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3.4.16.5: carboxypeptidase C

This is an abbreviated version!
For detailed information about carboxypeptidase C, go to the full flat file.

Word Map on EC 3.4.16.5

Reaction

release of a C-terminal amino acid with broad specificity =

Synonyms

A-type metallocarboxypeptidase, acidic serine carboxypeptidase, AtCPY, BRS1, carboxypeptidase a, carboxypeptidase A4, carboxypeptidase C, Carboxypeptidase II, carboxypeptidase Y, carboxypeptidase YSCY, carboxypeptidase-Y, Case, CatA, CathA, cathepsin A, CaY, CP-MI, CP-MIII, CP-WIII, CPA4, CPase, CPC, CPD-Y, CPW, CPY, Cpy1p, CTSA, Cxp1, deamidase, EC 3.4.12.1, EC 3.4.16.1, EC 3.4.16.3, hCath A, HPP, lysosomal carboxypeptidase A, lysosomal protective protein, MO54, More, MpiCP-1, MpiCP-2, Phaseolin, PpcA, PRC1, proCPY, protective protein cathepsin A, protective protein/cathepsin A, retinoid-inducible serine carboxypeptidase, SCP, Scpep1, Ser carboxypeptidase, Ser carboxypeptidase-like protein, serine carboxypeptidase, serine carboxypeptidase 1, serine carboxypeptidase I, serine carboxypeptidase Scpep1, SmSCP-1, TcCBP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.16 Serine-type carboxypeptidases
                3.4.16.5 carboxypeptidase C

