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Literature summary for 1.1.1.71 extracted from

  • Brophy, P.M.; Crowley, P.; Barrett, J.
    A novel NADPH/NADH-dependent aldehyde reduction enzyme isolated from the tapeworm Moniezia expansa (1990), FEBS Lett., 263, 305-307.
    View publication on PubMed
Search for more literature for 1.1.1.71

Inhibitors

Inhibitors Comment Organism Structure
Phenobarbital 0.5 mM, 30% inhibition Moniezia expansa
pyrazole 0.5 mM, 35% inhibition Moniezia expansa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0066
-
 trans-2-nonenal
-
 Moniezia expansa
0.0107
-
 methylglyoxal
-
 Moniezia expansa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Moniezia expansa 5829
-

Organism

Organism UniProt Comment Textmining
Moniezia expansa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
chromatofocusing, reactive red Moniezia expansa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ethanediol + NADP+
-
 Moniezia expansa glyoxal + NADPH
-
 ?
ethanol + NADP+ oxidation rate at 5% of reduction rate Moniezia expansa ethanal + NADPH + H+
-
 r
hexan-1-ol + NADP+
-
 Moniezia expansa hexanal + NADPH
-
 ?
methylglyoxal + NADPH + H+
-
 Moniezia expansa 2-hydroxy-propanal + NADP+
-
 ?
propan-1-ol + NADP+ oxidation rate at 5% of reduction rate Moniezia expansa propanal + NADPH
-
 r
trans-2-nonenal + NADPH + H+
-
 Moniezia expansa trans-2-nonen-1-ol + NADP+
-
 ?
trans-2-octenal + NADPH + H+
-
 Moniezia expansa trans-2-octen-1-ol + NADP+
-
 ?
trans-trans-2,4-decadienal + NADPH + H+
-
 Moniezia expansa trans-trans-2,4-decadienol + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD(P)H 50% of NADPH reduction rate with NADH Moniezia expansa