Biomed. Sci.
8
359-364
2001
Homo sapiens
Tong, J.C.; Mackay, I.R.; Chin, J.; Law, R.H.; Fayad, K.; Rowley, M.J.
Enzymatic characterization of a recombinant isoform hybrid of glutamic acid decarboxylase (rGAD67/65) expressed in yeast
J. Biotechnol.
97
183-190
2002
Homo sapiens
Buss, K.; Drewke, C.; Lohmann, S.; Piwonska, A.; Leistner, E.
Properties and interaction of heterologously expressed glutamate decarboxylase isoenzymes GAD(65kDa) and GAD(67kDa) from human brain with ginkgotoxin and its 5'-phosphate
J. Med. Chem.
44
3166-3174
2001
Homo sapiens
Zanone, M.M.; Catalfamo, E.; Pietropaolo, S.L.; Rabbone, I.; Sacchetti, C.; Cerutti, F.; Trucco, M.; Cavallo-Perin, P.
Glutamic acid decarboxylase and ICA512/IA-2 autoantibodies as disease markers and relationship to residual beta-cell function and glycemic control in young type 1 diabetic patients
Metabolism
52
25-29
2003
Homo sapiens
Martin, D.L.; Liu, H.; Martin, S.B.; Wu, S.J.
Structural features and regulatory properties of the brain glutamate decarboxylases
Neurochem. Int.
37
111-119
2000
Rattus norvegicus
Drsata, J.; Netopilova, M.; Tolman, V.
Stereoisomers of 4-fluoroglutamic acid. Influence on Escherichia coli glutamate decarboxylase
Pharmazie
54
713-714
1999
Escherichia coli
Dutyshev, D.I.; Darii, E.L.; Fomenkova, N.P.; Pechik, I.V.; Polyakov, K.M.; Nikonov, S.V.; Andreeva, N.S.; Sukhareva, B.S.
Structure of Escherichia coli glutamate decarboxylase (GADalpha) in complex with glutarate at 2.05 A resolution
Acta Crystallogr. Sect. D
61
230-235
2005
Escherichia coli
Lappalainen, J.; Sanacora, G.; Kranzler, H.R.; Malison, R.; Hibbard, E.S.; Price, L.H.; Krystal, J.; Gelernter, J.
Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression
Am. J. Med. Genet.
124
81-86
2004
Homo sapiens
Cotter, P.D.; Ryan, S.; Gahan, C.G.; Hill, C.
Presence of GadD1 glutamate decarboxylase in selected Listeria monocytogenes strains is associated with an ability to grow at low pH
Appl. Environ. Microbiol.
71
2832-2839
2005
Listeria monocytogenes, Listeria monocytogenes LO28
Wei, J.; Davis, K.M.; Wu, H.; Wu, J.Y.
Protein phosphorylation of human brain glutamic acid decarboxylase (GAD)65 and GAD67 and its physiological implications
Biochemistry
43
6182-6189
2004
Homo sapiens
Park, K.B.; Ji, G.E.; Park, M.S.; Oh, S.H.
Expression of rice glutamate decarboxylase in Bifidobacterium longum enhances gamma-aminobutyric acid production
Biotechnol. Lett.
27
1681-1684
2005
Oryza sativa
Ricci, L.A.; Grimes, J.M.; Knyshevski, I.; Melloni, R.H.
Repeated cocaine exposure during adolescence alters glutamic acid decarboxylase-65 (GAD65) immunoreactivity in hamster brain: correlation with offensive aggression
Brain Res.
1035
131-138
2005
Mesocricetus auratus
Sha, D.; Wei, J.; Wu, H.; Jin, Y.; Wu, J.Y.
Molecular cloning, expression, purification, and characterization of shorter forms of human glutamic decarboxylase 67 in an E. coli expression system
Brain Res. Mol. Brain Res.
136
255-261
2005
Homo sapiens, Sus scrofa
Oh, S.H.; Choi, W.G.; Lee, I.T.; Yun, S.J.
Cloning and characterization of a rice cDNA encoding glutamate decarboxylase
J. Biochem. Mol. Biol.
38
595-601
2005
Oryza sativa (Q5F1L4), Oryza sativa
Jin, H.; Sha, D.; Wei, J.; Davis, K.M.; Wu, H.; Jin, Y.; Wu, J.Y.
Effect of apocalmodulin on recombinant human brain glutamic acid decarboxylase
J. Neurochem.
92
739-748
2005
Homo sapiens
Battaglioli, G.; Liu, H.; Hauer, C.R.; Martin, D.L.
Glutamate decarboxylase: loss of N-terminal segment does not affect homodimerization and determination of the oxidation state of cysteine residues
Neurochem. Res.
30
989-1001
2005
Rattus norvegicus
Ma, S.; Huang, Y.; Yin, Z.; Menassa, R.; Brandle, J.E.; Jevnikar, A.M.
Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4
Proc. Natl. Acad. Sci. USA
101
5680-5685
2004
Homo sapiens
Wang, F.Y.; Watanabe, M.; Zhu, R.M.; Maemura, K.
Characteristic expression of gamma-aminobutyric acid and glutamate decarboxylase in rat jejunum and its relation to differentiation of epithelial cells
World J. Gastroenterol.
10
3608-3611
2004
Rattus norvegicus
Martyniuk, C.J.; Awad, R.; Hurley, R.; Finger, T.E.; Trudeau, V.L.
Glutamic acid decarboxylase 65, 67, and GABA-transaminase mRNA expression and total enzyme activity in the goldfish (Carassius auratus) brain
Brain Res.
1147
154-166
2007
Carassius auratus
Martyniuk, C.J.; Chang, J.P.; Trudeau, V.L.
The effects of GABA agonists on glutamic acid decarboxylase, GABA-transaminase, activin, salmon gonadotrophin-releasing hormone and tyrosine hydroxylase mRNA in the goldfish (Carassius auratus) neuroendocrine brain
J. Neuroendocrinol.
19
390-396
2007
Carassius auratus
Liu, C.P.
Glutamic acid decarboxylase-specific CD4+ regulatory T cells
Ann. N. Y. Acad. Sci.
1079
161-170
2006
Mus musculus
Zik, M.; Fridmann-Sirkis, Y.; Fromm, H.
C-terminal residues of plant glutamate decarboxylase are required for oligomerization of a high-molecular weight complex and for activation by calcium/calmodulin
Biochim. Biophys. Acta
1764
872-876
2006
Petunia sp.