Substrates Products

Substrates Products on EC 3.4.16.5 - carboxypeptidase C

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5-dimethylaminonaphthalene-1-sulfonyl-Phe-Leu-Arg + H2O
5-dimethylaminonaphthalene-1-sulfonyl-Phe-Leu + Arg
show the reaction diagram
-
-
-
?
9-(R)-4'-(R)-[[[(S)-1-[(ethoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]-2'-fluoro-1'-furanyladenine + H2O
?
show the reaction diagram
-
-
-
-
?
9-fluorenylmethoxycarbonyl-Glu-Ala + H2O
9-fluorenylmethoxycarbonyl-Glu + Ala
show the reaction diagram
-
-
-
-
?
9-fluorenylmethoxycarbonyl-Glu-Glu-Ala + H2O
9-fluorenylmethoxycarbonyl-Glu-Glu + Ala
show the reaction diagram
-
-
-
-
?
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Ala + H2O
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu + Ala
show the reaction diagram
-
-
-
-
?
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Glu-Ala + H2O
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Glu + Ala
show the reaction diagram
-
-
-
-
?
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Glu-Glu-Ala + H2O
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Glu-Glu + Ala
show the reaction diagram
-
-
-
-
?
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Glu-Glu-Glu-Ala + H2O
9-fluorenylmethoxycarbonyl-Glu-Glu-Glu-Glu-Glu-Glu + Ala
show the reaction diagram
-
-
-
-
?
9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]phenoxyphosphinyl]methoxy]-propyl]adenine + H2O
?
show the reaction diagram
-
-
-
-
?
acetyl-Phe ethyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
acetyl-Phe-Leu + H2O
acetyl-Phe + Leu
show the reaction diagram
-
-
-
-
?
acetyl-Phe-NH2 + H2O
?
show the reaction diagram
-
-
-
-
?
Acetyl-Tyr ethyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
acetyl-Tyr-ethyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
adrenocorticotropic hormone fragment 7-38 + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Ala benzyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Ala-OGly + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Ala-OMe + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Arg-4-nitroanilide + H2O
benzoyl-Arg + 4-nitrolaniline
show the reaction diagram
benzoyl-Gly benzyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-Arg + H2O
benzoyl-Gly + Arg
show the reaction diagram
benzoyl-Gly-beta-phenyllactate + H2O
?
show the reaction diagram
benzoyl-Gly-Lys + H2O
benzoyl-Gly + Lys
show the reaction diagram
-
isoenzyme MpiCP-2
-
-
?
benzoyl-Gly-OEt + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-OGly + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-OMe + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-OPhe + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly-Phe + H2O
benzoyl-Gly + Phe
show the reaction diagram
-
-
-
-
?
benzoyl-L-Tyr-4-nitroanilide + H2O
benzoyl-Tyr + 4-nitroaniline
show the reaction diagram
benzoyl-L-tyrosine-p-nitroanilide + H2O
benzoyl-L-tyrosine + p-nitroaniline
show the reaction diagram
-
-
-
-
?
benzoyl-Phe-Gly + H2O
benzoyl-Phe + Gly
show the reaction diagram
-
-
-
-
?
benzoyl-Phe-OGly + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Phe-OMe + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Tyr-4-nitroanilide + H2O
benzoyl-Tyr + 4-nitroaniline
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Ala-Ala + H2O
benzyloxycarbonyl-Ala + Ala
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Ala-Glu + H2O
benzyloxycarbonyl-Ala + Glu
show the reaction diagram
Benzyloxycarbonyl-Ala-Leu + H2O
Benzyloxycarbonyl-Ala + Leu
show the reaction diagram
-
-
-
-
?
Benzyloxycarbonyl-Ala-Phe + H2O
Benzyloxycarbonyl-Ala + Phe
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Arg-Pro + H2O
benzyloxycarbonyl-Arg + Pro
show the reaction diagram
Citrus sp.
-
-
-
-
?
benzyloxycarbonyl-Glu-Leu + H2O
benzyloxycarbonyl-Glu + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Glu-Phe + H2O
benzyloxycarbonyl-Glu + Phe
show the reaction diagram
Benzyloxycarbonyl-Glu-Tyr + H2O
Benzyloxycarbonyl-Glu + Tyr
show the reaction diagram
benzyloxycarbonyl-Gly-Arg + H2O
benzyloxycarbonyl-Gly + Arg
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Gly-Glu + H2O
