Reference on EC 3.5.1.4 - amidase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ciskanik, L.M.; Wilczek, J.M.; Fallon, R.D.
Purification and characterization of an enantioselective amidase from Pseudomonas chlororaphis B23
Appl. Environ. Microbiol.
61
998-1003
1995
Pseudomonas chlororaphis, Pseudomonas chlororaphis B23
Nawaz, S.M.; Khan, A.A.; Seng J.E.; Leakey, J.E.; Siitonen, P.H.; Cerniglia, C.E.
Purification and characterization of an amidase from an acrylamide-degrading Rhodococcus sp.
Appl. Environ. Microbiol.
60
3343-3348
1994
Brevibacterium sp., Pseudomonas sp., Pseudomonas aeruginosa, Rhodococcus sp.
Silman, N.J.; Carver, A.M.; Jones, C.W.
Directed evolution of amidase in Methylophilus methylotrophus; purification and properties of amidases from wild-type and mutants strains
J. Gen. Microbiol.
137
169-178
1991
Arthrobacter sp., Methylophilus methylotrophus, Pseudomonas aeruginosa
-
Mayaux, J.F.; Cerbelaud, E.; Soubrier, F.; Yeh, P.; Blanche, F.; Petre, D.
Purification, cloning and primary structure of a new enantiomer-selective amidase from a Rhodococcus Strain: structural evidence for a conserved genetic coupling with nitrile hydratase
J. Bacteriol.
173
6694-6704
1991
Brevibacterium sp., Rhodococcus sp., Brevibacterium sp. R312
Soong, C.L.; Ogawa, J.; Shimizu, S.
A novel amidase, half-amidase, for half-amide hydrolysis involved in the metabolism of cyclic imides
Appl. Environ. Microbiol.
66
1947-1952
2000
Blastobacter sp.
Sutherland, P.J.; Tobin, A.E.; Rutherford, C.L.; Price N.P.J.
Dictyostelium discoideum fatty-acyl amidase II has deacylase activity on Rhizobium nodulation factors
J. Biol. Chem.
273
4459-4464
1998
Dictyostelium discoideum
Chen, Z.; Potempa, J.; Polanowski, A.; Renvert, S.; Wikstroem, M.; Travis, J.
Stimulation of proteinase and amidase activities in Porphyromonas (Bacteroides) gingivalis by amino acids and dipeptides
Infect. Immun.
59
2846-2850
1991
Porphyromonas gingivalis, Porphyromonas gingivalis OMGS 100
Kobayashi, M.; Komeda, H.; Nagasawa, T.; Nishiyama, M.; Hoinouchi, Sueharu.; Beppu, T.; Yamada, H.; Shimizu.
Amidase couple with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1
Eur. J. Biochem.
217
327-336
1993
Escherichia coli, Rhodococcus rhodochrous, Escherichia coli JM109, Rhodococcus rhodochrous J1
Hirrlinger, B.; Stolz, A.; Knackmuss, H.J.
Purification and properties of an amidase from Rhodococcus erythropolis MP50 which enantioselectively hydrolyzes 2-arylpropionamides
J. Bacteriol.
178
3501-3507
1996
Rhodococcus erythropolis, Rhodococcus erythropolis MP50
Nawaz, M.S.; Khan, A.A.; Bhattacharayya, D.; Siitonen, P.H.; Cerniglia, C.E.
Physical, biochemical, and immunological characterization of a thermostable amidase from Klebsiella pneumoniae NCTR 1
J. Bacteriol.
178
2397-2401
1996
Klebsiella pneumoniae
Hayashi, T.; Yamamoto, K.; Matsuo, A.; Otsubo, K.; Muramatsu, S.; Matsuda, A.; Komatsu, K.I.
Characterization and cloning of an enantioselective amidase from Comamonas acidovorans KPO-2771-4
J. Ferment. Bioeng.
83
139-145
1997
Delftia acidovorans, Escherichia coli, Delftia acidovorans KPO-2771-4, Escherichia coli JM109
-
Rajagopal, R.; Tsurusaki, K.I.; Kannangara, G.; Kuraishi, S.; Sakurai, N.
Natural ccurrence of indoleacetamide and amidohydrolase activity in etiolated aseptically-grown squash seedlings
Plant Cell Physiol.
35
329-339
1994
Agrobacterium tumefaciens, Cucurbita maxima
-
Brown, P.R.; Smyth, M.J.; Clarke, P.H.; Rosemeyer, M.A.
The subunit structure of the aliphatic amidase from Pseudomonas aeruginosa
Eur. J. Biochem.
