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Literature summary for 4.1.1.15 extracted from

  • Nathan, B.; Hsu, C.C.; Bao, J.; Wu, R.; Wu, J.Y.
    Purification and characterization of a novel form of brain L-glutamate decarboxylase. A Ca2+-dependent peripheral membrane protein (1994), J. Biol. Chem., 269, 7249-7254.
    View publication on PubMed
Search for more literature for 4.1.1.15

Activating Compound

Activating Compound Comment Organism Structure
3-Mercaptopropionic acid
-
 Sus scrofa
aminooxyacetic acid
-
 Sus scrofa
PCMB
-
 Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7
-
 L-Glu
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
peripheral membrane protein
-
 Sus scrofa
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
 2 * 60000, SDS-PAGE Sus scrofa
118000
-
 nondenaturing PAGE Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Glu Sus scrofa production of 4-aminobutanoate, which is the major inhibitory neurotransmitter in the mammalian brain ?
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.462
-
-
 Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Asp 2% of the activity with L-Glu Sus scrofa ?
-
 ?
L-Cysteine sulfinic acid 8% of the activity with L-Glu Sus scrofa ?
-
 ?
L-Glu
-
 Sus scrofa 4-Aminobutanoate + CO2
-
 ?
L-Glu production of 4-aminobutanoate, which is the major inhibitory neurotransmitter in the mammalian brain Sus scrofa ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 60000, SDS-PAGE Sus scrofa

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
 45 min, 78% loss of activity Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Sus scrofa