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Information on EC 1.1.99.18 - cellobiose dehydrogenase (acceptor)

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IUBMB Comments
Also acts, more slowly, on cello-oligosaccharides, lactose and D-glucosyl-1,4-beta-D-mannose. The enzyme from the white rot fungus Phanerochaete chrysosporium is unusual in having two redoxin domains, one containing a flavin and the other a protoheme group. It transfers reducing equivalents from cellobiose to two types of redox acceptor: two-electron oxidants, including redox dyes, benzoquinones, and molecular oxygen, and one-electron oxidants, including semiquinone species, iron(II) complexes, and the model acceptor cytochrome c . 2,6-Dichloroindophenol can act as acceptor in vitro.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
cellobiose dehydrogenase, cdh-1, mtcdh, cellobiose:quinone oxidoreductase, cdh iib, cdh iia, cellobiose oxidoreductase, cellobiose-quinone oxidoreductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor
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PATHWAY SOURCE
PATHWAYS