34
177-187
1973
Pseudomonas aeruginosa, Pseudomonas aeruginosa PAC 142 (L10R), Pseudomonas aeruginosa PAC 111 (C11)
Woods, M.J.; Orsi, B.A.
Selective inhibition and the kinetic mechanism of the aliphatic amidase of Pseudomonas aeruginosa
Biochem. Soc. Trans.
552
1344-1345
1974
Pseudomonas aeruginosa
-
Alt, J.; Krisch, K.
Isolation of an inducible amidase from Pseudomonas acidovorans AE1
J. Gen. Microbiol.
87
260-272
1975
Delftia acidovorans, Delftia acidovorans AE1
Alt, J.; Heymann, E.; Krisch, K.
Characterization of an inducible amidase from Pseudomonas acidovorans AE1
Eur. J. Biochem.
53
357-369
1975
Delftia acidovorans, Delftia acidovorans AE1
Woods, M.J.; Findlater, J.D.; Orsi, B.A.
Kinetic mechanismen of the aliphatic amidase from Pseudomonas aeruginosa
Biochim. Biophys. Acta
567
225-237
1979
Pseudomonas aeruginosa
Gregoriou, M.; Brown, P.R.
Inhibition of the aliphatic amidase from Pseudomonas aeruginosa by urea and related compounds
Eur. J. Biochem.
96
101-108
1979
Pseudomonas aeruginosa, Pseudomonas aeruginosa AI3
Maestracci, M.; Bui, K.; Thiery, A.; Arnaud, A.; Galzy, P.
A study of the inhibition of an amidase with a wide substrate spectrum and its consequences for the bioconversation of nitriles
Biotechnol. Lett.
6
149-154
1984
Brevibacterium sp.
-
Maestracci, M.; Thiery, A.; Bui, K.; Arnaud, A.; Galzy, P.
Activity and regulation of an amidase, acylamide amidohydrolase EC 3.5.1.4, with a wide substrate spectrum from a Brevibacterium sp.
Arch. Microbiol.
138
315-320
1984
Brevibacterium sp., Brevibacterium sp. R312
-
Maestracci, M.; Thiery, A.; Arnaud, A.; Galzy, P.
A study of the mechanism of the reactions catalyzed by the amidase Brevibacterium sp. R312
Agric. Biol. Chem.
50
2237-2241
1986
Brevibacterium sp., Brevibacterium sp. R312
-
Wyndham, R.C.; Slater, J.H.
A comparative study of acquired amidase activity in Pseudomaonas species
J. Gen. Microbiol.
132
2185-2204
1986
Pseudomonas aeruginosa, Pseudomonas putida, Pseudomonas putida PP3
-
Thiery, A.; Maestracci, M.; Arnaud, A.; Galzy, P.
Acyltransferase activity of the wide spectrum amidase of Brevibacterium sp. R312
J. Gen. Microbiol.
132
2205-2208
1986
Brevibacterium sp.
-
Ambler, R.P.; Auffret, A.D.; Clarke, P.H.
The amino acid sequence of the aliphatic amidase from Pseudomonas aeruginosa
FEBS Lett.
215
285-290
1987
Pseudomonas aeruginosa, Pseudomonas aeruginosa PAC 142 (L10R)
Garcia, J.L.; Garcia, E.; Lopez, R.
Overproduction and rapid purification of the amidase of Streptococcus pneumoniae
Arch. Microbiol.
149
52-56
1987
Streptococcus pneumoniae, Escherichia coli, Escherichia coli RB791
Farnaud, S.; Tata, Renee.; Sohi, M.K.; Wan, P.R.; Sutton, B.J.
Evidence that cysteine-166 is the active-site nucleophile of Pseudomonas aeruginasa amidase: crystallization and preliminary X-ray diffraction analysis of the enzyme
Biochem. J.
340
711-714
1999
Escherichia coli, Pseudomonas aeruginosa, Escherichia coli JM109
Kobayashi, M.; Fujiwara, Y.; Goda, M.; Komeda, H.; Shimizu, S.
Identification of active sites in amidase: Evolutionary relationship between amide bond- and peptide bond-cleaving enzymes
Proc. Natl. Acad. Sci. USA
94
11987-11991
1997
Escherichia coli, Rhodococcus rhodochrous, Escherichia coli JM109, Rhodococcus rhodochrous J1
Skouloubris, S.; Labigne, A.; de Reuse H.
Identification and characterization of an aliphatic amidase in Helicobacter pylori
Mol. Microbiol.
