3.4.16.5: carboxypeptidase C

This is an abbreviated version!
For detailed information about carboxypeptidase C, go to the full flat file.

Reaction

release of a C-terminal amino acid with broad specificity =

Synonyms

A-type metallocarboxypeptidase, acidic serine carboxypeptidase, AtCPY, BRS1, carboxypeptidase a, carboxypeptidase A4, carboxypeptidase C, Carboxypeptidase II, carboxypeptidase Y, carboxypeptidase YSCY, carboxypeptidase-Y, Case, CatA, CathA, cathepsin A, CaY, CP-MI, CP-MIII, CP-WIII, CPA4, CPase, CPC, CPD-Y, CPW, CPY, Cpy1p, CTSA, Cxp1, deamidase, EC 3.4.12.1, EC 3.4.16.1, EC 3.4.16.3, hCath A, HPP, lysosomal carboxypeptidase A, lysosomal protective protein, MO54, More, MpiCP-1, MpiCP-2, Phaseolin, PpcA, PRC1, proCPY, protective protein cathepsin A, protective protein/cathepsin A, retinoid-inducible serine carboxypeptidase, SCP, Scpep1, Ser carboxypeptidase, Ser carboxypeptidase-like protein, serine carboxypeptidase, serine carboxypeptidase 1, serine carboxypeptidase I, serine carboxypeptidase Scpep1, SmSCP-1, TcCBP

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.16 Serine-type carboxypeptidases

                3.4.16.5 carboxypeptidase C

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Results	in table
15	Activating Compound
133	AA Sequence
4	Application
1	CAS Registry Number
17	Cloned(Commentary)
1	Cofactor
9	Crystallization (Commentary)
369	Disease/ Diagnostics
1	Expression
10	General Information
8	General Stability
57	IC50 Value
221	Inhibitors
27	Ki Value [mM]
126	KM Value [mM]
28	Localization
22	Metals/Ions
40	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
6	Organic Solvent Stability
204	Organism
23	PDB ID
20	pH Optimum
6	pH Range
20	pH Stability
7	pI Value
24	Posttranslational Modification
77	Protein Variants
25	Purification (Commentary)
1	Reaction
3	Reaction Type
127	Reference
2	Renatured (Commentary)
66	Source Tissue
9	Specific Activity [micromol/min/mg]
2	Storage Stability
269	Substrates and Products (Substrate)
13	Subunits
152	Synonyms
12	Temperature Optimum [°C]
2	Temperature Range [°C]
13	Temperature Stability [°C]
122	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.4.16.5 - carboxypeptidase C

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SYNONYM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

A-type metallocarboxypeptidase

Homo sapiens

-

-

678293

acidic serine carboxypeptidase

Todarodes pacificus

-

-

679935

AtCPY

Arabidopsis sp.

-

-

666722

BRS1

Arabidopsis sp.

-

-

665664

carboxypeptidase a

2 entries

carboxypeptidase A4

Homo sapiens

-

-

678293

carboxypeptidase C

2 entries

Carboxypeptidase II

Triticum aestivum

-

-

665316

carboxypeptidase Y

10 entries

carboxypeptidase YSCY

-

-

-

-

carboxypeptidase-Y

Arabidopsis thaliana

-

-

682421

Case

Saccharomyces cerevisiae

-

-

680178

CatA

2 entries

CathA

2 entries

cathepsin A

4 entries

CaY

Saccharomyces cerevisiae

-

-

677412

CP-MI

-

-

-

-

CP-MIII

-

-

-

-

CP-WIII

-

-

-

-

CPA4

Homo sapiens

-

-

678293

CPase

Todarodes pacificus

-

-

679935

CPC

2 entries

CPD-Y

Saccharomyces cerevisiae

-

-

681641

CPW

Triticum aestivum

-

-

665316

CPY

9 entries

Cpy1p

Schizosaccharomyces pombe

-

-

704781

CTSA

3 entries

Cxp1

Hordeum vulgare

-

-

665030

deamidase

-

-

-

-

EC 3.4.12.1

-

-

formerly

-

EC 3.4.16.1

Homo sapiens

P10619

formerly

702451

EC 3.4.16.3

-

-

formerly

-

hCath A

Homo sapiens

-

-

665316

HPP

Homo sapiens

P10619

-

732129

lysosomal carboxypeptidase A

2 entries

lysosomal protective protein

2 entries

MO54

-

-

-

-

MpiCP-1

Monascus pilosus

-

-

665932, 665936

MpiCP-2

Monascus pilosus

-

-

665932

Phaseolin

2 entries

PpcA

3 entries

PRC1

Saccharomyces cerevisiae

P00729

-

753050

proCPY

Saccharomyces cerevisiae

-

-

731493

protective protein cathepsin A

Mus musculus

-

-

680391

protective protein/cathepsin A

2 entries

retinoid-inducible serine carboxypeptidase

Mus musculus

-

-

665905

SCP

Arabidopsis thaliana

-

-

682421

Scpep1

2 entries

Ser carboxypeptidase

Arabidopsis thaliana

-

-

682421

Ser carboxypeptidase-like protein

Arabidopsis thaliana

-

SCPL, SCPL proteins bear the trademark Ser-Asp-His catalytic triad along with other sequence features that are characteristic of known Ser carboxypeptidases

