Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of cerebellum-selective GAD67-knockout mice, selective GAD67 deletion in the cerebellum iss achieved using a Cre-loxP strategy. GABA level is reduced to 16-44% in the cerebellum but not in the cerebrum, inhibitory synaptic transmission to Purkinje cells is seriously impaired, however, the morphology of Purkinje cells and the density of synaptic terminals in the cerebellar cortex appears unaffected, phenotype, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate | Mus musculus | - |
4-aminobutanoate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
cerebellum | Purkinje cells and cerebellar cortex | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-glutamate | - |
Mus musculus | 4-aminobutanoate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GAD67 | - |
Mus musculus |
glutamate decarboxylase 67 | - |
Mus musculus |