3.4.23.45: memapsin 1
This is an abbreviated version!
For detailed information about memapsin 1, go to the full flat file.
Word Map on EC 3.4.23.45
Reaction
broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein =
Synonyms
aspartic protease BACE2, BACE 2, BACE-1 homologue, BACE-2, BACE2, beta site APP cleaving enzyme, beta-amyloid precursor protein cleavage enzyme 2, beta-secretase, beta-secretase 2, beta-site Alzheimer's amyloid precurser protein cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, beta-site amyloid precursor protein-cleaving enzyme 2, beta-site APP cleaving enzyme, beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, down region aspartic protease, DRAP, memapsin-1, memapsin1, membrane aspartic protease of the pepsin family, More, protease ASP1, theta-secretase
ECTree
3.4.23.45 memapsin 1Advanced search results
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results (Synonyms
Synonyms on EC 3.4.23.45 - memapsin 1
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
aspartic protease BACE2
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-
-
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BACE-2
BACE2
beta-secretase
beta-secretase 2
beta-site Alzheimer's amyloid precurser protein cleaving enzyme 2
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-
-
-
beta-site amyloid precursor protein cleaving enzyme 2
beta-site APP-cleaving enzyme 2
down region aspartic protease
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protease ASP1
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-
-
-
theta-secretase
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preferential cleavage of the amyloid precursor protein downstream of the alpha-site of A-beta
additional information
BACE2
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-
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-
BACE2
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homologue to BACE1, which cleaves amyloid precursor protein at the beta site but preferably after Phe690 or Phe691
beta-secretase
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beta-secretase 2
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beta-site amyloid precursor protein cleaving enzyme 2
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-
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beta-site APP-cleaving enzyme 2
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