3.5.4.12: dCMP deaminase

This is an abbreviated version!
For detailed information about dCMP deaminase, go to the full flat file.

Reaction

Synonyms

2-deoxycytidylate deaminase, 5-mdCMP deaminase, 5-methyldeoxycytidine monophosphate deaminase, DCD, DCD1, dCDA, dCMP deaminase, dCMP-aminohydrolase, dCMP-dCTP deaminase, dCMPase, dCMPD, deaminase, deoxycytidylate, deoxy-CMP-deaminase, deoxycytidine deaminase, deoxycytidine monophosphate deaminase, deoxycytidine nucleotide deaminase, deoxycytidine-5'-monophosphate aminohydrolase, deoxycytidine-5'-monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidylate aminohydrolase, deoxycytidylate deaminase, ST2 protein, STRIPE2, T2-dCMP deaminase, T2-deoxycytidylate deaminase, T2-phage deoxycytidylate deaminase, T4-dCMP deaminase, T4-deaminase, T4-phage deoxycytidylate deaminase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.12 dCMP deaminase

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Results	in table
118	Activating Compound
977	AA Sequence
6	Application
1	CAS Registry Number
12	Cloned(Commentary)
1	Cofactor
6	Crystallization (Commentary)
264	Disease/ Diagnostics
3	General Information
44	General Stability
129	Inhibitors
6	Ki Value [mM]
59	KM Value [mM]
1	Localization
63	Metals/Ions
30	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
83	Organism
5	Pathway
12	PDB ID
31	pH Optimum
4	pH Range
20	Protein Variants
33	Purification (Commentary)
90	Reaction
1	Reaction Type
71	Reference
3	Renatured (Commentary)
46	Source Tissue
19	Specific Activity [micromol/min/mg]
16	Storage Stability
238	Substrates and Products (Substrate)
43	Subunits
49	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Temperature Stability [°C]
12	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.5.4.12 - dCMP deaminase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.03

Lactobacillus acidophilus

-

-

289011

0.37

Cricetinae

-

-

289008

10

Homo sapiens

-

-

288999

121

Tequatrovirus T4

-

mutant R115Q

289015

220

Tequatrovirus T4

-

wild-type

289015

23

Equus asinus

-

substrate: dCMP-Hg-S-CH2-CH2-OH

289003

430

Escherichia phage T2

-

-

289004, 289009

481

Homo sapiens

-

-

289018

500

Homo sapiens

-

HeLa cells

289020

6.36

Bacillus subtilis

-

-

289005

720

Equus asinus

-

-

288998

730

Equus asinus

-

-

289012

820

Equus asinus

-

substrate: dCMP

289003

90 - 100

Tequatrovirus T4

-

mutant R115E

289015

additional information

4 entries

additional information

Equus asinus

-

-

288998

additional information

Equus asinus

-

-

289003

additional information

Rattus norvegicus

-

-

667541

additional information

Tequatrovirus T4

-

mutants R115E and R115Q possessing specific activity about 40-50% of wild-type enzyme

289015