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Literature summary for 4.1.1.15 extracted from

  • Wu, J.Y.; Matsuda, T.; Roberts, E.
    Purification and characterization of glutamate decarboxylase from mouse brain (1973), J. Biol. Chem., 248, 3029-3034.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.7
-
L-Glu
-
Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
2 * 44000, high speed equilibrium sedimentation after treatment with 6 M guanidine HCl and 0.1 M beta-mercaptoethanol Mus musculus
85000
-
high speed sedimentation equilibrium Mus musculus
86000
-
gel filtration Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Asp 3-5% of the activity with L-Glu Mus musculus ?
-
?
L-Glu
-
Mus musculus 4-Aminobutanoate + CO2
-
?

Subunits

Subunits Comment Organism
dimer 2 * 44000, high speed equilibrium sedimentation after treatment with 6 M guanidine HCl and 0.1 M beta-mercaptoethanol Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Mus musculus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate Km: 0.00005 mM Mus musculus