Any feedback?
Literature summary for 3.6.5.1 extracted from
- Pasteurella multocida toxin activates Gbetagamma dimers of heterotrimeric G proteins (2009), Cell. Signal., 21, 551-558.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Pasteurella multocida toxin | - |
Homo sapiens | |
| Pasteurella multocida toxin | dependent on cycling of G betagamma-subunits | Mus musculus | |
| phenylephrine | - |
Mus musculus |  |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| G208A | mutant of G alphaQ, unable to release G betagamma-subunits | Mus musculus |
| I25A/E26A | mutant of G alphaQ, lost ability to bind the G betagamma-subunits | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| YM-254890 | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HEK-293 cell | - |
Homo sapiens | - |
| MEF cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Mus musculus | GDP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| G alpha11 | - |
Mus musculus |
| G alphaQ | - |
Mus musculus |
| G betagamma | - |
Homo sapiens |
| heterotrimeric G protein family | - |
Mus musculus |
| heterotrimeric G protein family | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
