Reference on EC 3.1.1.4 - phospholipase A2 and Organism(s) Homo sapiens and UniProt Accession O60733
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dessen, A.; Tang, J.; Schmidt, H.; Stahl, M.; Clark, J.D.; Seehra, J.; Somers, W.S.
Crystal structure of human cytosolic Phospholipase A2 reveals a novel topology and catalytic mechanism
Cell
97
349-360
1999
Homo sapiens
Larsson Forsell, P.K.A.; Kennedy, B.P.; Claesson, H.E.
The human calcium-independent phospholipase A2 gene
Eur. J. Biochem.
262
575-585
1999
Rattus norvegicus, Homo sapiens (O60733), Homo sapiens
Rice, S.Q.J.; Southan, C.; Boyd, H.F.; Terrett, J.A.; MacPhee, C.H.; Moores, K.; Gloger, I.S.; Tew, D.G.
Expression, purification and characterization of a human serine-dependent phospholipase A2 with high specificity for oxidized phospholipids and platelet activating factor
Biochem. J.
330
1309-1315
1998
Homo sapiens
-
Han, S.K.; Yoon, E.T.; Cho, W.
Bacterial expression and characterization of human secretory class V phospholipase A2
Biochem. J.
331
353-357
1998
Homo sapiens
-
Chen, D.; Dennis, E.A.
Expression and characterization of human group V phospholipase A2
Biochim. Biophys. Acta
1394
57-64
1998
Homo sapiens, Mus musculus, Rattus norvegicus
Akiba, S.; Dodia, C.; Chen, X.; Fisher, A.B.
Characterization of acidic Ca2+-independent phospholipase A2 of bovine lung
Comp. Biochem. Physiol. B
120
393-404
1998
Bos taurus, Homo sapiens
Lamura, E.; Hillier, K.; Kinkaid, A.; Wilton, D.
Compartmentalisation and characteristics of a Ca2+-dependent phospholipase A2 in human colon mucosa
Biochem. Pharmacol.
53
1323-1332
1997
Homo sapiens
Han, S.K.; Lee, B.I.; Cho, W.
Bacterial expression and characterisation of human pancreatic phospholipase A2
Biochim. Biophys. Acta
1346
185-192
1997
Homo sapiens
Yang, H.C.; Farooqui, A.A.; Horrocks, L.A.
Characterization of plasmalogen-selective phospholipase A2 from bovine brain
Adv. Exp. Med. Biol.
416
309-313
1996
Bos taurus, Homo sapiens
Kawauchi, Y.; Takasaki, J.; Matsuura, Y.; Masuho, Y.
Preparation and characterization of human rheumatoid arthritic synovial fluid phospholipase A2 produced by recombinant baculovirus-infected cells
J. Biochem.
116
82-87
1994
Homo sapiens
-
Minami, T.; Tojo, H.; Shinomura, Y.; Matsuzawa, Y.; Okamoto, M.
Purification and characterization of a phospholipase A2 from human ileal mucosa
Biochim. Biophys. Acta
1170
125-130
1993
Homo sapiens
Rehfeldt, W.; Resch, K.; Goppelt-Struebe, M.
Cytosolic phospholipase A2 from human monocytic cells: characterization of substrate specificity and Ca2+-dependent membrane association
Biochem. J.
293
255-261
1993
Homo sapiens
Hoffmann, G.E.; Schneider, E.; Brand, K.; Kozumplik, V.; Fateh-Moghadam, S.
Characterization of a phospholipase A2 in human serum
Eur. J. Clin. Chem. Clin. Biochem.
30
111-117
1992
Homo sapiens
Franken, P.A.; van den Berg, L.; Huang, J.; Gunyuzlu, P.; Lugtigheid, R.B.; Verheij, H.M.; de Haas, G.H.
Purification and characterization of a mutant human platelet phospholipase A2 expressed in Escherichia coli
Eur. J. Biochem.
203
89-98
1992
Homo sapiens, Naja melanoleuca, Sus scrofa
Takayama, K.; Kudo, I.; Kim, D.K.; Nagata, K.; Nozawa, Y.; Inoue, K.
Purification and characterization of human platelet phospholipase A2 which preferentially hydrolyzes an arachidonoyl residue
FEBS Lett.
282
326-330
1991
Homo sapiens
Donne-Op den Kelder, G.M.; de Haas, G.H.; Egmond, M.R.