benzyloxycarbonyl-Gly + Glu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Gly-Gly + H2O
benzyloxycarbonyl-Gly + Gly
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Gly-Gly-Phe + H2O
benzyloxycarbonyl-Gly-Gly + Phe
show the reaction diagram
-
-
-
-
?
Benzyloxycarbonyl-Gly-Leu + H2O
Benzyloxycarbonyl-Gly + Leu
show the reaction diagram
benzyloxycarbonyl-Gly-Met + H2O
benzyloxycarbonyl-Gly + Met
show the reaction diagram
-
19% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
Benzyloxycarbonyl-Gly-Phe + H2O
Benzyloxycarbonyl-Gly + Phe
show the reaction diagram
benzyloxycarbonyl-Gly-Pro + H2O
benzyloxycarbonyl-Gly + Pro
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Gly-Pro-Leu-Gly + H2O
benzyloxycarbonyl-Gly-Pro-Leu + Gly
show the reaction diagram
benzyloxycarbonyl-Gly-Pro-Leu-Gly-Pro + H2O
benzyloxycarbonyl-Gly-Pro-Leu-Gly + Pro
show the reaction diagram
-
3% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
Benzyloxycarbonyl-Gly-Val + H2O
Benzyloxycarbonyl-Gly + Val
show the reaction diagram
-
24% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
benzyloxycarbonyl-His-Leu + H2O
benzyloxycarbonyl-His + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-His-Phe + H2O
benzyloxycarbonyl-His + Phe
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-His-Tyr + H2O
benzyloxycarbonyl-His + Tyr
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Ile-Leu + H2O
benzyloxycarbonyl-Ile + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-L-Phe-L-Leu + H2O
benzyloxycarbonyl-L-Phe + L-Leu
show the reaction diagram
-
-
-
?
benzyloxycarbonyl-L-phenylalanyl-L-leucine + H2O
benzyloxycarbonyl-Phe + Leu
show the reaction diagram
-
-
-
?
benzyloxycarbonyl-Leu-Leu + H2O
benzyloxycarbonyl-Leu + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Leu-Phe + H2O
benzyloxycarbonyl-Leu + Phe
show the reaction diagram
benzyloxycarbonyl-Nle-Leu + H2O
benzyloxycarbonyl-Nle + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Ala + H2O
benzyloxycarbonyl-Phe + Ala
show the reaction diagram
benzyloxycarbonyl-Phe-beta-Ala + H2O
benzyloxycarbonyl-Phe + beta-Ala
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Glu + H2O
benzyloxycarbonyl-Phe + Glu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Gly + H2O
benzyloxycarbonyl-Phe + Gly
show the reaction diagram
benzyloxycarbonyl-Phe-His + H2O
benzyloxycarbonyl-Phe + His
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Leu + H2O
benzyloxycarbonyl-Phe + Leu
show the reaction diagram
benzyloxycarbonyl-Phe-NH2 + H2O
?
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Phe + H2O
benzyloxycarbonyl-Phe + Phe
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Pro + H2O
benzyloxycarbonyl-Phe + Pro
show the reaction diagram
Benzyloxycarbonyl-Phe-Tyr + H2O
Benzyloxycarbonyl-Phe + Tyr
show the reaction diagram
benzyloxycarbonyl-Phe-Tyr-Gly + H2O
benzyloxycarbonyl-Phe-Tyr + Gly
show the reaction diagram
-
172% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
benzyloxycarbonyl-Phe-Tyr-Leu + H2O
benzyloxycarbonyl-Phe-Tyr + Leu
show the reaction diagram
-
120% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
benzyloxycarbonyl-Pro-Leu + H2O
benzyloxycarbonyl-Pro + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Pro-Leu-Gly + H2O
benzyloxycarbonyl-Pro-Leu + Gly
show the reaction diagram
-
isoenzyme MpiCP-2
-
-
?
benzyloxycarbonyl-Ser-Leu + H2O
benzyloxycarbonyl-Ser + Leu
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Tyr-Glu + H2O
benzyloxycarbonyl-Tyr + Glu
show the reaction diagram
benzyloxycarbonyl-Tyr-Gly + H2O
benzyloxycarbonyl-Tyr + Gly
show the reaction diagram
-
188% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
benzyloxycarbonyl-Tyr-Phe + H2O
benzyloxycarbonyl-Tyr + Phe
show the reaction diagram
-
201% activity compared to benzyloxycarbonyl-Glu-Tyr
-
-
?
benzyloxycarbonyl-Val-Leu + H2O
benzyloxycarbonyl-Val + Leu
show the reaction diagram
-
-
-
-
?
bombesin + H2O
?
show the reaction diagram
-
-
-
-
?
carboxypropionyl-Phe-4-nitroanilide + H2O
carboxypropionyl-Phe + 4-nitroaniline
show the reaction diagram
CBZ-Phe-Leu + H2O
N-benzyloxycarbonyl-L-Phe + L-leucine
show the reaction diagram
