3.5.4.12: dCMP deaminase

This is an abbreviated version!
For detailed information about dCMP deaminase, go to the full flat file.

Word Map on EC 3.5.4.12

3.5.4.12

thymidine

dttp

thymidylate

ribonucleotide

deoxyribonucleotide

tetrahydrouridine

deoxyuridine

deaminases

deoxythymidine

ara-ctp

1-beta-d-arabinofuranosylcytosine

pharmacology

medicine

Reaction

Synonyms

2-deoxycytidylate deaminase, 5-mdCMP deaminase, 5-methyldeoxycytidine monophosphate deaminase, DCD, DCD1, dCDA, dCMP deaminase, dCMP-aminohydrolase, dCMP-dCTP deaminase, dCMPase, dCMPD, deaminase, deoxycytidylate, deoxy-CMP-deaminase, deoxycytidine deaminase, deoxycytidine monophosphate deaminase, deoxycytidine nucleotide deaminase, deoxycytidine-5'-monophosphate aminohydrolase, deoxycytidine-5'-monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidylate aminohydrolase, deoxycytidylate deaminase, ST2 protein, STRIPE2, T2-dCMP deaminase, T2-deoxycytidylate deaminase, T2-phage deoxycytidylate deaminase, T4-dCMP deaminase, T4-deaminase, T4-phage deoxycytidylate deaminase

ECTree

3 Hydrolases

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.5.4 In cyclic amidines

3.5.4.12 dCMP deaminase

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Results	in table
118	Activating Compound
977	AA Sequence
6	Application
1	CAS Registry Number
12	Cloned(Commentary)
1	Cofactor
6	Crystallization (Commentary)
264	Disease/ Diagnostics
3	General Information
44	General Stability
129	Inhibitors
6	Ki Value [mM]
59	KM Value [mM]
1	Localization
63	Metals/Ions
30	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
83	Organism
5	Pathway
12	PDB ID
31	pH Optimum
4	pH Range
20	Protein Variants
33	Purification (Commentary)
90	Reaction
1	Reaction Type
71	Reference
3	Renatured (Commentary)
46	Source Tissue
19	Specific Activity [micromol/min/mg]
16	Storage Stability
238	Substrates and Products (Substrate)
43	Subunits
49	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Temperature Stability [°C]
12	Turnover Number [1/s]

KM Value

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KM Value on EC 3.5.4.12 - dCMP deaminase

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0.1

5-methyl-dCMP

Escherichia phage T2

pH 8.3, in the presence of dCTP or 5-hydroxymethyl-dCTP. Decreasing the pH to 6.0 lowers the apparent Km

289004

0.5 - 12

CMP

3 entries

0.021 - 1

dCMP

21 entries

0.26

dCMP-Hg-S-CH2-CH2-OH

Equus asinus

289003

0.64

dCTP

Paramecium bursaria Chlorella virus 1

O41078

pH 9.5, 42°C

688732

0.347 - 0.467

deoxycytidine

4 entries

additional information

28 entries