Park, K.B.; Oh, S.H.
Enhancement of gamma-aminobutyric acid production in Chungkukjang by applying a Bacillus subtilis strain expressing glutamate decarboxylase from Lactobacillus brevis
Biotechnol. Lett.
28
1459-1463
2006
Levilactobacillus brevis
Wu, H.; Jin, Y.; Buddhala, C.; Osterhaus, G.; Cohen, E.; Jin, H.; Wei, J.; Davis, K.; Obata, K.; Wu, J.Y.
Role of glutamate decarboxylase (GAD) isoform, GAD65, in GABA synthesis and transport into synaptic vesicles - Evidence from GAD65-knockout mice studies
Brain Res.
1154
80-83
2007
Mus musculus
Sardana, R.K.; Awad, R.; Arnason, J.T.; Trudeau, V.L.
Expression of recombinant goldfish glutamic acid decarboxylase 65 and evidence for differential pH and PLP responsiveness compared to the human enzyme
Comp. Biochem. Physiol. B
144B
94-100
2006
Carassius auratus, Homo sapiens
-
Zhang, H.; Yao, H.; Chen, F.; Wang, X.
Purification and characterization of glutamate decarboxylase from rice germ
Food Chem.
101
1670-1676
2006
Oryza sativa
-
Zhang, H.; Yao, H.; Chen, F.; Wang, X.
Some molecular properties of glutamate decarboxylase from rice germ
Food Chem.
105
65-71
2007
Oryza sativa
Matsukawa, S.; Ueno, H.
Expression of glutamate decarboxylase isoform, GAD65, in human mononuclear leucocytes: a possible implication of C-terminal end deletion by Western blot and RT PCR study
J. Biochem.
142
633-638
2007
Homo sapiens
Akama, K.; Takaiwa, F.
C-terminal extension of rice glutamate decarboxylase (OsGAD2) functions as an autoinhibitory domain and overexpression of a truncated mutant results in the accumulation of extremely high levels of GABA in plant cells
J. Exp. Bot.
58
2699-2707
2007
Oryza sativa (Q9AR41), Oryza sativa
Matthews, C.C.; Zielke, H.R.; Fishman, P.S.; Remington, M.P.; Bowen, T.G.
Glutamate decarboxylase protects neurons against excitotoxic injury
J. Neurosci. Res.
85
855-859
2007
Escherichia coli
Fenalti, G.; Law, R.H.; Buckle, A.M.; Langendorf, C.; Tuck, K.; Rosado, C.J.; Faux, N.G.; Mahmood, K.; Hampe, C.S.; Banga, J.P.; Wilce, M.; Schmidberger, J.; Rossjohn, J.; El-Kabbani, O.; Pike, R.N.; Smith, A.I.; Mackay, I.R.; Rowley, M.J.; Whisstock, J.C.
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
Nat. Struct. Mol. Biol.
14
280-286
2007
Homo sapiens
Fisher, R.S.
Co-localization of glutamic acid decarboxylase and phosphate-activated glutaminase in neurons of lateral reticular nucleus in feline thalamus
Neurochem. Res.
32
177-186
2007
Felis catus
Freichel, C.; Potschka, H.; Ebert, U.; Brandt, C.; Loescher, W.
Acute changes in the neuronal expression of GABA and glutamate decarboxylase isoforms in the rat piriform cortex following status epilepticus
Neuroscience
141
2177-2194
2006
Rattus norvegicus
Park, J.S.; Han, K.Y.; Lee, J.H.; Song, J.A.; Ahn, K.Y.; Seo, H.S.; Sim, S.J.; Kim, S.W.; Lee, J.
Solubility enhancement of aggregation-prone heterologous proteins by fusion expression using stress-responsive Escherichia coli protein, RpoS
BMC Biotechnol.
8
15
2008
Homo sapiens
Wegner, N.; Wait, R.; Venables, P.J.
Evolutionarily conserved antigens in autoimmune disease: Implications for an infective aetiology
Int. J. Biochem. Cell Biol.
41
390-397
2008
Homo sapiens
Villalba, A.; Iacono, R.F.; Valdez, S.N.; Poskus, E.
Detection and immunochemical characterization of glutamic acid decarboxylase autoantibodies in patients with autoimmune diabetes mellitus
Autoimmunity
41
143-153
2008
Homo sapiens
Obata, K.; Hirono, M.; Kume, N.; Kawaguchi, Y.; Itohara, S.; Yanagawa, Y.
GABA and synaptic inhibition of mouse cerebellum lacking glutamate decarboxylase 67
Biochem. Biophys. Res. Commun.
370
429-433
2008
Mus musculus
Hiraga, K.; Ueno, Y.; Oda, K.
Glutamate decarboxylase from Lactobacillus brevis: activation by ammonium sulfate
Biosci. Biotechnol. Biochem.
72
1299-1306
2008
Levilactobacillus brevis (A9ZM78), Levilactobacillus brevis, Levilactobacillus brevis IFO 12005 (A9ZM78)
Inoue, Y.; Ishii, K.; Miyazaki, M.; Ueno, H.
Purification of L-glutamate decarboxylase from monkey brain
Biosci. Biotechnol. Biochem.
72
2269-2276
2008
Macaca fuscata
Komatsuzaki, N.; Nakamura, T.; Kimura, T.; Shima, J.
Characterization of glutamate decarboxylase from a high gamma-aminobutyric acid (GABA)-producer, Lactobacillus paracasei
Biosci. Biotechnol. Biochem.
72
278-285
2008
Lacticaseibacillus paracasei (B1B389), Lacticaseibacillus paracasei, Lacticaseibacillus paracasei NFRI 7415 (B1B389)
Kim, H.W.; Kashima, Y.; Ishikawa, K.; Yamano, N.
Purification and characterization of the first archaeal glutamate decarboxylase from Pyrococcus horikoshii
Biosci. Biotechnol. Biochem.
73
224-227
2009
Pyrococcus horikoshii
Sha, D.; Jin, Y.; Wu, H.; Wei, J.; Lin, C.H.; Lee, Y.H.; Buddhala, C.; Kuchay, S.; Chishti, A.H.; Wu, J.Y.
Role of mu-calpain in proteolytic cleavage of brain L-glutamic acid decarboxylase
Brain Res.
1207
9-18
2008
Homo sapiens, Mus musculus, Rattus norvegicus
Saiz, A.; Blanco, Y.; Sabater, L.; Gonzalez, F.; Bataller, L.; Casamitjana, R.; Ramio-Torrenta, L.; Graus, F.
Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association
Brain
131
2553-2563
2008
Homo sapiens
Rahmati, K.; Lernmark, A.; Becker, C.; Foltyn-Zadura, A.; Larsson, K.; Ivarsson, S.A.; Toern, C.
A comparison of serum and EDTA plasma in the measurement of glutamic acid decarboxylase autoantibodies (GADA) and autoantibodies to islet antigen-2 (IA-2A) using the RSR radioimmunoassay (RIA) and enzyme linked immunosorbent assay (ELISA) kits
Clin. Lab.
54
227-235
2008
Homo sapiens
Markakis, I.; Alexiou, E.; Xifaras, M.; Gekas, G.; Rombos, A.
Opsoclonus-myoclonus-ataxia syndrome with autoantibodies to glutamic acid decarboxylase
Clin. Neurol. Neurosurg.
110
619-621
2008
Homo sapiens
Toern, C.; Mueller, P.W.; Schlosser, M.; Bonifacio, E.; Bingley, P.J.; Bingley, P.J.
Diabetes antibody standardization program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2
Diabetologia
51
846-852
2008
Homo sapiens
Schlosser, M.; Walschus, U.; Kloeting, I.; Walther, R.
Determination of glutamic acid decarboxylase (GAD65) in pancreatic islets and its in vitro and in vivo degradation kinetics in serum using a highly sensitive enzyme immunoassay
Dis. Markers
24
191-198
2008
Homo sapiens, Mus musculus, Rattus norvegicus, Rattus norvegicus LEW-1A, Sus scrofa
Kuo, P.H.; Kalsi, G.; Prescott, C.A.; Hodgkinson, C.A.; Goldman, D.; Alexander, J.; van den Oord, E.J.; Chen, X.; Sullivan, P.F.; Patterson, D.G.; Walsh, D.; Kendler, K.S.; Riley, B.P.
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the irish affected Sib pair study of alcohol dependence
Drug Alcohol Depend.
101
80-87
2008
Homo sapiens
Yoshihara, A.; Isozaki, O.; Okubo, Y.; Takano, K.
Anti-glutamic acid decarboxylase antibody in Graves' disease is a possible indicator for the unlikelihood of going into remission with antithyroid agents
Endocr. J.
56
269-274
2009
Homo sapiens
Monnerie, H.; Le Roux, P.D.
Glutamate alteration of glutamic acid decarboxylase (GAD) in GABAergic neurons: the role of cysteine proteases
Exp. Neurol.
213
145-153
2008
Mus musculus, Mus musculus BALB/c
Davies, H.; Mannan, S.; Brophy, S.; Williams, R.
Routine glutamic acid decarboxylase autoantibody (GADA) testing: patients perspective
Fam. Pract.
25
176-180
2008
Homo sapiens
Gos, T.; Guenther, K.; Bielau, H.; Dobrowolny, H.; Mawrin, C.; Truebner, K.; Brisch, R.; Steiner, J.; Bernstein, H.G.; Jankowski, Z.; Bogerts, B.
Suicide and depression in the quantitative analysis of glutamic acid decarboxylase-immunoreactive neuropil
J. Affect. Disord.
113
45-55
2009
Homo sapiens
Skorstad, G.; Hestvik, A.L.; Vartdal, F.; Holmoy, T.
Cerebrospinal fluid T cell responses against glutamic acid decarboxylase 65 in patients with stiff person syndrome
J. Autoimmun.
32
24-32
2008
Homo sapiens
Luo, Y.; Lathia, J.; Mughal, M.; Mattson, M.P.
SDF1alpha/CXCR4 signaling, via ERKs and the transcription factor Egr1, induces expression of a 67-kDa form of glutamic acid decarboxylase in embryonic hippocampal neurons
J. Biol. Chem.
283
24789-24800
2008
Rattus norvegicus
Yang, S.; Lin, Q.; Lu, Z.; Lu, F.; Bie, X.; Zou, X.; Sun, L.
Characterization of a novel glutamate decarboxylase from Streptococcus salivarius ssp. thermophilus Y2
J. Chem. Technol. Biotechnol.
83
855-861
2008
Streptococcus thermophilus (Q0GE18)
-
Ledet, D.S.; Handgretinger, R.; Bertorini, T.E.; Hale, G.A.; Ribeiro, R.C.; Khan, R.B.
Leucoencephalopathy, transverse myelopathy, and peripheral neuropathy in association with glutamic acid decarboxylase-65 (GAD) antibodies in children with cancer
J. Child Neurol.
23
1357-1362
2008
Homo sapiens
Steed, J.; Gilliam, L.K.; Harris, R.A.; Lernmark, A.; Hampe, C.S.
Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein
J. Immunol. Methods
334
114-121
2008
Homo sapiens
Buttenschoen, H.N.; Lauritsen, M.B.; Daoud, A.E.; Hollegaard, M.; Jorgensen, M.; Tvedegaard, K.; Hougaard, D.; Boerglum, A.; Thorsen, P.; Mors, O.
A population-based association study of glutamate decarboxylase 1 as a candidate gene for autism
J. Neural Transm.
116
381-388
2009
Homo sapiens
Mata, S.; Muscas, G.C.; Naldi, I.; Rosati, E.; Paladini, S.; Cruciatti, B.; Bisulli, F.; Paganini, M.; Mazzi, G.; Sorbi, S.; Tinuper, P.
Non-paraneoplastic limbic encephalitis associated with anti-glutamic acid decarboxylase antibodies
J. Neuroimmunol.
199
155-159
2008
Homo sapiens
Ishida, K.; Mitoma, H.; Mizusawa, H.
Reversibility of cerebellar GABAergic synapse impairment induced by anti-glutamic acid decarboxylase autoantibodies
J. Neurol. Sci.
271
186-190
2008
Homo sapiens
Hill, L.E.; Droste, S.K.; Nutt, D.J.; Linthorst, A.C.; Reul, J.M.
Voluntary exercise alters GABAA receptor subunit and glutamic acid decarboxylase-67 gene expression in the rat forebrain
J. Psychopharmacol. (Oxford)
24
745-756
2010
Rattus norvegicus
Hwang, I.K.; Yoo, K.Y.; Li, H.; Park, O.K.; Lee, C.H.; Choi, J.H.; Kwon, D.Y.; Won, M.H.
