3.4.23.45: memapsin 1
This is an abbreviated version!
For detailed information about memapsin 1, go to the full flat file.
Word Map on EC 3.4.23.45
Reaction
broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein =
Synonyms
aspartic protease BACE2, BACE 2, BACE-1 homologue, BACE-2, BACE2, beta site APP cleaving enzyme, beta-amyloid precursor protein cleavage enzyme 2, beta-secretase, beta-secretase 2, beta-site Alzheimer's amyloid precurser protein cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, beta-site amyloid precursor protein-cleaving enzyme 2, beta-site APP cleaving enzyme, beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, down region aspartic protease, DRAP, memapsin-1, memapsin1, membrane aspartic protease of the pepsin family, More, protease ASP1, theta-secretase
ECTree
3.4.23.45 memapsin 1Advanced search results
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Expression on EC 3.4.23.45 - memapsin 1
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EXPRESSION 
ORGANISM
UNIPROT
LITERATURE
BACE2 mRNA levels are downregulated at 6, 12, and 24 h exposure to 0.01 mM AlCl3 and 0.002 mM amyloid beta peptide
BACE2 mRNA levels are significantly increased after 1 and 3 h exposure to 0.01 mM AlCl3 and 0.002 mM amyloid beta peptide
neither treatment with 0.002 mM of the Abeta(25-35) fragment nor with 0.01 mM AlCl3 alone influences BACE2 gene mRNA after 24 h