25
989-998
1997
Helicobacter pylori
Nastopoulos, V.; Vallone, B.; Politi, L.; Scotto d'Abusco, A.; Scandurra, R.; Tsernoglou, D.
Crystallization and X-ray diffraction measurements of a thermophilic archaeal recombinant amidase from Sulfolobus solfataricus MT4
Acta Crystallogr. Sect. D
D57
1036-1037
2001
Saccharolobus solfataricus, Saccharolobus solfataricus MT4
Pacheco, R.; Serralheiro, M.L.M.; Karmali, A.; Haris, P.I.
Measuring enzymatic activity of a recombinant amidase using Fourier transform infrared spectroscopy
Anal. Biochem.
322
208-214
2003
Pseudomonas aeruginosa, Pseudomonas aeruginosa 8602
Novo, C.; Farnaud, S.; Tata, R.; Clemente, A.; Brown, P.R.
Support for a three-dimensional structure predicting a Cys-Glu-Lys catalytic triad for Pseudomonas aeruginosa amidase comes from site-directed mutagenesis and mutations altering substrate specificity
Biochem. J.
365
731-738
2002
Pseudomonas aeruginosa (P11436), Pseudomonas aeruginosa
Cerovsky, V.; Kula, M.R.
Studies on peptide amidase-catalyzed C-terminal peptide amidation in organic media with respect to its substrate specificity
Biotechnol. Appl. Biochem.
33
183-187
2001
Citrus sinensis
Holt, S.; Nilsson, J.; Omeir, R.; Tiger, G.; Fowler, C.J.
Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen
Br. J. Pharmacol.
133
513-520
2001
Rattus norvegicus
Fournand, D.; Arnaud, A.
Aliphatic and enantioselective amidases: from hydrolysis to acyl transfer activity
J. Appl. Microbiol.
91
381-393
2001
Cyberlindnera jadinii, Mycobacterium avium, Rhodococcus sp., Sus scrofa, Torula cremoris, Rhodococcus sp. R312
Uehara, T.; Park, J.T.
Identification of MpaA, an amidase in Escherichia coli that hydrolyzes the gamma-D-glutamyl-meso-diaminopimelate bond in murein peptides
J. Bacteriol.
185
679-682
2003
Escherichia coli
Hildmann, C.; Ninkovic, M.; Dietrich, R.; Wegener, D.; Riester, D.; Zimmermann, T.; Birch, O.M.; Bernegger, C.; Loidl, P.; Schwienhorst, A.
A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases
J. Bacteriol.
186
2328-2339
2004
Alcaligenes sp. (Q70I53), Alcaligenes sp. DSM 11172 (Q70I53)
Saiz, J.L.; Lopez-Zumel, C.; Monterroso, B.; Varea, J.; Arrondo, J.L.R.; Iloro, I.; Garcia, J.L.; Laynez, J.; Menendez, M.
Characterization of Ej1, the cell-wall amidase coded by the pneumococcal bacteriophage Ej-1
Protein Sci.
11
1788-1799
2002
Streptococcus phage EJ-1
Robins, K.
Biotechnologisches Verfahren zur Herstellung von (S)-(+)-2,2-Dimethylcyclopropancarboxamid und (R)-(-)-2,2-Dimethylcyclopropancarbonsure
Lonza AG
EP
0502525 A1
1993
Delftia acidovorans
-
Eichhorn, E.; Roduit, J.P.; Shaw, N.; Heinzmann, K.; Kiener, A.
Preparation of (S)-piperazine-2-carboxylic acid, (R)-piperazine-2-carboxylic acid, and (S)-pipecolic acid by kinetic resolution of the corresponding racemic carboxamides with stereoselective amidase in whole bacterial cells
Tetrahedron Asymmetry
8
2533-2536
1997
Raoultella terrigena
-
Kohyama, E.; Yoshimura, A.; Aoshima, D.; Yoshida, T.; Kawamoto, H.; Nagasawa, T.
Convenient treatment of acetonitrile-containing wastes using the tandem combination of nitrile hydratase and amidase-producing microorganisms
Appl. Microbiol. Biotechnol.
72
600-606
2006
Brevundimonas diminuta, Brevundimonas diminuta AM10-C-1
Vandevoorde, S.; Saha, B.; Mahadevan, A.; Razdan, R.K.; Pertwee, R.G.; Martin, B.R.; Fowler, C.J.
Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase
Biochem. Biophys. Res. Commun.
337
104-109
2005
Rattus norvegicus
Hollaway, M.R.; Clarke, P.H.; Ticho, T.