Transient increases of glutamic acid decarboxylase 67 immunoreactivity and its protein levels in the somatosensory cortex after transient cerebral ischemia in gerbils
J. Vet. Med. Sci.
70
1005-1010
2008
Meriones unguiculatus
Arata, S.; Hashizume, C.; Kikusui, T.; Takeuchi, Y.; Mori, Y.
Sequences of canine glutamate decarboxylase (GAD) 1 and GAD2 genes, and variation of their genetic polymorphisms among five dog breeds
J. Vet. Med. Sci.
70
1107-1110
2008
Canis lupus familiaris, Canis lupus familiaris (Q4PRC2)
Bergado-Acosta, J.R.; Sangha, S.; Narayanan, R.T.; Obata, K.; Pape, H.C.; Stork, O.
Critical role of the 65-kDa isoform of glutamic acid decarboxylase in consolidation and generalization of Pavlovian fear memory
Learn. Mem.
15
163-171
2008
Mus musculus
Liu, H.; Wang, Z.; Li, S.; Zhang, Y.; Yan, Y.C.; Li, Y.P.
Utilization of an intron located polyadenlyation site resulted in four novel glutamate decarboxylase transcripts
Mol. Biol. Rep.
36
1469-1474
2008
Rattus norvegicus
Wei, J.; Wu, J.Y.
Post-translational regulation of L-glutamic acid decarboxylase in the brain
Neurochem. Res.
33
1459-1465
2008
Mus musculus, Rattus norvegicus, Homo sapiens (Q05329), Homo sapiens (Q99259)
Hwang, I.K.; Li, H.; Yoo, K.; Choi, J.H.; Lee, C.H.; Chung, D.W.; Kim, D.W.; Seong, J.K.; Yoon, Y.S.; Lee, I.S.; Won, M.
Comparison of glutamic acid decarboxylase 67 immunoreactive neurons in the hippocampal CA1 region at various age stages in dogs
Neurosci. Lett.
431
251-255
2008
Canis lupus familiaris
Nishimura, K.; Kitamura, Y.; Umesono, Y.; Takeuchi, K.; Takata, K.; Taniguchi, T.; Agata, K.
Identification of glutamic acid decarboxylase gene and distribution of GABAergic nervous system in the planarian Dugesia japonica
Neuroscience
153
1103-1114
2008
Dugesia japonica, Dugesia japonica SSP
Yamamoto, N.; Soghomonian, J.
Time-course of SKF-81297-induced increase in glutamic acid decarboxylase 65 and 67 mRNA levels in striatonigral neurons and decrease in GABAA receptor alpha 1 subunit mRNA levels in the substantia nigra, pars reticulata, in adult rats with a unilateral 6-hydroxydopamine lesion
Neuroscience
154
1088-1099
2008
Rattus norvegicus
Alonso-Espinaco, V.; Elezgarai, I.; Diez-Garcia, J.; Puente, N.; Knoepfel, T.; Grandes, P.
Subcellular localization of the voltage-gated potassium channels Kv3.1b and Kv3.3 in the cerebellar dentate nucleus of glutamic acid decarboxylase 67-green fluorescent protein transgenic mice
Neuroscience
155
1059-1069
2008
Mus musculus, Mus musculus C57BL/6
El Idrissi, A.; L'Amoreaux, W.J.
Selective resistance of taurine-fed mice to isoniazide-potentiated seizures: In vivo functional test for the activity of glutamic acid decarboxylase
Neuroscience
156
693-699
2008
Mus musculus (P48320)
Kaneko, K.; Tamamaki, N.; Owada, H.; Kakizaki, T.; Kume, N.; Totsuka, M.; Yamamoto, T.; Yawo, H.; Yagi, T.; Obata, K.; Yanagawa, Y.
Noradrenergic excitation of a subpopulation of GABAergic cells in the basolateral amygdala via both activation of nonselective cationic conductance and suppression of resting K+ conductance: A study using glutamate decarboxylase 67-green fluorescent prote
Neuroscience
157
781-797
2008
Mus musculus
Awad, R.; Crump, K.; Mullally, M.; Sardana, R.K.; Arnason, J.T.; Trudeau, V.L.
An improved method for production of recombinant human glutamic acid decarboxylase 65 for use in phytopharmaceutical assessment
Pharm. Biol.
46
72-81
2008
Homo sapiens
-
El-Faramawy, Y.A.; El-Banouby, M.H.; Sergeev, P.; Mortagy, A.K.; Amer, M.S.; Abdel-Tawab, A.M.
Changes in glutamate decarboxylase enzyme activity and tau-protein phosphorylation in the hippocampus of old rats exposed to chronic mild stress: Reversal with the neuronal nitric oxide synthase inhibitor 7-nitroindazole
Pharmacol. Biochem. Behav.
91
339-344
2009
Rattus norvegicus
Satta, R.; Maloku, E.; Zhubi, A.; Pibiri, F.; Hajos, M.; Costa, E.; Guidotti, A.
Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons
Proc. Natl. Acad. Sci. USA
105
16356-16361
2008
Homo sapiens, Mus musculus
Oak, S.; Gilliam, L.K.; Landin-Olsson, M.; Toern, C.; Kockum, I.; Pennington, C.R.; Rowley, M.J.; Christie, M.R.; Banga, J.P.; Hampe, C.S.
The lack of anti-idiotypic antibodies, not the presence of the corresponding autoantibodies to glutamate decarboxylase, defines type 1 diabetes
Proc. Natl. Acad. Sci. USA
105
5471-5476
2008
Homo sapiens
Liu, H.; Li, S.; Zhang, Y.; Yan, Y.; Li, Y.
Dynamic regulation of glutamic acid decarboxylase 65 gene expression in rat testis
Acta Biochim. Biophys. Sin.
41
545-553
2009
Rattus norvegicus
Arunchaipong, K.; Sattayasai, N.; Sattayasai, J.; Svasti, J.; Rimlumduan, T.
A biotin-coupled bifunctional enzyme exhibiting both glutamine synthetase activity and glutamate decarboxylase activity
Curr. Eye Res.
34
809-818
2009
Gallus gallus
Liimatainen, S.; Peltola, M.; Sabater, L.; Fallah, M.; Kharazmi, E.; Haapala, A.M.; Dastidar, P.; Knip, M.; Saiz, A.; Peltola, J.
Clinical significance of glutamic acid decarboxylase antibodies in patients with epilepsy
Epilepsia
51
760-767
2010
Homo sapiens
Alonso-Hernando, A.; Alonso-Calleja, C.; Capita, R.
