Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | BACE-2 exhibits secretase activity with cleavage in the middle of the amyloid peptide domain at amino acids 19 and 20 generating a carboxy-terminal fragment of 79 residues, and does not contribute to the process of amyloid peptide generation, BACE-2 can cleave at the beta-site, but consistent with its different substrate specificity, does not cleave a preferred peptide-based BACE-1 substrate | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BACE-1 homologue | - |
Homo sapiens |
BACE-2 | - |
Homo sapiens |
beta site APP cleaving enzyme | - |
Homo sapiens |
beta-secretase | - |
Homo sapiens |