1.1.1.71: alcohol dehydrogenase [NAD(P)+]

This is an abbreviated version, for detailed information about alcohol dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

a primary alcohol
+
NAD(P)+
=
an aldehyde
+
NAD(P)H
+
H+

Synonyms

ADH, ADH12, ADH2, Adh319, AdhE, aldehyde reductase (NADPH/NADH), DHRS3, HvADH2, HVO_B0071, NAD(P)+-dependent alcohol dehydrogenase, NAD(P)H-dependent aldehyde reductase, NADPH-dependent alcohol dehydrogenase, RADH, retinal reductase, retinal short-chain dehydrogenase/reductase member 3, retinaldehyde reductase, Retinol dehydrogenase, retinol-active alcohol dehydrogenase, retSDR1, TsAdh319, Tsib_0319, VNG_2617G, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.71 alcohol dehydrogenase [NAD(P)+]

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.71 - alcohol dehydrogenase [NAD(P)+]

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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(RS)-1-phenylethanol + NAD+
1-phenylethanone + NADH + H+
show the reaction diagram
-
100% activity
-
-
?
(RS)-1-phenylethanol + NADP+
1-phenylethanone + NADPH + H+
show the reaction diagram
-
100% activity
-
-
?
1-(2-bromophenyl)ethanol + NAD(P)+
1-(2-bromophenyl)ethanone + NAD(P)H + H+
show the reaction diagram
-
11.3% activity compared to (RS)-1-phenylethanol
-
-
?
1-(2-chlorophenyl)ethanol + NAD(P)+
1-(2-chlorophenyl)ethanone + NAD(P)H + H+
show the reaction diagram
-
16.4% activity compared to (RS)-1-phenylethanol
-
-
?
1-(3-bromophenyl)ethanol + NAD(P)+
1-(3-bromophenyl)ethanone + NAD(P)H + H+
show the reaction diagram
-
315% activity compared to (RS)-1-phenylethanol
-
-
?
1-(3-chlorophenyl)ethanol + NAD(P)+
1-(3-chlorophenyl)ethanone + NAD(P)H + H+
show the reaction diagram
-
205% activity compared to (RS)-1-phenylethanol
-
-
?
1-(4-bromophenyl)ethanol + NAD(P)+
1-(4-bromophenyl)ethanone + NAD(P)H + H+
show the reaction diagram
-
167% activity compared to (RS)-1-phenylethanol
-
-
?
1-(4-chlorophenyl)ethanone + NAD(P)+
1-(4-chlorophenyl)ethanone + NAD(P)H + H+
show the reaction diagram
-
151% activity compared to (RS)-1-phenylethanol
-
-
?
1-(4-fluorophenyl)ethanol + NAD(P)+
1-(4-fluorophenyl)ethanol + NAD(P)H + H+
show the reaction diagram
-
119% activity compared to (RS)-1-phenylethanol
-
-
?
1-(4-methylphenyl)ethanone + NAD(P)+
1-(4-methylphenyl)ethanol + NAD(P)H + H+
show the reaction diagram
-
189% activity compared to (RS)-1-phenylethanol
-
-
?
1-butanol + NAD(P)+
butanal + NAD(P)H + H+
show the reaction diagram
-
2.3% activity compared to (RS)-1-phenylethanol
-
-
?
1-heptanol + NAD(P)+
heptanal + NAD(P)H + H+
show the reaction diagram
-
3.3% activity compared to (RS)-1-phenylethanol
-
-
?
1-hexanol + NAD(P)+
hexanal + NAD(P)H + H+
show the reaction diagram
-
2.8% activity compared to (RS)-1-phenylethanol
-
-
?
1-octanol + NAD(P)+
octanal + NAD(P)H + H+
show the reaction diagram
-
2.3% activity compared to (RS)-1-phenylethanol
-
-
?
1-pentanol + NAD(P)+
pentanal + NAD(P)H + H+
show the reaction diagram
-
2.8% activity compared to (RS)-1-phenylethanol
-
-
?
1-phenyl-1,2-ethanediol + NAD(P)+
?
show the reaction diagram
-
3.4% activity compared to (RS)-1-phenylethanol
-
-
?
1-phenyl-1-propanol + NAD(P)+
1-phenylpropionaldehyde + NAD(P)H + H+
show the reaction diagram
-
13.1% activity compared to (RS)-1-phenylethanol
-
-
?
1-phenyl-2-propanol + NAD(P)+
1-phenylpropan-2-one + NAD(P)H + H+
show the reaction diagram
-
39.1% activity compared to (RS)-1-phenylethanol
-
-
?
1-propanol + NAD(P)+
propionaldehyde + NAD(P)H + H+
show the reaction diagram
-
1.2% activity compared to (RS)-1-phenylethanol
-
-
?
2,2,2-trifluoroacetophenone + NAD(P)H + H+
2,2,2-trifluoro-1-phenylethan-1-ol + NAD(P)+
show the reaction diagram
-
180% activity compared to acetoin