Chloroacetone as an active-site-directed inhibitor of the aliphatic amidase from Pseudomonas aeruginosa
Biochem. J.
191
811-826
1980
Pseudomonas aeruginosa, Pseudomonas aeruginosa PAC142
Domingos, A.; Karmali, A.; Brown, P.R.
One-step affinity purification of amidase from mutant strains of Pseudomonas aeruginosa
Biochimie
71
1179-1184
1989
Pseudomonas aeruginosa
Reisinger, C.; Osprian, I.; Glieder, A.; Schoemaker, H.E.; Griengl, H.; Schwab, H.
Enzymatic hydrolysis of cyanohydrins with recombinant nitrile hydratase and amidase from Rhodococcus erythropolis
Biotechnol. Lett.
26
1675-1680
2004
Rhodococcus erythropolis (P22984), Rhodococcus erythropolis, Rhodococcus erythropolis NCIMB11540 (P22984)
Ghafouri, N.; Tiger, G.; Razdan, R.K.; Mahadevan, A.; Pertwee, R.G.; Martin, B.R.; Fowler, C.J.
Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol
Br. J. Pharmacol.
143
774-784
2004
Rattus norvegicus
Vandevoorde, S.; Fowler, C.J.
Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate
Br. J. Pharmacol.
145
885-893
2005
Rattus norvegicus
Novo, C.; Tata, R.; Clemente, A.; Brown, P.R.
Burkholderia genome analysis reveals new enzymes belonging to the nitrilase superfamily. The amidase of Burkholderia cepacia (hospital isolate)
Int. J. Biol. Macromol.
33
175-182
2003
Burkholderia cepacia, Burkholderia cepacia C
Kashiwagi, M.; Fuhshuku, K.I.; Sugai, T.
Control of the nitrile-hydrolyzing enzyme activity in Rhodococcus rhodochrous IFO 15564: preferential action of nitrile hydratase and amidase depending on the reaction condition factors and its application to the one-pot preparation of amides from aldehydes
J. Mol. Catal. B
29
249-258
2004
Rhodococcus rhodochrous, Rhodococcus rhodochrous IFO 15564
-
Karmali, A.; Pacheco, R.; Tata, R.; Brown, P.
Substitutions of Thr-103-Ile and Trp-138-Gly in amidase from Pseudomonas aeruginosa are responsible for altered kinetic properties and enzyme instability
Mol. Biotechnol.
17
201-212
2001
Pseudomonas aeruginosa
Egorova, K.; Trauthwein, H.; Verseck, S.; Antranikian, G.
Purification and properties of an enantioselective and thermoactive amidase from the thermophilic actinomycete Pseudonocardia thermophila
Appl. Microbiol. Biotechnol.
65
38-45
2004
Pseudonocardia thermophila
Benedetti, F.; Berti, F.; Brady, K.; Colombatti, A.; Pauletto, A.; Pucillo, C.; Thomas, N.R.
An unprecedented catalytic motif revealed in the model structure of amide hydrolyzing antibody 312D6
Chembiochem
5
129-131
2004
Human immunodeficiency virus 1
Cai, G.; Zhu, S.; Wang, X.; Jiang, W.
Cloning, sequence analysis and expression of the gene encoding a novel wide-spectrum amidase belonging to the amidase signature superfamily from Achromobacter xylosoxidans
FEMS Microbiol. Lett.
249
15-21
2005
Achromobacter xylosoxidans (Q5YFS2), Achromobacter xylosoxidans
De Sousa, M.O.; Santoro, M.M.; De Souza Figueiredo, A.F.
The effect of cations on the amidase activity of human tissue kallikrein: 1-linear competitive inhibition by sodium, potassium, calcium and magnesium. 2-linear mixed inhibition by aluminium
J. Enzyme Inhib. Med. Chem.
19
317-325
2004
Homo sapiens
Suzuki, Y.; Ohta, H.
Identification of a thermostable and enantioselective amidase from the thermoacidophilic archaeon Sulfolobus tokodaii strain 7
Protein Expr. Purif.
45
368-373
2006
Sulfurisphaera tokodaii, Sulfurisphaera tokodaii 7
Shaw, N.M.; Naughton, A.B.
The substrate specificity of the heat-stable stereospecific amidase from Klebsiella oxytoca
Tetrahedron
60
747-752
2004
Klebsiella oxytoca
-
Kohyama, E.; Dohi, M.; Yoshimura, A.; Yoshida, T.; Nagasawa, T.
Remaining acetamide in acetonitrile degradation using nitrile hydratase- and amidase-producing microorganisms
Appl. Microbiol. Biotechnol.
