Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.16.5 extracted from

  • Peschke, B.; Bak, S.
    Controlled coupling of peptides at their C-termini (2009), Peptides, 30, 689-698.
    View publication on PubMed

Application

Application Comment Organism
molecular biology a method is described exploiting the possibility to attach different reactive handles to their C-termini using a reaction catalyzed by CPY. It is possible to attach pairs of reaction handles which can react with each other to each of the peptides to be coupled. In a second step, the two modified peptides can be linked together by a chemical reaction, such as an oxime-forming reaction or a copper(I) catalyzed (2+3)-cycloaddition reaction of an azide with an alkyne Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P00729
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Glu-Asp-Glu-Phe-Phe-Leu-Ala + H2O
-
Saccharomyces cerevisiae Glu-Asp-Glu-Phe-Phe-Leu + Ala
-
?
N-((S)-5-amino-5-(carbamoyl)pentyl)-3-(aminooxymethyl)benzamide + H2O
-
Saccharomyces cerevisiae ?
-
?

Synonyms

Synonyms Comment Organism
CPY
-
Saccharomyces cerevisiae