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3.4.23.45: memapsin 1

This is an abbreviated version!
For detailed information about memapsin 1, go to the full flat file.

Word Map on EC 3.4.23.45

Reaction

broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein =

Synonyms

aspartic protease BACE2, BACE 2, BACE-1 homologue, BACE-2, BACE2, beta site APP cleaving enzyme, beta-amyloid precursor protein cleavage enzyme 2, beta-secretase, beta-secretase 2, beta-site Alzheimer's amyloid precurser protein cleaving enzyme 2, beta-site amyloid precursor protein cleaving enzyme 2, beta-site amyloid precursor protein-cleaving enzyme 2, beta-site APP cleaving enzyme, beta-site APP cleaving enzyme 2, beta-site APP-cleaving enzyme 2, down region aspartic protease, DRAP, memapsin-1, memapsin1, membrane aspartic protease of the pepsin family, More, protease ASP1, theta-secretase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.45 memapsin 1

Sequence

Sequence on EC 3.4.23.45 - memapsin 1

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
BACE2_HUMAN
518
1
56180
Swiss-Prot
Secretory Pathway (Reliability: 1)
BACE2_MOUSE
514
2
55800
Swiss-Prot
Secretory Pathway (Reliability: 1)
BACE2_RAT
514
1
55858
Swiss-Prot
Secretory Pathway (Reliability: 1)
Q6PB20_XENLA
499
1
54804
TrEMBL
Secretory Pathway (Reliability: 1)
A0A061IC94_CRIGR
387
1
43079
TrEMBL
other Location (Reliability: 2)
A0A061I5J9_CRIGR
430
1
47351
TrEMBL
other Location (Reliability: 2)
A0A2P6PAH5_ROSCH
89
0
9755
TrEMBL
other Location (Reliability: 3)
B7PWI2_IXOSC
280
0
30926
TrEMBL
other Location (Reliability: 4)
B3KNE8_HUMAN
355
1
39152
TrEMBL
other Location (Reliability: 5)
Q7T0Y2_XENLA
500
1
54723
TrEMBL
Secretory Pathway (Reliability: 1)
B4F734_XENTR
499
2
54547
TrEMBL
Secretory Pathway (Reliability: 1)
Q5XJ89_DANRE
372
0
40577
TrEMBL
Secretory Pathway (Reliability: 2)
X4Z0F5_DANRE
462
0
50041
TrEMBL
other Location (Reliability: 2)