74
829-835
2007
Rhodococcus sp., Rhodococcus sp. S13-4
Andrade, J.; Karmali, A.; Carrondo, M.A.; Frazao, C.
Crystallization, diffraction data collection and preliminary crystallographic analysis of hexagonal crystals of Pseudomonas aeruginosa amidase
Acta Crystallogr. Sect. F
63
214-216
2007
Pseudomonas aeruginosa
Wu, S.; Fallon, R.D.; Payne, M.S.
Cloning and nucleotide sequence of amidase gene from Pseudomonas putida
DNA Cell Biol.
17
915-920
1998
Pseudomonas putida, Pseudomonas putida 5B
Andrade, J.; Karmali, A.; Carrondo, M.A.; Frazao, C.
Structure of amidase from Pseudomonas aeruginosa showing a trapped acyl transfer reaction intermediate state
J. Biol. Chem.
282
19598-19605
2007
Pseudomonas aeruginosa
Cisneros, J.A.; Vandevoorde, S.; Ortega-Gutierrez, S.; Paris, C.; Fowler, C.J.; Lopez-Rodriguez, M.L.
Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis - comparison with effects upon fatty acid amide hydrolase
J. Med. Chem.
50
5012-5023
2007
Rattus norvegicus
Martins, S.; Karmali, A.; Andrade, J.; Custodio, A.; Serralheiro, M.L.
Characterization of monoclonal antibodies against altered (T103I) amidase from Pseudomonas aeruginosa
Mol. Biotechnol.
30
207-219
2005
Pseudomonas aeruginosa
Martins, S.; Lourenco, S.; Karmali, A.; Serralheiro, M.L.
Monoclonal antibodies recognize conformational epitopes on wild-type and recombinant mutant amidases from Pseudomonas aeruginosa
Mol. Biotechnol.
37
136-145
2007
Pseudomonas aeruginosa, Pseudomonas aeruginosa 8602
Kimani, S.W.; Agarkar, V.B.; Cowan, D.A.; Sayed, M.F.; Sewell, B.T.
Structure of an aliphatic amidase from Geobacillus pallidus RAPc8
Acta Crystallogr. Sect. D
63
1048-1058
2007
Aeribacillus pallidus, Aeribacillus pallidus RAPc8
Agarkar, V.B.; Kimani, S.W.; Cowan, D.A.; Sayed, M.F.; Sewell, B.T.
The quaternary structure of the amidase from Geobacillus pallidus RAPc8 is revealed by its crystal packing
Acta Crystallogr. Sect. F
F62
1174-1178
2006
Aeribacillus pallidus, Aeribacillus pallidus RAPc8
Zheng, R.C.; Zheng, Y.G.; Shen, Y.C.
A screening system for active and enantioselective amidase based on its acyl transfer activity
Appl. Microbiol. Biotechnol.
74
256-262
2007
Pseudomonas sp., Rhodococcus sp., Delftia tsuruhatensis, Ochrobactrum sp., Ochrobactrum sp. T12, Delftia tsuruhatensis MA52, Rhodococcus sp. AA21, Pseudomonas sp. W13
Makhongela, H.S.; Glowacka, A.E.; Agarkar, V.B.; Sewell, B.T.; Weber, B.; Cameron, R.A.; Cowan, D.A.; Burton, S.G.
A novel thermostable nitrilase superfamily amidase from Geobacillus pallidus showing acyl transfer activity
Appl. Microbiol. Biotechnol.
75
801-811
2007
Aeribacillus pallidus, Aeribacillus pallidus RAPc8
Sit, S.Y.; Conway, C.; Bertekap, R.; Xie, K.; Bourin, C.; Burris, K.; Deng, H.
Novel inhibitors of fatty acid amide hydrolase
Bioorg. Med. Chem. Lett.
17
3287-3291
2007
Homo sapiens, Rattus norvegicus
Metaferia, B.B.; Ray, S.; Smith, J.A.; Bewley, C.A.
Design and synthesis of substrate-mimic inhibitors of mycothiol-S-conjugate amidase from Mycobacterium tuberculosis
Bioorg. Med. Chem. Lett.
17
444-447
2007
Mycobacterium tuberculosis
Timmons, A.; Seierstad, M.; Apodaca, R.; Epperson, M.; Pippel, D.; Brown, S.; Chang, L.; Scott, B.; Webb, M.; Chaplan, S.R.; Breitenbucher, J.G.
Novel ketooxazole based inhibitors of fatty acid amide hydrolase (FAAH)
Bioorg. Med. Chem. Lett.
