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3.4.16.5: carboxypeptidase C

This is an abbreviated version!
For detailed information about carboxypeptidase C, go to the full flat file.

Word Map on EC 3.4.16.5

Reaction

release of a C-terminal amino acid with broad specificity =

Synonyms

A-type metallocarboxypeptidase, acidic serine carboxypeptidase, AtCPY, BRS1, carboxypeptidase a, carboxypeptidase A4, carboxypeptidase C, Carboxypeptidase II, carboxypeptidase Y, carboxypeptidase YSCY, carboxypeptidase-Y, Case, CatA, CathA, cathepsin A, CaY, CP-MI, CP-MIII, CP-WIII, CPA4, CPase, CPC, CPD-Y, CPW, CPY, Cpy1p, CTSA, Cxp1, deamidase, EC 3.4.12.1, EC 3.4.16.1, EC 3.4.16.3, hCath A, HPP, lysosomal carboxypeptidase A, lysosomal protective protein, MO54, More, MpiCP-1, MpiCP-2, Phaseolin, PpcA, PRC1, proCPY, protective protein cathepsin A, protective protein/cathepsin A, retinoid-inducible serine carboxypeptidase, SCP, Scpep1, Ser carboxypeptidase, Ser carboxypeptidase-like protein, serine carboxypeptidase, serine carboxypeptidase 1, serine carboxypeptidase I, serine carboxypeptidase Scpep1, SmSCP-1, TcCBP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.16 Serine-type carboxypeptidases
                3.4.16.5 carboxypeptidase C

KI Value

KI Value on EC 3.4.16.5 - carboxypeptidase C

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
260
acetyl-D-Phe
-
hydrolysis of benzyloxycarbonyl-Phe-Leu
30
acetyl-D-Phe ethyl ester
-
hydrolysis of benzyloxycarbonyl-Phe-Leu
12
acetyl-D-Phe-ethyl ester
-
esterase activity
20 - 25
Acetyl-Phe
1.3 - 1.7
benzyloxycarbonyl-D-Phe
0.2 - 0.3
benzyloxycarbonyl-D-Phe-D-Leu
0.6 - 0.7
benzyloxycarbonyl-Phe
2.6 - 5.7
beta-phenyl-L-lactate
1.9 - 4.5
Beta-phenylpropionate
0.000021
carboxypeptidase Y inhibitor IC
-
pH 4.7, hydrolysis of
-
24
D-Phe
-
hydrolysis of benzyloxycarbonyl-Phe-Leu
5.3 - 11
D-Phe ethyl ester
0.9 - 2.6
Leu-Phe
0.4 - 3.9
Phe
8.3 - 9.1
Phe ethyl ester
3.1 - 8
trans-cinnamate