Comparative analysis of acid resistance in Listeria monocytogenes and Salmonella enterica strains before and after exposure to poultry decontaminants. Role of the glutamate decarboxylase (GAD) system
Food Microbiol.
26
905-909
2009
Salmonella enterica, Listeria monocytogenes
Miyazato, M.; Sugaya, K.; Goins, W.F.; Wolfe, D.; Goss, J.R.; Chancellor, M.B.; de Groat, W.C.; Glorioso, J.C.; Yoshimura, N.
Herpes simplex virus vector-mediated gene delivery of glutamic acid decarboxylase reduces detrusor overactivity in spinal cord-injured rats
Gene Ther.
16
660-668
2009
Rattus norvegicus
Pennacchietti, E.; Lammens, T.M.; Capitani, G.; Franssen, M.C.; John, R.A.; Bossa, F.; De Biase, D.
Mutation of His465 alters the pH-dependent spectroscopic properties of Escherichia coli glutamate decarboxylase and broadens the range of its activity toward more alkaline pH
J. Biol. Chem.
284
31587-31596
2009
Escherichia coli (P69910), Escherichia coli
Matsuyama, A.; Yoshimura, K.; Shimizu, C.; Murano, Y.; Takeuchi, H.; Ishimoto, M.
Characterization of glutamate decarboxylase mediating gamma-amino butyric acid increase in the early germination stage of soybean (Glycine max [L.] Merr)
J. Biosci. Bioeng.
107
538-543
2009
Glycine max (Q7XJB3), Glycine max
Gut, H.; Dominici, P.; Pilati, S.; Astegno, A.; Petoukhov, M.V.; Svergun, D.I.; Gruetter, M.G.; Capitani, G.
A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase
J. Mol. Biol.
392
334-351
2009
Arabidopsis thaliana (Q42521), Arabidopsis thaliana
Sangha, S.; Narayanan, R.T.; Bergado-Acosta, J.R.; Stork, O.; Seidenbecher, T.; Pape, H.C.
Deficiency of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory
J. Neurosci.
29
15713-15720
2009
Mus musculus
Kubo, K.; Nishikawa, K.; Hardy-Yamada, M.; Ishizeki, J.; Yanagawa, Y.; Saito, S.
Altered responses to propofol, but not ketamine, in mice deficient in the 65-kilodalton isoform of glutamate decarboxylase
J. Pharmacol. Exp. Ther.
329
592-599
2009
Mus musculus
Kubo, K.; Nishikawa, K.; Ishizeki, J.; Hardy-Yamada, M.; Yanagawa, Y.; Saito, S.
Thermal hyperalgesia via supraspinal mechanisms in mice lacking glutamate decarboxylase 65
J. Pharmacol. Exp. Ther.
331
162-169
2009
Mus musculus
Thompson, M.; Weickert, C.S.; Wyatt, E.; Webster, M.J.
Decreased glutamic acid decarboxylase67 mRNA expression in multiple brain areas of patients with schizophrenia and mood disorders
J. Psychiatr. Res.
43
970-977
2009
Homo sapiens (Q99259)
Wang, L.; Xu, D.X.; Lv, Y.G.; Zhang, H.
Purification and biochemical characterisation of a novel glutamate decarboxylase from rice bran
J. Sci. Food Agric.
90
1027-1033
2010
Oryza sativa (Q9AR41), Oryza sativa
Wang, L.; Liu, M.; Lv, Y.G.; Zhang, H.
Purification of calmodulin from rice bran and activation of glutamate decarboxylase by Ca2+/calmodulin
J. Sci. Food Agric.
90
669-675
2010
Oryza sativa
Richardson, G.; Ding, H.; Rocheleau, T.; Mayhew, G.; Reddy, E.; Han, Q.; Christensen, B.M.; Li, J.
An examination of aspartate decarboxylase and glutamate decarboxylase activity in mosquitoes
Mol. Biol. Rep.
37
3199-3205
2009
Anopheles gambiae
Lee, J.H.; Kim, Y.J.; Jeong, D.Y.; Sathiyaraj, G.; Pulla, R.K.; Shim, J.S.; In, J.G.; Yang, D.C.
Isolation and characterization of a glutamate decarboxylase (GAD) gene and their differential expression in response to abiotic stresses from Panax ginseng C. A. Meyer
Mol. Biol. Rep.
37
3455-3463
2009
Panax ginseng
Yamamoto, N.; Soghomonian, J.J.
Metabotropic glutamate mGluR5 receptor blockade opposes abnormal involuntary movements and the increases in glutamic acid decarboxylase mRNA levels induced by l-DOPA in striatal neurons of 6-hydroxydopamine-lesioned rats
Neuroscience
163
1171-1180
2009
Rattus norvegicus
Sivertsen, T.; Nygaard, A.K.; Mathisen, G.; Fonnum, F.
Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice
Toxicol. Mech. Methods
19
214-218
2009
Mus musculus, Mus musculus B6D2
Yao, W.; Wu, X.; Zhu, J.; Sun, B.; Miller, C.
System establishment of ATPS for one-step purification of glutamate decarboxylase from E. coli after cell disruption
Appl. Biochem. Biotechnol.
164
1339-1349
2011
Escherichia coli
Begley, M.; Cotter, P.D.; Hill, C.; Ross, R.P.
Glutamate decarboxylase-mediated nisin resistance in Listeria monocytogenes
Appl. Environ. Microbiol.
76
6541-6546
2010
Lactococcus lactis subsp. lactis, Listeria monocytogenes, no activity in Lactococcus lactis subsp. cremoris, Lactococcus lactis subsp. lactis IL1403, Listeria monocytogenes LO28
Xu, H.; Liao, P.; Xiao, J.; Zhang, Q.; Dong, Y.; Kai, G.
Molecular cloning and characterization of glutamate decarboxylase cDNA from the giant-embryo Oryza sativa
Arch. Biol. Sci.
62
873-879
2010
Oryza sativa
-
Shi, F.; Li, Y.
Synthesis of gamma-aminobutyric acid by expressing Lactobacillus brevis-derived glutamate decarboxylase in the Corynebacterium glutamicum strain ATCC 13032
Biotechnol. Lett.
33
2469-2474
2011
Levilactobacillus brevis, Levilactobacillus brevis Lb85
Yu, K.; Hu, S.; Huang, J.; Mei, L.
