1.1.1.71: alcohol dehydrogenase [NAD(P)+]

This is an abbreviated version, for detailed information about alcohol dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

a primary alcohol
+
NAD(P)+
=
an aldehyde
+
NAD(P)H
+
H+

Synonyms

ADH, ADH12, ADH2, Adh319, AdhE, aldehyde reductase (NADPH/NADH), DHRS3, HvADH2, HVO_B0071, NAD(P)+-dependent alcohol dehydrogenase, NAD(P)H-dependent aldehyde reductase, NADPH-dependent alcohol dehydrogenase, RADH, retinal reductase, retinal short-chain dehydrogenase/reductase member 3, retinaldehyde reductase, Retinol dehydrogenase, retinol-active alcohol dehydrogenase, retSDR1, TsAdh319, Tsib_0319, VNG_2617G, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.71 alcohol dehydrogenase [NAD(P)+]

KM Value

KM Value on EC 1.1.1.71 - alcohol dehydrogenase [NAD(P)+]

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
13.1
(2S,5S)-2,5-hexanediol
-
60°C, pH 10.5
1.6
(R)-2-hydroxypropiophenone
-
at pH 7.5 and 30°C
244
(RS)-1-phenylethanol
-
with NAD+ as cosubstrate, at pH 6.0 and 70°C
3.6
(S)-2-Hydroxypropiophenone
-
at pH 7.5 and 30°C
6.7
1-butanol
pH 10.0, temperature not specified in the publication
21.4
1-propanol
1.5
2,3-Pentanedione
-
60°C, pH 7.5
4.8
2-Methoxybenzaldehyde
pH 6.5, 30°C
168
2-propanol
24.1
4-methoxybenzaldehyde
pH 6.5, 30°C
1.3 - 9.2
acetaldehyde
30.2
acetoin
-
with NADH as cosubstrate, at pH 6.0 and 70°C
0.08
all-trans-retinal
pH 7.4, 37°C
0.4
all-trans-retinol
pH 7.4, 37°C
15.6
benzaldehyde
-
at pH 7.5 and 30°C
12.3 - 150
benzyl alcohol
52.7 - 78.6
butan-1-ol
0.006 - 3.97
Butanal
5.2
Cyclohexanol
-
at pH 9.0 and 30°C
10.8
cyclohexanone
-
at pH 7.5 and 30°C
54.4
D-xylose
-
60°C, pH 10.5; pH 10.5, 60°C
44 - 4790
ethanol
1.09
heptan-1-ol
-
-
1.22 - 6.8
hexan-1-ol
5.5
Hexanal
pH 6.5, 30°C
61.3
meso-2,3-butanediol
-
with NAD+ as cosubstrate, at pH 6.0 and 70°C
0.0107
methylglyoxal
-
-
0.089 - 1060
NAD+
0.024 - 1200
NADH
0.02 - 1
NADP+
0.00079 - 0.32
NADPH
6.2
octan-1-ol
-
-
5.8 - 14.1
pentan-1-ol
17.75
Pyruvaldehyde
6.9
Salicylaldehyde
pH 6.5, 30°C
27.1
trans-2-hexenal
pH 6.5, 30°C
0.0066
trans-2-nonenal
-
-