Localization of the second calcium ion binding site in porcine and equine phospholipase A2
Biochemistry
22
2470-2478
1983
Bos taurus, Equus caballus, Homo sapiens, Sus scrofa
Sahu, S.; Lynn, W.S.
Characterization of phospholipase A from pulmonary secretions of patients with alveolar proteinosis
Biochim. Biophys. Acta
489
307-317
1977
Homo sapiens
Perisic, O.; Fong, S.; Lynch, D.E.; Bycroft, M.; Williams, R.L.
Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2
J. Biol. Chem.
273
1596-1604
1998
Homo sapiens
Edwards, S.H.; Thompson, D.; Baker, S.F.; Wood, S.P.; Wilton, D.C.
The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism
Biochemistry
41
15468-15476
2002
Homo sapiens (P14555), Homo sapiens
Winstead, M.V.; Balsinde, J.; Dennis, E.A.
Calcium-independent phospholipase A2: structure and function
Biochim. Biophys. Acta
1488
28-39
2000
Homo sapiens, Mammalia, Mus musculus, Rattus norvegicus
Shin, H.S.; Chin, M.R.; Kim, J.S.; Chung, J.H.; Ryu, C.K.; Jung, S.Y.; Kim, D.K.
Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells
J. Biol. Chem.
277
21086-21094
2002
Bos taurus, Homo sapiens
Stewart, A.; Ghosh, M.; Spencer, D.M.; Leslie, C.C.
Enzymatic properties of human cytosolic phospholipase A2g
J. Biol. Chem.
277
29526-29536
2002
Homo sapiens
Farooqui, A.A.; Ong, W.Y.; Horrocks, L.A.; Farooqui, T.
Brain cytosolic phospholipase A2: localization, role, and involvement in neurological diseases
Neuroscientist
6
169-180
2000
Bos taurus, Homo sapiens, Mammalia, Rattus norvegicus
-
Rose, T.M.; Prestwich, G.D.
Fluorogenic phospholipids as head group-selective reporters of phospholipase A activity
ACS Chem. Biol.
1
83-92
2006
Streptomyces violaceoruber, Apis mellifera, Bos taurus, Homo sapiens, Naja mossambica
Qin, S.; Pande, A.H.; Nemec, K.N.; Tatulian, S.A.
The N-terminal alpha-helix of pancreatic phospholipase A2 determines productive-mode orientation of the enzyme at the membrane surface
J. Mol. Biol.
344
71-89
2004
Homo sapiens
Pande, A.H.; Qin, S.; Nemec, K.N.; He, X.; Tatulian, S.A.
Isoform-specific membrane insertion of secretory phospholipase A2 and functional implications
Biochemistry
45
12436-12447
2006
Apis mellifera (P00630), Apis mellifera, Homo sapiens (P14555), Homo sapiens
Nemec, K.N.; Pande, A.H.; Qin, S.; Bieber Urbauer, R.J.; Tan, S.; Moe, D.; Tatulian, S.A.
Structural and functional effects of tryptophans inserted into the membrane-binding and substrate-binding sites of human group IIA phospholipase A2
Biochemistry
45
12448-12460
2006
Homo sapiens
Gora, S.; Lambeau, G.; Bollinger, J.G.; Gelb, M.; Ninio, E.; Karabina, S.
The proinflammatory mediator Platelet Activating Factor is an effective substrate for human group X secreted phospholipase A2
Biochim. Biophys. Acta
1761
1093-1099
2006
Homo sapiens
Hess, M.; Schulze Elfringhoff, A.; Lehr, M.
1-(5-Carboxy- and 5-carbamoylindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: bioisosteric replacement of the carboxylic acid and carboxamide moiety
Bioorg. Med. Chem.
15
2883-2891
2007
Homo sapiens
Moon, T.C.; Quan, Z.; Kim, J.; Kim, H.P.; Kudo, I.; Murakami, M.; Park, H.; Chang, H.W.
Inhibitory effect of synthetic C-C biflavones on various phospholipase A2s activity
Bioorg. Med. Chem.
15
7138-7143
2007
Homo sapiens, Homo sapiens (P47712)
Davis, B.; Koster, G.; Douet, L.J.; Scigelova, M.; Woffendin, G.; Ward, J.M.; Smith, A.; Humphres, J.; Burnand, K.G.; Macphee, C.H.; Postle, A.D.
Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein
J. Biol. Chem.
283
6428-6437
2007
Homo sapiens
Touaibia, M.; Djimde, A.; Cao, F.; Boilard, E.; Bezzine, S.; Lambeau, G.; Redeuilh, C.; Lamouri, A.; Massicot, F.; Chau, F.; Dong, C.Z.; Heymans, F.