18
2109-2113
2008
Homo sapiens
Tsuboi, K.; Takezaki, N.; Ueda, N.
The N-acylethanolamine-hydrolyzing acid amidase (NAAA)
Chem. Biodivers.
4
1914-1925
2007
Homo sapiens (O00519), Homo sapiens (Q02083), Homo sapiens, Mus musculus (O08914), Mus musculus (Q9D7V9), Mus musculus, Rattus norvegicus (P97612), Rattus norvegicus (Q5KTC7), Sus scrofa (Q9TUI8)
Lodola, A.; Mor, M.; Rivara, S.; Christov, C.; Tarzia, G.; Piomelli, D.; Mulholland, A.J.
Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling
Chem. Commun. (Camb. )
2
214-216
2008
Rattus norvegicus
Cantarella, M.; Cantarella, L.; Gallifuoco, A.; Intellini, R.; Kaplan, O.; Spera, A.; Martinkova, L.
Amidase-catalyzed production of nicotinic acid in batch and continuous stirred membrane reactors
Enzyme Microb. Technol.
42
222-229
2008
Microbacterium imperiale, Microbacterium imperiale CBS 498-74
-
Neu, D.; Lehmann, T.; Elleuche, S.; Pollmann, S.
Arabidopsis amidase 1, a member of the amidase signature family
FEBS J.
274
3440-3451
2007
Arabidopsis thaliana
Jin, S.J.; Zheng, R.C.; Zheng, Y.G.; Shen, Y.C.
R-enantioselective hydrolysis of 2,2-dimethylcyclopropanecarboxamide by amidase from a newly isolated strain Brevibacterium epidermidis ZJB-07021
J. Appl. Microbiol.
105
1150-1157
2008
Brevibacterium epidermidis, Brevibacterium epidermidis ZJB-07021
Wei, B.Q.; Mikkelsen, T.S.; McKinney, M.K.; Lander, E.S.; Cravatt, B.F.
A second fatty acid amide hydrolase with variable distribution among placental mammals
J. Biol. Chem.
281
36569-36578
2006
Homo sapiens (O00519), Homo sapiens (Q6GMR7), Homo sapiens
Kaczocha, M.; Hermann, A.; Glaser, S.T.; Bojesen, I.N.; Deutsch, D.G.
Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase
J. Biol. Chem.
281
9066-9075
2006
Rattus norvegicus
Hardouin, C.; Kelso, M.J.; Romero, F.A.; Rayl, T.J.; Leung, D.; Hwang, I.; Cravatt, B.F.; Boger, D.L.
Structure-activity relationships of alpha-ketooxazole inhibitors of fatty acid amide hydrolase
J. Med. Chem.
50
3359-3368
2007
Homo sapiens, Rattus norvegicus
Kimball, F.S.; Romero, F.A.; Ezzili, C.; Garfunkle, J.; Rayl, T.J.; Hochstatter, D.G.; Hwang, I.; Boger, D.L.
Optimization of alpha-ketooxazole inhibitors of fatty acid amide hydrolase
J. Med. Chem.
51
937-947
2008
Homo sapiens, Rattus norvegicus
Martins, S.; Andrade, J.; Karmali, A.; Serralheiro, M.L.
Screening of suitable immobilized metal chelates for adsorption of monoclonal antibodies against mutant amidase from Pseudomonas aeruginosa
J. Mol. Recognit.
19
340-347
2006
Pseudomonas aeruginosa
Massi, P.; Valenti, M.; Vaccani, A.; Gasperi, V.; Perletti, G.; Marras, E.; Fezza, F.; Maccarrone, M.; Parolaro, D.
5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid
J. Neurochem.
104
1091-1100
2008
Homo sapiens
Vinod, K.Y.; Sanguino, E.; Yalamanchili, R.; Manzanares, J.; Hungund, B.L.
Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol
J. Neurochem.
104
233-243
2008
Mus musculus
Pollmann, S.; Neu, D.; Lehmann, T.; Berkowitz, O.; Schaefer, T.; Weiler, E.W.
Subcellular localization and tissue specific expression of amidase 1 from Arabidopsis thaliana
Planta
224
1241-1253
2006
Arabidopsis thaliana
Wang, Y.S.; Shrestha, R.; Kilaru, A.; Wiant, W.; Venables, B.J.; Chapman, K.D.; Blancaflor, E.B.
