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Literature summary for 3.5.1.4 extracted from

  • Robins, K.
    Biotechnologisches Verfahren zur Herstellung von (S)-(+)-2,2-Dimethylcyclopropancarboxamid und (R)-(-)-2,2-Dimethylcyclopropancarbonsure (1993), Lonza AG, EP, 0502525 A1.
No PubMed abstract available

Application

Application Comment Organism
synthesis production of (R)-2,2-dimethylcyclopropanecarboxylic acid, which is an intermediate for the synthesis of the dehydropeptidase-inhibitor cilastatin Delftia acidovorans

Organism

Organism UniProt Comment Textmining
Delftia acidovorans
-
DSM 6351
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R/S)-2,2-dimethylcyclopropanecarboxamide + H2O
-
Delftia acidovorans (R)-2,2-dimethylcyclopropanecarboxylic acid + (S)-2,2-dimethylcyclopropanecarboxyamide
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
Delftia acidovorans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Delftia acidovorans