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Literature summary for 1.1.99.18 extracted from

  • Tangthirasunun, N.; Navarro, D.; Garajova, S.; Chevret, D.; Tong, L.; Gautier, V.; Hyde, K.; Silar, P.; Berrin, J.
    Inactivation of cellobiose dehydrogenases modifies the cellulose degradation mechanism of Podospora anserina (2017), Appl. Environ. Microbiol., 83, e02716-16 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Podospora anserina
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-
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Synonyms

Synonyms Comment Organism
CDH1
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 Podospora anserina
Cdh2
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 Podospora anserina

General Information

General Information Comment Organism
malfunction the three CDH genes of Podospora anserina are inactivated, resulting in single and multiple CDH mutants. Almost no difference is detected in growth and fertility of the mutants on various lignocellulose sources, except on crystalline cellulose, on which a 2fold decrease in fertility of the mutants lacking Podospora anserina CDH1 (PaCDH1) and PaCDH2 is observed. A striking difference between wild-type and mutant secretomes is observed. The secretome of the mutant lacking all CDHs contains five beta-glucosidases, whereas the wild type had only one. Podospora anserina seems to compensate for the lack of CDH with secretion of beta-glucosidases Podospora anserina
metabolism the enzyme enables Podospora anserina to consume crystalline cellulose. It seems to play a minor role on actual substrates Podospora anserina