A high-throughput colorimetric assay to measure the activity of glutamate decarboxylase
Enzyme Microb. Technol.
49
272-276
2011
Levilactobacillus brevis, Levilactobacillus brevis CGMCC
Kook, M.; Seo, M.; Cheigh, C.; Lee, S.; Pyun, Y.; Park, H.
Enhancement of gamma-amminobutyric acid production by Lactobacillus sakei B2-16 expressing glutamate decarboxylase from Lactobacillus plantarum ATCC 14917
J. Korean Soc. Appl. Biol. Chem.
53
816-820
2010
Lactiplantibacillus plantarum, Lactiplantibacillus plantarum ATCC 14917
-
Raghuraman, G.; Prabhakar, N.R.; Kumar, G.K.
Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling
J. Neurochem.
115
1568-1578
2010
Rattus norvegicus
Zhuang, Y.; Ren, G.; He, C.; Li, X.; Meng, Q.; Zhu, C.; Wang, R.; Zhang, J.
Cloning and characterization of a maize cDNA encoding glutamate decarboxylase
Plant Mol. Biol. Rep.
28
620-626
2010
Zea mays
-
Molina-Rueda, J.J.; Pascual, M.B.; Canovas, F.M.; Gallardo, F.
Characterization and developmental expression of a glutamate decarboxylase from maritime pine
Planta
232
1471-1483
2010
Pinus pinaster (A0EJ89), Pinus pinaster
Wang, Q.; Xin, Y.; Zhang, F.; Feng, Z.; Fu, J.; Luo, L.; Yin, Z.
Enhanced ?-aminobutyric acid-forming activity of recombinant glutamate decarboxylase (gadA) from Escherichia coli
World J. Microbiol. Biotechnol.
27
693-700
2011
Escherichia coli
Fan, E.; Huang, J.; Hu, S.; Mei, L.; Yu, K.
Cloning, sequencing and expression of a glutamate decarboxylase gene from the GABA-producing strain Lactobacillus brevis CGMCC 1306
Ann. Microbiol.
62
689-698
2011
Levilactobacillus brevis (D6PXK5), Levilactobacillus brevis CGMCC 1306 (D6PXK5)
-
Karatzas, K.A.; Suur, L.; OByrne, C.P.
Characterization of the intracellular glutamate decarboxylase system: analysis of its function, transcription, and role in the acid resistance of various strains of Listeria monocytogenes
Appl. Environ. Microbiol.
78
3571-3579
2012
Listeria monocytogenes, Listeria monocytogenes LO28
Seo, M.J.; Nam, Y.D.; Lee, S.Y.; Park, S.L.; Yi, S.H.; Lim, S.I.
Expression and characterization of a glutamate decarboxylase from Lactobacillus brevis 877G producing gamma-aminobutyric acid
Biosci. Biotechnol. Biochem.
77
853-856
2013
Levilactobacillus brevis (K4HXK6), Levilactobacillus brevis 877G (K4HXK6)
Yu, K.; Lin, L.; Hu, S.; Huang, J.; Mei, L.
C-terminal truncation of glutamate decarboxylase from Lactobacillus brevis CGMCC 1306 extends its activity toward near-neutral pH
Enzyme Microb. Technol.
50
263-269
2012
Levilactobacillus brevis, Levilactobacillus brevis CGMCC 1306
Takahashi, C.; Shirakawa, J.; Tsuchidate, T.; Okai, N.; Hatada, K.; Nakayama, H.; Tateno, T.; Ogino, C.; Kondo, A.
Robust production of gamma-amino butyric acid using recombinant Corynebacterium glutamicum expressing glutamate decarboxylase from Escherichia coli
Enzyme Microb. Technol.
51
171-176
2012
Corynebacterium glutamicum, Corynebacterium glutamicum GAD
Shi, F.; Xie, Y.; Jiang, J.; Wang, N.; Li, Y.; Wang, X.
Directed evolution and mutagenesis of glutamate decarboxylase from Lactobacillus brevis Lb85 to broaden the range of its activity toward a near-neutral pH
Enzyme Microb. Technol.
61-62
35-43
2014
Levilactobacillus brevis, Levilactobacillus brevis Lb85
Yang, R.; Yin, Y.; Guo, Q.; Gu, Z.
Purification, properties and cDNA cloning of glutamate decarboxylase in germinated faba bean (Vicia faba L.)
Food Chem.
138
1945-1951
2013
Vicia faba (M1GCP8), Vicia faba
Ilg, T.; Berger, M.; Noack, S.; Rohwer, A.; Gassel, M.
Glutamate decarboxylase of the parasitic arthropods Ctenocephalides felis and Rhipicephalus microplus: gene identification, cloning, expression, assay development, identification of inhibitors by high throughput screening and comparison with the orthologs
Insect Biochem. Mol. Biol.
43
162-177
2013
Ctenocephalides felis (K7WYY0), Ctenocephalides felis, Rhipicephalus microplus (K7XPX5), Rhipicephalus microplus, Drosophila melanogaster (P20228), Drosophila melanogaster, Mus musculus (P48318), Mus musculus (P48320), Mus musculus
Park, H.; Ahn, J.; Lee, J.; Lee, H.; Kim, C.; Jung, J.K.; Lee, H.; Lee, E.G.
Expression, immobilization and enzymatic properties of glutamate decarboxylase fused to a cellulose-binding domain
Int. J. Mol. Sci.
13
358-368
2012
Escherichia coli
Kanwal, S.; Rastogi, R.; Incharoensakdi, A.
Glutamate decarboxylase activity and gamma-aminobutyric acid content in Synechocystis sp. PCC 6803 under osmotic stress and different carbon sources
J. Appl. Phycol.
26
23272333
2014
Synechocystis sp.
-
Thu Ho, N.A.; Hou, C.Y.; Kim, W.H.; Kang, T.J.
Expanding the active pH range of Escherichia coli glutamate decarboxylase by breaking the cooperativeness
J. Biosci. Bioeng.
115
154-158
2013
Escherichia coli
Jun, C.; Joo, J.C.; Lee, J.H.; Kim, Y.H.
Thermostabilization of glutamate decarboxylase B from Escherichia coli by structure-guided design of its pH-responsive N-terminal interdomain
J. Biotechnol.
174
22-28
2014
Escherichia coli (P69910), Escherichia coli
Le Vo, T.D.; Ko, J.S.; Park, S.J.; Lee, S.H.; Hong, S.H.