682421

serine carboxypeptidase

5 entries

serine carboxypeptidase 1

Mus musculus

Q920A5

-

708470

serine carboxypeptidase I

2 entries

serine carboxypeptidase Scpep1

Mus musculus

-

-

665905

SmSCP-1

Sitodiplosis mosellana

-

-

665196

TcCBP

2 entries

additional information

4 entries

carboxypeptidase a

Phaffia rhodozyma

-

-

679958

carboxypeptidase a

Phaffia rhodozyma CBS 5905

-

-

-

carboxypeptidase C

Saccharomyces cerevisiae

-

-

679852

carboxypeptidase C

Saccharomyces cerevisiae BY4741

-

-

-

carboxypeptidase Y

-

-

-

-

carboxypeptidase Y

Arabidopsis thaliana

-

-

702099

carboxypeptidase Y

Candida albicans

-

-

679926

carboxypeptidase Y

Homo sapiens

P10619

-

702451

carboxypeptidase Y

Saccharomyces cerevisiae

-

-

663479, 665058, 665316, 665563, 677412, 677521, 677947, 678037, 678817, 679755, 679852, 679926, 680178, 680774, 681641, 681642, 681922, 681941, 681977, 682540, 683009, 702764, 731363, 731493

carboxypeptidase Y

Saccharomyces cerevisiae

P00729

-

666040

carboxypeptidase Y

Saccharomyces cerevisiae BJ2168

-

-

-

carboxypeptidase Y

Saccharomyces cerevisiae BY4741

-

-

-

carboxypeptidase Y

Saccharomyces cerevisiae EOS1

-

-

-

carboxypeptidase Y

Schizosaccharomyces pombe

-

-

678820, 704781

CatA

Homo sapiens

-

-

677595, 703982, 732302

CatA

Homo sapiens

P10619

-

732129

CathA

Eriocheir sinensis

-

-

732289

CathA

Homo sapiens

P10619

-

702451

cathepsin A

-

-

-

-

cathepsin A

Eriocheir sinensis

-

-

732289

cathepsin A

Homo sapiens

-

-

664224, 665316, 677595, 703982

cathepsin A

Homo sapiens

P10619

-

702451, 731255, 732129

CPC

Saccharomyces cerevisiae

-

-

679852

CPC

Saccharomyces cerevisiae BY4741

-

-

-

CPY

-

-

-

-

CPY

Arabidopsis thaliana

-

-

702099

CPY

Candida albicans

-

-

679926

CPY

Homo sapiens

P10619

-

702451

CPY

Saccharomyces cerevisiae

-

-

663479, 677521, 678037, 678817, 679755, 679852, 679926, 680774, 681922, 681941, 682540, 682934, 683009, 702764, 731363

CPY

Saccharomyces cerevisiae

P00729

-

700586, 753050

CPY

Saccharomyces cerevisiae BJ2168

-

-

-

CPY

Saccharomyces cerevisiae BY4741

-

-

-

CPY

Schizosaccharomyces pombe

-

-

678820

CTSA

Andrias davidianus

-

-

753993

CTSA

Homo sapiens

P10619

-

732129, 754487

CTSA

Scophthalmus maximus

A0A1X9T5Z1

-

753612

lysosomal carboxypeptidase A

-

-

-

-

lysosomal carboxypeptidase A

Homo sapiens

-

-

677595

lysosomal protective protein

-

-

-

-

lysosomal protective protein

Homo sapiens

P10619

-

702451

Phaseolin

-

-

-

-

Phaseolin

Phaseolus vulgaris

-

-

680306, 680325, 682319, 682394

PpcA

Homo sapiens

P10619

-

704549, 732129

PpcA

Mus musculus

-

-

680391

PpcA

Mus musculus

P16675

-

699085

protective protein/cathepsin A

Homo sapiens

P10619

-

704549

protective protein/cathepsin A

Mus musculus

P16675

-

699085

Scpep1

Mus musculus

-

-

732667

Scpep1

Mus musculus

Q920A5

formerly retinoid-inducible serine carboxypeptidase

708470

serine carboxypeptidase

Mus musculus

-

-

732667

serine carboxypeptidase

Saccharomyces cerevisiae

-

-

679852

serine carboxypeptidase

Saccharomyces cerevisiae BY4741

-

-

-

serine carboxypeptidase

Trypanosoma cruzi

Q6Y3Z8

-

698164

serine carboxypeptidase

Trypanosoma cruzi Y

Q6Y3Z8

-

-

serine carboxypeptidase I

-

-

-

-

serine carboxypeptidase I

Hordeum vulgare

-

-

665030

TcCBP

Trypanosoma cruzi

Q6Y3Z8

-

698164

TcCBP

Trypanosoma cruzi Y

Q6Y3Z8

-

-

additional information

Citrus sp.

-

this enzyme is probably also identical to lysosomal tyrosine carboxypeptidase, formerly EC 3.4.16.3, not a homologue of chymotrypsin or subtilisin, see reference

647222

additional information

Homo sapiens

-

this enzyme is probably also identical to lysosomal tyrosine carboxypeptidase, formerly EC 3.4.16.3, not a homologue of chymotrypsin or subtilisin, see reference

647222

additional information

Saccharomyces cerevisiae

-

this enzyme is probably also identical to lysosomal tyrosine carboxypeptidase, formerly EC 3.4.16.3, not a homologue of chymotrypsin or subtilisin, see reference

647222

additional information

Triticum aestivum

-

this enzyme is probably also identical to lysosomal tyrosine carboxypeptidase, formerly EC 3.4.16.3, not a homologue of chymotrypsin or subtilisin, see reference

647222