3.6.5.1: heterotrimeric G-protein GTPase

This is an abbreviated version!
For detailed information about heterotrimeric G-protein GTPase, go to the full flat file.

Reaction

Synonyms

cone transducin, EC 3.6.1.46, EF-2, EF-G, elongation factor 2, G alpha i2, G alpha q, G alpha11, G alphaQ, G betagamma, G12, G13, Galpha protein, Galpha-subunit, Galpha16, Galphai1, Galphai3, Galphao, Galphaq, GI, GmGalpha protein, GPA1, Gq, Gs alpha, GTP phosphohydrolase, GTPase, guanosine 5'-triphosphatase, guanosine triphosphatase, heterotrimeric G protein, heterotrimeric G protein alpha subunit, heterotrimeric G protein family, heterotrimeric G protein Gsalpha, heterotrimeric G-protein, heterotrimeric G-protein GTPase, heterotrimeric GTPase, phosphatase, guanosine tri-, photoreceptor-specific G protein, Rab1, Rab1 GTPase, Rab1a, ribosomal GTPase, SsEF-2, transducin, transducin GTPase

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.5 Acting on GTP to facilitate cellular and subcellular movement

                3.6.5.1 heterotrimeric G-protein GTPase

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Results	in table
98	Activating Compound
110	AA Sequence
3	Application
1	CAS Registry Number
16	Cloned(Commentary)
4	Crystallization (Commentary)
7114	Disease/ Diagnostics
40	General Information
19	Inhibitors
3	Ki Value [mM]
17	KM Value [mM]
27	Localization
9	Metals/Ions
18	Molecular Weight [Da]
44	Natural Substrates/ Products (Substrates)
114	Organism
22	PDB ID
12	pH Optimum
10	Posttranslational Modification
52	Protein Variants
8	Purification (Commentary)
4	Reaction
24	Reaction Type
89	Reference
97	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
77	Substrates and Products (Substrate)
39	Subunits
112	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
24	Turnover Number [1/s]

Organism

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of the Enzyme Summary Page.

Organism on EC 3.6.5.1 - heterotrimeric G-protein GTPase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Arabidopsis thaliana

-

656213, 691475, 734985, 758080

-

-

brenda

Arabidopsis thaliana Col-0

-

734985

-

-

brenda

Aspergillus nidulans

Aspergillus Emericella nidulans

674043

-

-

brenda

Bos taurus

10 entries

Caenorhabditis elegans

-

674043, 719765

-

-

brenda

Canis lupus familiaris

-

644099

-

-

brenda

Capsicum annuum

cv. California wonder

734980

-

-

brenda

Drosophila melanogaster

-

719765, 733026

-

-

brenda

Gallus gallus

-

644099

-

-

brenda

Glycine max

3 entries

Homo sapiens

4 entries

Lithobates catesbeianus

alpha subunit of transducin

644096

-

-

brenda

Lithobates grylio

alpha subunit of transducin

644096

-

-

brenda

Mammalia

-

644102, 644110, 671822, 676767

-

-

brenda

Mus musculus

-

674078, 674511, 675987, 688828, 697230, 700481, 701012

-

-

brenda

Neurospora crassa

genes gna 1-3 encoding the three subunits of the enzyme

733752

Q05425; Q05424; Q9HFW7

UniProt

brenda

Neurospora crassa 74 A-OR23-1A

genes gna 1-3 encoding the three subunits of the enzyme

733752

Q05425; Q05424; Q9HFW7

UniProt

brenda

no activity in Plasmodium falciparum

-

758125

-

-

brenda

Oryctolagus cuniculus

Gsalpha

644095

-

-

brenda

Oryza sativa

recombinant protein expressed in Escherichia coli

655939

-

-

brenda

Pasteurella multocida

-

719459

-

-

brenda

Rattus norvegicus

4 entries

Rattus norvegicus Gialpha1

Gialpha1

644109

-

-

brenda

Saccharolobus solfataricus

-

679626, 680595

-

-

brenda

Saccharomyces cerevisiae

-

674043

-

-

brenda

Saccharomyces pombe

-

697227

-

-

brenda

Secale cereale

cv. King

734985

-

-

brenda

Spodoptera frugiperda

recombinant protein expressed in baculovirus/Sf9 system, reconstituted in vesicles

656113

-

-

brenda

Sus scrofa

Gi: the G protein that mediates inhibition of adenylate cyclase

644092

-

-

brenda

Trichomonas vaginalis

-

719549

-

-

brenda

vertebrata

GTPase that functions as a component of the rhodopsin-linked, light-activated phosphodiesterase system

644094

-

-

brenda

Xenopus tropicalis

-

757559

-

-

brenda

Bos taurus

-

644101, 644111, 672055, 674078

-

-

brenda

Bos taurus

-

685385

P04896

UniProt

brenda

Bos taurus

-

733841

-

-

brenda

Bos taurus

a mixture of trimeric Gq and G11, referred to as Gq/11

644103

-

-

brenda

Bos taurus

alpha-subunit of transducin

644106

-

-

brenda

Bos taurus

Go and Gs

644093

-

-

brenda

Bos taurus

Go: a G protein with unknown function

644092, 644099

-

-

brenda

Bos taurus

Goalpha

644095, 644108

-

-

brenda

Bos taurus

photoreceptor G protein transducin

644098

-

-

brenda

Bos taurus

taste-specific G protein, gustducin

644097

-

-

brenda

Glycine max

-

734981, 757967

-

-

brenda

Glycine max

cv. Jack Seeds

720561

-

-

brenda

Glycine max

cv. Jack Seeds, four soybean Galpha proteins GmGalpha1-4

720019

-

-

brenda

Homo sapiens

-

644099, 644104, 644107, 644110, 656036, 656349, 674043, 676111, 676113, 676909, 697230, 700481, 701012, 719765, 734359

-

-

brenda

Homo sapiens

-

735104

P30679

SwissProt

brenda

Homo sapiens

-

758385

-

-

brenda

Homo sapiens

transducin GTPase activity

644091, 644092

-

-

brenda

Rattus norvegicus

-

644099, 644105, 654813, 656589, 700481

-

-

brenda

Rattus norvegicus

Gi1alpha, Gi2alpha anf Gi3alpha

644100

-

-

brenda

Rattus norvegicus

Gialpha1

644109

-

-

brenda

Rattus norvegicus

Sprague-Dawley rat

676093

-

-

brenda