Efficient gamma-aminobutyric acid bioconversion by employing synthetic complex between glutamate decarboxylase and glutamate/GABA antiporter in engineered Escherichia coli
J. Ind. Microbiol. Biotechnol.
40
927-933
2013
Escherichia coli
De Biase, D.; Pennacchietti, E.
Glutamate decarboxylase-dependent acid resistance in orally acquired bacteria: function, distribution and biomedical implications of the gadBC operon
Mol. Microbiol.
86
770-786
2012
Escherichia coli, Listeria monocytogenes, Levilactobacillus brevis (A9ZM78), Levilactobacillus brevis (Q03U69), Levilactobacillus brevis ATCC 367 (Q03U69), Levilactobacillus brevis FO12005 (A9ZM78)
Lee, E.; Kim, H.; Kim, D.; Kim, Y.; Nam, S.; Kim, B.; Jeon, S.
Gene expression and characterization of thermostable glutamate decarboxylase from Pyrococcus furiosus
Biotechnol. Bioprocess Eng.
18
375-381
2013
Pyrococcus furiosus (Q8U1P6)
-
Okai, N.; Takahashi, C.; Hatada, K.; Ogino, C.; Kondo, A.
Disruption of pknG enhances production of gamma-aminobutyric acid by Corynebacterium glutamicum expressing glutamate decarboxylase
AMB Express
4
20
2014
Escherichia coli (A5YKJ2), Escherichia coli
Zhao, A.; Hu, X.; Li, Y.; Chen, C.; Wang, X.
Extracellular expression of glutamate decarboxylase B in Escherichia coli to improve gamma-aminobutyric acid production
AMB Express
6
55
2016
Escherichia coli (P69910), Escherichia coli, Escherichia coli K-12 / W3110 (P69910)
Shi, F.; Luan, M.; Li, Y.
Ribosomal binding site sequences and promoters for expressing glutamate decarboxylase and producing gamma-aminobutyrate in Corynebacterium glutamicum
AMB Express
8
61
2018
Escherichia coli (A0A0J2E2M6), Escherichia coli (A0A2Y0HLE8)
Choi, J.; Lee, S.; Linares-Pasten, J.A.; Nilsson, L.
Study on oligomerization of glutamate decarboxylase from Lactobacillus brevis using asymmetrical flow field-flow fractionation (AF4) with light scattering techniques
Anal. Bioanal. Chem.
410
451-458
2018
Levilactobacillus brevis (A0A1U9Y677), Levilactobacillus brevis, Levilactobacillus brevis DSM 1269 (A0A1U9Y677)
Xiong, Q.; Xu, Z.; Xu, L.; Yao, Z.; Li, S.; Xu, H.
Efficient production of gamma-GABA using recombinant E. coli expressing glutamate decarboxylase (GAD) derived from eukaryote Saccharomyces cerevisiae
Appl. Biochem. Biotechnol.
183
1390-1400
2017
Saccharomyces cerevisiae, Saccharomyces cerevisiae NX-1
Astegno, A.; Capitani, G.; Dominici, P.
Functional roles of the hexamer organization of plant glutamate decarboxylase
Biochim. Biophys. Acta
1854
1229-1237
2015
Arabidopsis thaliana (Q42521), Arabidopsis thaliana
Su, L.; Huang, Y.; Wu, J.
Enhanced production of recombinant Escherichia coli glutamate decarboxylase through optimization of induction strategy and addition of pyridoxine
Biores. Technol.
198
63-69
2015
Escherichia coli (P69910), Escherichia coli
Lee, J.Y.; Jeon, S.J.
Characterization and immobilization on nickel-chelated Sepharose of a glutamate decarboxylase A from Lactobacillus brevis BH2 and its application for production of GABA
Biosci. Biotechnol. Biochem.
78
1656-1661
2014
Levilactobacillus brevis (A7UMP3), Levilactobacillus brevis, Levilactobacillus brevis BH2 (A7UMP3)
Vo, T.; Pham, V.; Ko, J.; Lee, S.; Park, S.; Hong, S.
Improvement of gamma-amino butyric acid production by an overexpression of glutamate decarboxylase from Pyrococcus horikoshii in Escherichia coli
Biotechnol. Bioprocess Eng.
19
327-331
2014
Pyrococcus horikoshii
-
Liu, Q.; Cheng, H.; Ma, X.; Xu, N.; Liu, J.; Ma, Y.
Expression, characterization and mutagenesis of a novel glutamate decarboxylase from Bacillus megaterium
Biotechnol. Lett.
38
1107-1113
2016
Priestia megaterium (A0A0U3JTC9), Priestia megaterium, Priestia megaterium CICC10055 (A0A0U3JTC9)
Kariminik, A.; Saeidi, M.; Parsia, P.
Cloning and expression of rice glutamate decarboxylase (GAD) in Escherichia coli
Cell. Mol. Biol. (Noisy-le-grand)
63
106-108
2017
Oryza sativa
Tavakoli, Y.; Esmaeili, A.; Saber, H.
Increasing thermal stability and catalytic activity of glutamate decarboxylase in E. coli an in silico study
Comput. Biol. Chem.
64
74-81
2016
Escherichia coli (P69908), Escherichia coli
Grassini, G.; Pennacchietti, E.; Cappadocio, F.; Occhialini, A.; De Biase, D.
Biochemical and spectroscopic properties of Brucella microti glutamate decarboxylase, a key component of the glutamate-dependent acid resistance system
FEBS open bio
5
209-218
2015
Brucella microti (C7LHI0), Brucella microti, Brucella microti CCM 4915 (C7LHI0)
Shin, S.M.; Kim, H.; Joo, Y.; Lee, S.J.; Lee, Y.J.; Lee, S.J.; Lee, D.W.
Characterization of glutamate decarboxylase from Lactobacillus plantarum and its C-terminal function for the pH dependence of activity
J. Agric. Food Chem.
62
12186-12193
2014
Lactiplantibacillus plantarum subsp. plantarum (D7VEX3), Lactiplantibacillus plantarum subsp. plantarum ATCC 14917 / JCM 1149 / CGMCC 1.2437 (D7VEX3)
Fan, L.Q.; Li, M.W.; Qiu, Y.J.; Chen, Q.M.; Jiang, S.J.; Shang, Y.J.; Zhao, L.M.