Manipulation of Arabidopsis fatty acid amide hydrolase expression modifies plant growth and sensitivity to N-acylethanolamines
Proc. Natl. Acad. Sci. USA
103
12197-12202
2006
Arabidopsis thaliana
Kotlowska, M.; Dietrich, G.; Wojtczak, M.; Karol, H.; Ciereszko, A.
Effects of liquid storage on amidase activity, DNA fragmentation and motility of turkey spermatozoa
Theriogenology
67
276-286
2007
Meleagris gallopavo
Di Marzo, V.; Maccarrone, M.
FAAH and anandamide: is 2-AG really the odd one out?
Trends Pharmacol. Sci.
29
229-233
2008
Rattus norvegicus
Giordano, C.; Ammendola, S.
Characterization of mutants of Sulfolobus solfataricus signature amidase able to hydrolyse R-ketoprofen amide
Protein Pept. Lett.
15
617-623
2008
Saccharolobus solfataricus
Vaidya, B.K.; Mutalik, S.R.; Joshi, R.M.; Nene, S.N.; Kulkarni, B.D.
Enhanced production of amidase from Rhodococcus erythropolis MTCC 1526 by medium optimisation using a statistical experimental design
J. Ind. Microbiol. Biotechnol.
36
671-678
2009
Rhodococcus erythropolis
Park, H.J.; Uhm, K.N.; Kim, H.K.
R-stereoselective amidase from Rhodococcus erythropolis No. 7 acting on 4-chloro-3-hydroxybutyramide
J. Microbiol. Biotechnol.
18
552-559
2008
Rhodococcus erythropolis (B4XEY3), Rhodococcus erythropolis, Rhodococcus erythropolis No. 7 (B4XEY3)
Han, W.W.; Wang, Y.; Zhou, Y.H.; Yao, Y.; Li, Z.S.; Feng, Y.
Understanding structural/functional properties of amidase from Rhodococcus erythropolis by computational approaches
J. Mol. Model.
15
481-487
2009
Rhodococcus erythropolis (P22984), Rhodococcus erythropolis
Politi, L.; Chiancone, E.; Giangiacomo, L.; Cervoni, L.; Scotto dAbusco, A.; Scorsino, S.; Scandurra, R.
pH-, temperature- and ion-dependent oligomerization of Sulfolobus solfataricus recombinant amidase: a study with site-specific mutants
Archaea
2
221-231
2009
Saccharolobus solfataricus
Ohtaki, A.; Murata, K.; Sato, Y.; Noguchi, K.; Miyatake, H.; Dohmae, N.; Yamada, K.; Yohda, M.; Odaka, M.
Structure and characterization of amidase from Rhodococcus sp. N-771: Insight into the molecular mechanism of substrate recognition
Biochim. Biophys. Acta
1804
184-192
2010
Rhodococcus sp. N-771 (Q7DKE4)
Park, H.J.; Uhm, K.N.; Kim, H.K.
Biotransformation of amides to acids using a co-cross-linked enzyme aggregate of Rhodococcus erythropolis amidase
J. Microbiol. Biotechnol.
20
325-331
2010
Rhodococcus erythropolis
Yue, Y.; Lian, J.; Tian, P.; Tan, T.
Cloning of amidase gene from Rhodococcus erythropolis and expression by distinct promoters in Bacillus subtilis
J. Mol. Catal. B
56
89-95
2009
Rhodococcus erythropolis
-
Syed, M.; Ahmad, S.; Kusnin, N.; Shukor, M.
Purification and characterization of amidase from acrylamide-degrading bacterium Burkholderia sp. strain DR.Y27
Afr. J. Biotechnol.
11
329-336
2012
Burkholderia sp., Burkholderia sp. DR.Y27
-
Nel, A.J.; Tuffin, I.M.; Sewell, B.T.; Cowan, D.A.
Unique aliphatic amidase from a psychrotrophic and haloalkaliphilic Nesterenkonia isolate
Appl. Environ. Microbiol.
77
3696-3702
2011
Nesterenkonia sp. (C6K3Z5), Nesterenkonia sp. AN1 (C6K3Z5)
Shen, W.; Chen, H.; Jia, K.; Ni, J.; Yan, X.; Li, S.
Cloning and characterization of a novel amidase from Paracoccus sp. M-1, showing aryl acylamidase and acyl transferase activities
Appl. Microbiol. Biotechnol.
94
1007-1018
2012
Paracoccus sp. (G9FKH7)
Borges, P.; Pacheco, R.; Karmali, A.
Pseudomonas aeruginosa amidase: aggregation in recombinant Escherichia coli
Biotechnol. J.
