3.5.4.12: dCMP deaminase

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For detailed information about dCMP deaminase, go to the full flat file.

Reaction

Synonyms

2-deoxycytidylate deaminase, 5-mdCMP deaminase, 5-methyldeoxycytidine monophosphate deaminase, DCD, DCD1, dCDA, dCMP deaminase, dCMP-aminohydrolase, dCMP-dCTP deaminase, dCMPase, dCMPD, deaminase, deoxycytidylate, deoxy-CMP-deaminase, deoxycytidine deaminase, deoxycytidine monophosphate deaminase, deoxycytidine nucleotide deaminase, deoxycytidine-5'-monophosphate aminohydrolase, deoxycytidine-5'-monophosphate deaminase, deoxycytidine-5'-phosphate deaminase, deoxycytidylate aminohydrolase, deoxycytidylate deaminase, ST2 protein, STRIPE2, T2-dCMP deaminase, T2-deoxycytidylate deaminase, T2-phage deoxycytidylate deaminase, T4-dCMP deaminase, T4-deaminase, T4-phage deoxycytidylate deaminase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.12 dCMP deaminase

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Results	in table
118	Activating Compound
977	AA Sequence
6	Application
1	CAS Registry Number
12	Cloned(Commentary)
1	Cofactor
6	Crystallization (Commentary)
264	Disease/ Diagnostics
3	General Information
44	General Stability
129	Inhibitors
6	Ki Value [mM]
59	KM Value [mM]
1	Localization
63	Metals/Ions
30	Molecular Weight [Da]
87	Natural Substrates/ Products (Substrates)
83	Organism
5	Pathway
12	PDB ID
31	pH Optimum
4	pH Range
20	Protein Variants
33	Purification (Commentary)
90	Reaction
1	Reaction Type
71	Reference
3	Renatured (Commentary)
46	Source Tissue
19	Specific Activity [micromol/min/mg]
16	Storage Stability
238	Substrates and Products (Substrate)
43	Subunits
49	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Temperature Stability [°C]
12	Turnover Number [1/s]

Cloned

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Cloned on EC 3.5.4.12 - dCMP deaminase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

2 entries

cDNA from HeLa cells can be expressed in an active form

Homo sapiens

-

289018

cloned and amplified in a high-expression system, expression in Escherichia coli strain BL21-DE3/pLysS

Tequatrovirus T4

-

289017

cloned and overexpressed in Escherichia coli strain BL21-DE3/pLysS

Homo sapiens

-

289017

expressed in Escherichia coli BL21(DE3) cells

Cyanophage S-TIM5

H6WFU3

734322

expressed in onion epidermal cells and rice protoplasts

Oryza sativa

-

734401

expression in Escherichia coli BL21 (DE3)

Oryza sativa

Q5JN09

757330

expression of mutant R115E in Escherichia coli

Tequatrovirus T4

-

667587

expression of wild-type and mutant enzymes in Escherichia coli

Tequatrovirus T4

-

289015

ORF A596R, DNA and amino acid sequence determination and analysis, expression of the His6-tagged enzyme in Escherichia coli strain DH5MCR, phylogenetic analysis

Paramecium bursaria Chlorella virus 1

O41078

688732

overexpression of His-tagged enzyme in Escherichia coli strain BL21(DE3)

Streptococcus mutans

-

688405

-

Tequatrovirus T4

-

289020

-

Schistosoma mansoni

-

756103