-
-
-
?
corn gluten + H2O
?
show the reaction diagram
-
-
-
-
?
corticotropin-releasing factor fragment 6-33 + H2O
?
show the reaction diagram
-
-
-
-
?
cyclo-statherin Q-37 + H2O
?
show the reaction diagram
-
-
-
-
?
endothelin + H2O
?
show the reaction diagram
-
-
-
-
?
endothelin I + H2O
endothelin(1-20) + Trp
show the reaction diagram
furylacryloyl-Ala-Arg + H2O
furylacryloyl-Ala + Arg
show the reaction diagram
furylacryloyl-Ala-Glu + H2O
furylacryloyl-Ala + Glu
show the reaction diagram
-
-
-
-
?
furylacryloyl-Ala-Leu + H2O
furylacryloyl-Ala + Leu
show the reaction diagram
-
-
-
-
?
furylacryloyl-Ala-Lys + H2O
furylacryloyl-Ala + Lys
show the reaction diagram
furylacryloyl-Arg-Leu + H2O
furylacryloyl-Arg + Leu
show the reaction diagram
-
preferred substrate
-
-
?
furylacryloyl-Lys-Ala + H2O
furylacryloyl-Lys + Ala
show the reaction diagram
-
-
-
-
?
furylacryloyl-Lys-Leu + H2O
furylacryloyl-Lys + leu
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe ethyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-Ala + H2O
furylacryloyl-Phe + Ala
show the reaction diagram
furylacryloyl-Phe-Gly + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-Leu + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-Leu + H2O
furylacryloyl-Phe + Leu
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-NHEt + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-OGly + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-OGly-OH + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-OMe + H2O
?
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-Phe + H2O
furylacryloyl-Phe + Phe
show the reaction diagram
-
-
-
-
?
furylacryloyl-Phe-Val + H2O
furylacryloyl-Phe + Val
show the reaction diagram
-
-
-
-
?
FVNQHLCGSHLV + H2O
FVNQHLCGSH + L-Leu-L-Val + L-Val
show the reaction diagram
-
-
-
-
?
FVNQHLCGSHLVEAL + H2O
FVNQHLCGSHLVE + L-Ala-L-Leu + L-Leu
show the reaction diagram
-
-
-
-
?
Glu-Asp-Glu-Phe-Phe-Leu-Ala + H2O
Glu-Asp-Glu-Phe-Phe-Leu + Ala
show the reaction diagram
-
-
-
?
Glucagon + H2O
?
show the reaction diagram
-
-
-
-
?
hippuryl-beta-phenyl lactate + H2O
?
show the reaction diagram
-
-
-
-
?
isoaspartyl peptides + H2O
isoaspartyl dipeptides
show the reaction diagram
-
-
-
?
Leu-4-nitroanilide + H2O
Leu + 4-nitroaniline
show the reaction diagram
lysosomal neuraminidase-1 + H2O
?
show the reaction diagram
lysosomal neuraminidase-1 gains full catalytic activity in the lysosome through its binding to PPCA
-
-
?
N-((S)-5-amino-5-(carbamoyl)pentyl)-3-(aminooxymethyl)benzamide + H2O
?
show the reaction diagram
-
-
-
?
N-(2-furanacryloyl)-Phe-Phe + H2O
N-(2-furanacryloyl)-Phe + Phe
show the reaction diagram
-
-
-
-
?
N-(4-methoxyphenyl-azoformyl)-L-Phe-OH + H2O
?
show the reaction diagram
-
-
-
-
?
N-acetyl-renin tetradecapeptide + H2O
?
show the reaction diagram
-
-
-
-
?
N-benzoyl-L-tyrosine-p-nitroanilide + H2O
N-benzoyl-L-Tyr + p-nitroaniline
show the reaction diagram
-
-
-
-
?
N-benzoyl-L-tyrosine-p-nitroanilide + H2O
N-benzoyl-L-tyrosine + p-nitroaniline
show the reaction diagram
N-carbobenzoxy-L-Phe-L-Ala + H2O
N-carbobenzoxy-L-Phe + L-Ala
show the reaction diagram
-
-
-
-
?
ochratoxin A + H2O
ochratoxin alpha
show the reaction diagram
oxidized insulin B + H2O
?
show the reaction diagram
-
-
-
-
?
pancreatic carboxypeptidase A + H2O
hydrolyzed carboxypeptidase A + C-terminal amino acid
show the reaction diagram
-
-
-
?
pancreatic carboxypeptidase B + H2O
hydrolyzed pancreatic carboxypeptidase B + C-terminal amino acid
show the reaction diagram
-
-
-
?
pepsin-digested soy protein + H2O
?
show the reaction diagram
-
-
-
-
?
phytochelatin + H2O
phytochelatin 2 + ?
show the reaction diagram
poly-alpha-L-aspartic acid + H2O
?
show the reaction diagram
-
slowly
-
-
?
poly-alpha-L-glutamic acid + H2O
glutamic acid
show the reaction diagram
-
-
-
?
succinyl-L-Ile-L-Ile-L-Trp-7-amido-4-methylcoumarin + H2O
succinyl-L-Ile-L-Ile-L-Trp + 7-amino-4-methylcoumarin
show the reaction diagram
-
-
-
-
?
Tamm-Horsfall glycoprotein + H2O
?
show the reaction diagram
-
-
-
-
?
trypsin-digested casein + H2O
?
show the reaction diagram
-
-
-
-
?
additional information
?
-