Increasing thermal stability of glutamate decarboxylase from Escherichia coli by site-directed saturation mutagenesis and its application in GABA production
J. Biotechnol.
278
1-9
2018
Escherichia coli (A5YKJ2), Escherichia coli
Yang, S.; Lin, Q.; Lu, Z.-X.; Lu, F.-X.; Bie, X.-M.; Zou, X.-K.; Sun, L.-J.
Characterization of a novel glutamate decarboxylase from Streptococcus salivarius ssp. thermophilus Y2
J. Chem. Technol. Biotechnol.
83
855-861
2008
Streptococcus thermophilus (Q0GE18), Streptococcus thermophilus DSM 20617 (Q0GE18)
-
Dinh, T.; Ho, N.; Kang, T.; Mcdonald, K.; Won, K.
Salt-free production of gamma-aminobutyric acid from glutamate using glutamate decarboxylase separated from Escherichia coli
J. Chem. Technol. Biotechnol.
89
1432-1436
2014
Escherichia coli (P69910)
-
Dinh, T.; Jang, N.; Mcdonald, K.; Won, K.
Cross-linked aggregation of glutamate decarboxylase to extend its activity range toward alkaline pH
J. Chem. Technol. Biotechnol.
90
2100-2105
2015
Escherichia coli (P69910)
-
Chang, C.; Zhang, J.; Ma, S.; Wang, L.; Wang, D.; Zhang, J.; Gao, Q.
Purification and characterization of glutamate decarboxylase from Enterococcus raffinosus TCCC11660
J. Ind. Microbiol. Biotechnol.
44
817-824
2017
Enterococcus raffinosus, Enterococcus raffinosus TCCC11660 / CGMCC 5584
Sa, H.D.; Park, J.Y.; Jeong, S.J.; Lee, K.W.; Kim, J.H.
Characterization of glutamate decarboxylase (GAD) from Lactobacillus sakei A156 isolated from Jeot-gal
J. Microbiol. Biotechnol.
25
696-703
2015
Latilactobacillus sakei (A0A0D3R1A0), Latilactobacillus sakei, Latilactobacillus sakei A156 (A0A0D3R1A0)
Lee, K.W.; Shim, J.M.; Yao, Z.; Kim, J.A.; Kim, H.J.; Kim, J.H.
Characterization of a glutamate decarboxylase (GAD) from Enterococcus avium M5 isolated from Jeotgal, a Korean fermented seafood
J. Microbiol. Biotechnol.
27
1216-1222
2017
Enterococcus avium (E0D5D7), Enterococcus avium, Enterococcus avium M5 (E0D5D7)
Tajabadi, N.; Baradaran, A.; Ebrahimpour, A.; Rahim, R.A.; Bakar, F.A.; Manap, M.Y.; Mohammed, A.S.; Saari, N.
Overexpression and optimization of glutamate decarboxylase in Lactobacillus plantarum Taj-Apis362 for high gamma-aminobutyric acid production
Microb. Biotechnol.
8
623-632
2015
Lactiplantibacillus plantarum (W0P1N8), Lactiplantibacillus plantarum Taj-Apis362 (W0P1N8)
Choi, J.W.; Yim, S.S.; Lee, S.H.; Kang, T.J.; Park, S.J.; Jeong, K.J.
Enhanced production of gamma-aminobutyrate (GABA) in recombinant Corynebacterium glutamicum by expressing glutamate decarboxylase active in expanded pH range
Microb. Cell Fact.
14
21
2015
Escherichia coli
Chou, C.C.; Modi, J.P.; Wang, C.Y.; Hsu, P.C.; Lee, Y.H.; Huang, K.F.; Wang, A.H.; Nan, C.; Huang, X.; Prentice, H.; Wei, J.; Wu, J.Y.
Activation of brain L-glutamate decarboxylase 65 isoform (GAD65) by phosphorylation at threonine 95 (T95)
Mol. Neurobiol.
54
866-873
2017
Homo sapiens (Q05329), Homo sapiens (Q99259), Homo sapiens, Rattus norvegicus (Q05683), Rattus norvegicus Sprague Dawley (Q05683)
Hwang, I.K.; Li, H.; Yoo, K.-Y.; Choi, J.H.; Lee, C.H.; Chung, D.W.; Kim, D.W.; Seong, J.K.; Yoon, Y.S.; Lee, I.S.; Won, M.-H.
Comparison of glutamic acid decarboxylase 67 immunoreactive neurons in the hippocampal CA1 region at various age stages in dogs
Neurosci. Lett.
431
251-255
2008
Canis lupus familiaris
Awad, R.; Crump, K.; Mullally, M.; Sardana, R.K.; Arnason, J.T.; Trudeau, V.L.
An improved method for production of recombinant human glutamic acid decarboxylase 65 for use in phytopharmaceutical assessment
Pharm. Biol.
46
72-81
2008
Homo sapiens (Q05329)
-
Kanwal, S.; Incharoensakdi, A.
Characterization of glutamate decarboxylase from Synechocystis sp. PCC6803 and its role in nitrogen metabolism
Plant Physiol. Biochem.
99
59-65
2016
Synechocystis sp. PCC 6803 (P73043)
Huang, Y.; Su, L.; Wu, J.
Pyridoxine supplementation improves the activity of recombinant glutamate decarboxylase and the enzymatic production of gama-aminobutyric acid
PLoS ONE
11
e0157466
2016
Escherichia coli (P69910), Escherichia coli K-12 / MG1655 (P69910)
Giovannercole, F.; Merigoux, C.; Zamparelli, C.; Verzili, D.; Grassini, G.; Buckle, M.; Vachette, P.; De Biase, D.
On the effect of alkaline pH and cofactor availability in the conformational and oligomeric state of Escherichia coli glutamate decarboxylase
Protein Eng. Des. Sel.
30
235-244
2017
Escherichia coli (P69910), Escherichia coli
Sankar, B.; Kishore, S.; Saurav, D.; Madhumita, B.
Structural and functional analysis of glutamate decarboxylase system in Bacillus aryabhattai
Res. J. Biotechnol.
11
1-11
2016
Priestia aryabhattai, Priestia aryabhattai B8W22
-
Lim, H.S.; Seo, D.H.; Cha, I.T.; Lee, H.; Nam, Y.D.; Seo, M.J.
Expression and characterization of glutamate decarboxylase from Lactobacillus brevis HYE1 isolated from kimchi
World J. Microbiol. Biotechnol.
34
44
2018
Levilactobacillus brevis (A0A0B5CSE1), Levilactobacillus brevis, Levilactobacillus brevis HYE1 (A0A0B5CSE1)
html completed
