1.1.1.71: alcohol dehydrogenase [NAD(P)+]

This is an abbreviated version, for detailed information about alcohol dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

a primary alcohol
+
NAD(P)+
=
an aldehyde
+
NAD(P)H
+
H+

Synonyms

ADH, ADH12, ADH2, Adh319, AdhE, aldehyde reductase (NADPH/NADH), DHRS3, HvADH2, HVO_B0071, NAD(P)+-dependent alcohol dehydrogenase, NAD(P)H-dependent aldehyde reductase, NADPH-dependent alcohol dehydrogenase, RADH, retinal reductase, retinal short-chain dehydrogenase/reductase member 3, retinaldehyde reductase, Retinol dehydrogenase, retinol-active alcohol dehydrogenase, retSDR1, TsAdh319, Tsib_0319, VNG_2617G, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.71 alcohol dehydrogenase [NAD(P)+]

Specific Activity

Specific Activity on EC 1.1.1.71 - alcohol dehydrogenase [NAD(P)+]

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.01
-
with acetone, at pH 7.5 and 30C
0.025
-
wild-type, cofoactor NADPH, pH 7.6, 55C
0.05
-
with acetaldehyde, at pH 7.5 and 30C
0.052
-
mutant P704L/H734R, cofoactor NADH, pH 7.6, 55C
0.08
-
with 2,5-hexandione, at pH 7.5 and 30C
0.11
-
with cyclohexanone, at pH 7.5 and 30C
0.12
-
mutant P704L/H734R, cofoactor NADPH, pH 7.6, 55C
0.56
-
with 4-phenyl-2-butanone, at pH 7.5 and 30C
2.7
-
wild-type, cofoactor NADH, pH 7.6, 55C
4.35
-
with acetophenone, at pH 7.5 and 30C
4.89
-
with benzaldehyde, at pH 7.5 and 30C
8.36
-
with cyclohexanol, at pH 10.5 and 30C
9.78
-
with cyclohexanone, at pH 7.5 and 30C
11.58
-
with 3-methylcyclohexanol, at pH 10.5 and 30C
11.7
-
with 3-fluorobenzaldehyde, at pH 7.5 and 30C
12.62
-
with 3-methylcyclohexanone, at pH 7.5 and 30C
17.1
-
with (S)-2-hydroxypropiophenone, at pH 7.5 and 30C
18.83
-
with cyclohexenol, at pH 10.5 and 30C
23.31
-
2-bromobenzaldehyde, at pH 7.5 and 30C
362.6
-
with (R)-2-hydroxypropiophenone, at pH 7.5 and 30C