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Literature summary for 4.1.1.15 extracted from

  • Sivertsen, T.; Nygaard, A.K.; Mathisen, G.; Fonnum, F.
    Effects of 4-methylimidazole on cerebral glutamate decarboxylase activity and specific GABA receptor binding in mice (2009), Toxicol. Mech. Methods, 19, 214-218.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.15

Inhibitors

Inhibitors Comment Organism Structure
1-Methylimidazole about 85% residual activity at 5 mM, about 77% residual activity at 10 mM, about 65% residual activity at 20 mM Mus musculus
4-methylimidazole about 75% residual activity at 5 mM, about 70% residual activity at 10 mM, about 58% residual activity at 20 mM Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamate Mus musculus
-
 4-aminobutanoate + CO2
-
 ?
L-glutamate Mus musculus B6D2
-
 4-aminobutanoate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Mus musculus B6D2
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate
-
 Mus musculus 4-aminobutanoate + CO2
-
 ?
L-glutamate
-
 Mus musculus B6D2 4-aminobutanoate + CO2
-
 ?

Synonyms

Synonyms Comment Organism
GAD
-
 Mus musculus