-
-
?
2-bromoacetophenone + NAD(P)H + H+
1-(2-bromophenyl)ethanone + NAD(P)+
show the reaction diagram
-
8.7% activity compared to acetoin
-
-
?
2-butanol + NAD(P)+
butan-2-one + NAD(P)H + H+
show the reaction diagram
-
22.3% activity compared to (RS)-1-phenylethanol
-
-
?
2-chloro-1-phenylethanol + NAD(P)+
2-chloro-1-phenylethan-1-one + NAD(P)H + H+
show the reaction diagram
-
0.3% activity compared to (RS)-1-phenylethanol
-
-
?
2-heptanol + NAD(P)+
heptan-2-one + NAD(P)H + H+
show the reaction diagram
-
61.6% activity compared to (RS)-1-phenylethanol
-
-
?
2-hexanol + NAD(P)+
hexan-2-one + NAD(P)H + H+
show the reaction diagram
-
38.7% activity compared to (RS)-1-phenylethanol
-
-
?
2-hexanone + NAD(P)H + H+
hexan-2-ol + NAD(P)+
show the reaction diagram
-
3.6% activity compared to acetoin
-
-
?
2-octanol + NAD(P)+
octan-2-one + NAD(P)H + H+
show the reaction diagram
-
45.8% activity compared to (RS)-1-phenylethanol
-
-
?
2-pentanol + NAD(P)+
pentan-2-one + NAD(P)H + H+
show the reaction diagram
-
30.2% activity compared to (RS)-1-phenylethanol
-
-
?
2-phenylethanol + NAD(P)+
phenylacetaldehyde + NAD(P)H + H+
show the reaction diagram
-
0.3% activity compared to (RS)-1-phenylethanol
-
-
?
2-propanol + NAD(P)+
propan-2-one + NAD(P)H + H+
show the reaction diagram
-
5.3% activity compared to (RS)-1-phenylethanol
-
-
?
acetoin + NAD(P)+
2,3-butanedil + NAD(P)H + H+
show the reaction diagram
-
4.5% activity compared to (RS)-1-phenylethanol
-
-
?
acetoin + NAD(P)H + H+
butan-2,3-dione + NAD(P)H + H+
show the reaction diagram
-
100% activity
-
-
?
acetone + NAD(P)H + H+
propan-2-ol + NAD(P)+
show the reaction diagram
-
4.1% activity compared to acetoin
-
-
?
all-trans-retinal + NADPH + H+
all-trans-retinol + NADP+
show the reaction diagram
-
-
-
-
?
cyclohexanol + NAD(P)+
cyclohexanone + NAD(P)H + H+
show the reaction diagram
-
52.3% activity compared to (RS)-1-phenylethanol
-
-
?
cyclohexanone + NAD(P)H + H+
cyclohexanol + NAD(P)+
show the reaction diagram
-
19.1% activity compared to acetoin
-
-
?
D-arabinose + NAD(P)+
?
show the reaction diagram
-
21.4% activity compared to (RS)-1-phenylethanol
-
-
?
dihydroxyacetone + NAD(P)H + H+
?
show the reaction diagram
-
34.8% activity compared to acetoin
-
-
?
ethanol + NAD(P)+
acetaldehyde + NAD(P)H + H+
show the reaction diagram
-
0.5% activity compared to (RS)-1-phenylethanol
-
-
?
ethyl pyruvate + NAD(P)H + H+
?
show the reaction diagram
-
294% activity compared to acetoin
-
-
?
hexanal + NAD(P)H + H+
hexan-1-ol + NAD(P)+
show the reaction diagram
-
12.9% activity compared to acetoin
-
-
?
L-arabinose + NAD(P)+
?
show the reaction diagram
-
5.2% activity compared to (RS)-1-phenylethanol
-
-
?
meso-2,3-butanediol + NAD+
?
show the reaction diagram
-
272% activity compared to (RS)-1-phenylethanol
-
-
?
meso-2,3-butanediol + NADP+
?
show the reaction diagram
-
272% activity compared to (RS)-1-phenylethanol
-
-
?
methanol + NAD(P)+
formaldehyde + NAD(P)H + H+
show the reaction diagram
-
0.2% activity compared to (RS)-1-phenylethanol
-
-
?
methyl benzoylformate + NAD(P)H + H+
?
show the reaction diagram
-
67% activity compared to acetoin
-
-
?
phenylacetaldehyde + NAD(P)H + H+
2-phenylethan-1-ol + NAD(P)+
show the reaction diagram
-
18.6% activity compared to acetoin
-
-
?
pyruvic aldehyde + NAD(P)H + H+
?
show the reaction diagram
-
328% activity compared to acetoin
-
-
?
retinaldehyde + NADH
retinol + NAD+
show the reaction diagram
-
the enzyme is involved in retinol and vitamin A metabolism, retinoic acid is important in intestinal epithelial cell proliferation and differentiation, the enzyme also plays a role in dietary conversion of beta-carotene to retinol via retinaldehyde
-
-
r
additional information
?
-