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Literature summary for 4.1.1.15 extracted from

  • Nishimura, K.; Kitamura, Y.; Umesono, Y.; Takeuchi, K.; Takata, K.; Taniguchi, T.; Agata, K.
    Identification of glutamic acid decarboxylase gene and distribution of GABAergic nervous system in the planarian Dugesia japonica (2008), Neuroscience, 153, 1103-1114.
    View publication on PubMed
Search for more literature for 4.1.1.15

Cloned(Commentary)

Cloned (Comment) Organism
gene DjGAD, DNA and amino acid sequence determination and analysis Dugesia japonica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamate Dugesia japonica GAD is the rate-limiting enzyme for GABA biosynthesis 4-aminobutanoate + CO2
-
 ?
L-glutamate Dugesia japonica SSP GAD is the rate-limiting enzyme for GABA biosynthesis 4-aminobutanoate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Dugesia japonica
-
-
-
Dugesia japonica SSP
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
nervous system including brain and ventral nerve cords, distribution pattern of GAD protein and mRNA, dotted expression pattern, a few cells located in both the head and pharynx regions express DjGAD mRNA, overview Dugesia japonica
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neuron DjGAD-immunopositive neurons in the anterior region, distribution pattern of GAD protein and mRNA, dotted expression pattern, a few cells located in both the head and pharynx regions express DjGAD mRNA, overview Dugesia japonica
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate
-
 Dugesia japonica 4-aminobutanoate + CO2
-
 ?
L-glutamate GAD is the rate-limiting enzyme for GABA biosynthesis Dugesia japonica 4-aminobutanoate + CO2
-
 ?
L-glutamate
-
 Dugesia japonica SSP 4-aminobutanoate + CO2
-
 ?
L-glutamate GAD is the rate-limiting enzyme for GABA biosynthesis Dugesia japonica SSP 4-aminobutanoate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
GAD
-
 Dugesia japonica
Glutamic acid decarboxylase
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 Dugesia japonica