6
888-897
2011
Pseudomonas aeruginosa, Pseudomonas aeruginosa 8602
dAbusco, A.S.; Ammendola, S.; Scandurra, R.; Politi, L.
Molecular and biochemical characterization of the recombinant amidase from hyperthermophilic archaeon Sulfolobus solfataricus
Extremophiles
5
183-192
2001
Saccharolobus solfataricus (P95896), Saccharolobus solfataricus, Saccharolobus solfataricus MT4 (P95896)
Duranti, A.; Tontini, A.; Antonietti, F.; Vacondio, F.; Fioni, A.; Silva, C.; Lodola, A.; Rivara, S.; Solorzano, C.; Piomelli, D.; Tarzia, G.; Mor, M.
N-(2-Oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships
J. Med. Chem.
55
4824-4836
2012
Rattus norvegicus
D'Abusco, A.S.; Casadio, R.; Tasco, G.; Giangiacomo, L.; Giartosio, A.; Calamia, V.; Di Marco, S.; Chiaraluce, R.; Consalvi, V.; Scandurra, R.; Politi, L.
Oligomerization of Sulfolobus solfataricus signature amidase is promoted by acidic pH and high temperature
Archaea
1
411-423
2005
Saccharolobus solfataricus (P95896), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (P95896)
Fu, L.; Li, X.; Xiao, X.; Xu, J.
Purification and characterization of a thermostable aliphatic amidase from the hyperthermophilic archaeon Pyrococcus yayanosii CH1
Extremophiles
18
429-440
2014
Pyrococcus yayanosii (F8AEP0), Pyrococcus yayanosii CH1 (F8AEP0), Pyrococcus yayanosii CH1
Cilia, E.; Fabbri, A.; Uriani, M.; Scialdone, G.G., Ammendola, S.
The signature amidase from Sulfolobus solfataricus belongs to the CX3C subgroup of enzymes cleaving both amides and nitriles. Ser195 and Cys145 are predicted to be the active site nucleophiles
FEBS J.
272
4716-4724
2005
Saccharolobus solfataricus (P95896), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (P95896)
Sharma, M.; Sharma, N.N.; Bhalla, T.C.
Purification studies on a thermo-active amidase of Geobacillus pallidus BTP-5x MTCC 9225 isolated from thermal springs of Tatapani (Himachal Pradesh)
Appl. Biochem. Biotechnol.
169
1-14
2013
Aeribacillus pallidus, Aeribacillus pallidus BTP-5x MTCC 9225
Ma, Y.; Xu, W.; Zhang, J.; Zhang, S.; Hong, K.; Deng, Z.; Sun, Y.
Nitrilase superfamily aryl acylamidase from the halotolerant mangrove Streptomyces sp. 211726
Appl. Microbiol. Biotechnol.
98
8583-8590
2014
Streptomyces sp. (A0A088BHP3), Streptomyces sp. 211726 (A0A088BHP3)
Yamano, Y.; Tsuboi, K.; Hozaki, Y.; Takahashi, K.; Jin, X.H.; Ueda, N.; Wada, A.
Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase
Bioorg. Med. Chem.
20
3658-3665
2012
Rattus norvegicus
Bhatia, R.; Bhatia, S.; Kumar, V.; Bhalla, T.
Bi-substrate kinetic analysis of acyl transfer activity of purified amidase from Pseudomonas putida BR-1
Catal. Lett.
145
1033-1040
2015
Pseudomonas putida, Pseudomonas putida BR-1
-
Mehta, P.; Bhatia, S.; Bhatia, R.; Bhalla, T.
Purification and characterization of a novel thermo-active amidase from Geobacillus subterraneus RL-2a
Extremophiles
17
637-648
2013
Geobacillus subterraneus, Geobacillus subterraneus RL-2a
Kant, B.; Kant, B.; Kumar, M.; Chand, B.
Production and characterization of acyl transfer activity of amidase from Alcaligenes sp. MTCC 10674 for synthesis of hydroxamic acids
J. Microb. Biochem. Technol.
5
1-5
2013
Alcaligenes sp., Alcaligenes sp. MTCC 10674
-
Wang, J.; Zhu, Y.; Zhao, G.; Zhu, J.; Wu, S.
Characterization of a recombinant (+)-gamma-lactamase from Microbacterium hydrocarbonoxydans which provides evidence that two enantiocomplementary gamma-lactamases are in the strain
Appl. Microbiol. Biotechnol.
99
3069-3080
2015
Microbacterium hydrocarbonoxydans (A0A077AY47), Microbacterium hydrocarbonoxydans (E3SVS0)
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