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Literature summary for 4.1.1.15 extracted from
- Induction of oral tolerance to prevent diabetes with transgenic plants requires glutamic acid decarboxylase (GAD) and IL-4 (2004), Proc. Natl. Acad. Sci. USA, 101, 5680-5685.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | enzyme plus murine IL-4 expressed in tobacco and fed to nonobese diabetic mice protects from diabetes. Feeding enhances levels of IgG1 anti-enzyme antibodies, increases splenocyte IL-4/IFN-gamma cytokine responses and produces protective regulatory T-cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
coexpression with murine IL-4 in tobacco | - |
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Release 2023.1 (January 2023)
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