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities
J. Med. Chem.
50
1618-1626
2007
Homo sapiens, Sus scrofa
Kim, J.O.; Chakrabarti, B.K.; Guha-Niyogi, A.; Louder, M.K.; Mascola, J.R.; Ganesh, L.; Nabel, G.J.
Lysis of human immunodeficiency virus type 1 by a specific secreted human phospholipase A2
J. Virol.
81
1444-1450
2007
Homo sapiens
Zhang, F.; Wang, Y.
Cloning, expression, and purification of lipoprotein-associated phospholipase A2 in Pichia pastoris
Mol. Biotechnol.
33
29-36
2006
Homo sapiens (Q13093)
Ho, T.C.; Chen, S.L.; Yang, Y.C.; Lo, T.H.; Hsieh, J.W.; Cheng, H.C.; Tsao, Y.P.
Cytosolic phospholipase A2-alpha is an early apoptotic activator in PEDF-induced endothelial cell apoptosis
Am. J. Physiol. Cell Physiol.
296
C273-C284
2009
Homo sapiens
Wu, Y.; Feinstein, S.I.; Manevich, Y.; Chowdhury, I.; Pak, J.H.; Kazi, A.; Dodia, C.; Speicher, D.W.; Fisher, A.B.
Mitrogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A2 activity
Biochem. J.
419
669-679
2009
Homo sapiens, Rattus norvegicus
Antonopoulou, G.; Barbayianni, E.; Magrioti, V.; Cotton, N.; Stephens, D.; Constantinou-Kokotou, V.; Dennis, E.A.; Kokotos, G.
Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A2 enzymes
Bioorg. Med. Chem.
16
10257-10269
2008
Homo sapiens
Fritsche, A.; Elfringhoff, A.S.; Fabian, J.; Lehr, M.
1-(2-Carboxyindol-5-yloxy)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: synthesis, biological activity, metabolic stability, and solubility
Bioorg. Med. Chem.
16
3489-3500
2008
Homo sapiens
Simonsen, A.C.
Activation of phospholipase A2 by ternary model membranes
Biophys. J.
94
3966-3975
2008
Homo sapiens
Kim, C.; Kim, J.Y.; Kim, J.H.
Cytosolic phospholipase A2, lipoxygenase metabolites, and reactive oxygen species
BMB Rep.
41
555-559
2008
Homo sapiens
Burke, J.E.; Dennis, E.A.
Phospholipase A2 biochemistry
Cardiovasc. Drugs Ther.
23
49-59
2009
Apis mellifera, Bitis gabonica, Bos taurus, Crotalus sp., Homo sapiens, Mus musculus, Naja naja, Oryza sativa, Rattus norvegicus, Sus scrofa, Protoparvovirus
Monti, M.C.; Casapullo, A.; Cavasotto, C.N.; Tosco, A.; Dal Piaz, F.; Ziemys, A.; Margarucci, L.; Riccio, R.
The binding mode of petrosaspongiolide M to the human group IIA phospholipase A2: exploring the role of covalent and noncovalent interactions in the inhibition process
Chemistry
15
1155-1163
2009
Homo sapiens (P14555), Homo sapiens
De Luca, D.; Minucci, A.; Zecca, E.; Piastra, M.; Pietrini, D.; Carnielli, V.P.; Zuppi, C.; Tridente, A.; Conti, G.; Capoluongo, E.D.
Bile acids cause secretory phospholipase A2 activity enhancement, revertible by exogenous surfactant administration
Intensive Care Med.
35
321-326
2009
Homo sapiens
Burke, J.E.; Hsu, Y.H.; Deems, R.A.; Li, S.; Woods, V.L.; Dennis, E.A.
A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2
J. Biol. Chem.
283
31227-31236
2008
Homo sapiens (P47712)
Tian, W.; Wijewickrama, G.T.; Kim, J.H.; Das, S.; Tun, M.P.; Gokhale, N.; Jung, J.W.; Kim, K.P.; Cho, W.
Mechanism of regulation of group IVA phospholipase A2 activity by Ser727 phosphorylation
J. Biol. Chem.
283
3960-3971
2008
Homo sapiens
Tucker, D.E.; Ghosh, M.; Ghomashchi, F.; Loper, R.; Suram, S.; St John, B.; Girotti, M.; Bollinger, J.G.; Gelb, M.H.; Leslie, C.C.
Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function
J. Biol. Chem.
284
9596-9611
2009
Homo sapiens
Hess, M.; Schulze Elfringhoff, A.; Lehr, M.
Design and synthesis of 3-pyrrol-3-yl-3H-isobenzofuran-1-ones as inhibitors of human cytosolic phospholipase A2alpha
J. Enzyme Inhib. Med. Chem.
23
946-957
2008
Homo sapiens
Oslund, R.C.; Cermak, N.; Gelb, M.H.
Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2
J. Med. Chem.
51
4708-4714
2008
Homo sapiens, Mus musculus
Baskakis, C.; Magrioti, V.; Cotton, N.; Stephens, D.; Constantinou-Kokotou, V.; Dennis, E.A.; Kokotos, G.
Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes
J. Med. Chem.
51
8027-8037
2008
Homo sapiens
Souza, A.D.; Rodrigues-Filho, E.; Souza, A.Q.; Pereira, J.O.; Calgarotto, A.K.; Maso, V.; Marangoni, S.; Da Silva, S.L.
Koninginins, phospholipase A2 inhibitors from endophytic fungus Trichoderma koningii
Toxicon
51
240-250
2008
Homo sapiens, Bothrops jararacussu
Methot, M.; Demers, E.; Bussieres, S.; Desbat, B.; Breton, R.; Salesse, C.
Phospholipid monolayer hydrolysis by cytosolic phospholipase A2 gamma and lecithin retinol acyl transferase
Colloids Surf. A Physicochem. Eng. Asp.
321
147-150
2008
Homo sapiens
-
Judson, B.L.; Brown, W.J.
Assembly of an intact Golgi complex requires phospholipase A2 (PLA2) activity, membrane tubules, and dynein-mediated microtubule transport
Biochem. Biophys. Res. Commun.
389
473-477
2009
Homo sapiens
Giannattasio, G.; Lai, Y.; Granata, F.; Mounier, C.M.; Nallan, L.; Oslund, R.; Leslie, C.C.; Marone, G.; Lambeau, G.; Gelb, M.H.; Triggiani, M.
Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis
Biochim. Biophys. Acta
1791
92-102
2009
Homo sapiens (O15496), Homo sapiens
Bovens, S.; Kaptur, M.; Elfringhoff, A.S.; Lehr, M.
1-(5-Carboxyindol-1-yl)propan-2-ones as inhibitors of human cytosolic phospholipase A2alpha: synthesis and properties of bioisosteric benzimidazole, benzotriazole and indazole analogues
Bioorg. Med. Chem. Lett.
19
2107-2111
2009
Homo sapiens
Boukli, L.; Touaibia, M.; Meddad-Belhabich, N.; Djimde, A.; Park, C.; Kim, J.; Yoon, J.; Lamouri, A.; Heymans, F.
Design of new potent and selective secretory phospholipase A2 inhibitors. Part 5: Synthesis and biological activity of 1-alkyl-4-[4,5-dihydro-1,2,4-[4H]-oxadiazol-5-one-3-ylmethylbenz-4'-yl(oyl)] piperazines
Bioorg. Med. Chem.
16
1242-1253
2008
Homo sapiens, Sus scrofa
Barbayianni, E.; Stephens, D.; Grkovich, A.; Magrioti, V.; Hsu, Y.H.; Dolatzas, P.; Kalogiannidis, D.; Dennis, E.A.; Kokotos, G.
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides
Bioorg. Med. Chem.
17
4833-4843
2009
Homo sapiens
Wang, W.Y.; Li, J.; Yang, D.; Xu, W.; Zha, R.P.; Wang, Y.P.
OxLDL stimulates lipoprotein-associated phospholipase A2 expression in THP-1 monocytes via PI3K and p38 MAPK pathways
Cardiovasc. Res.
85
845-852
2010
Homo sapiens
Chalbot, S.; Zetterberg, H.; Blennow, K.; Fladby, T.; Grundke-Iqbal, I.; Iqbal, K.
Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease
Clin. Chem.
55
2171-2179
2009
Homo sapiens, Mus musculus
Garcia-Garcia, H.M.; Serruys, P.W.
Phospholipase A2 inhibitors
Curr. Opin. Lipidol.
20
327-332
2009
Homo sapiens, Sus scrofa
Dharmappa, K.K.; Mohamed, R.; Shivaprasad, H.V.; Vishwanath, B.S.
Genistein, a potent inhibitor of secretory phospholipase A2: a new insight in down regulation of inflammation
Inflammopharmacology
18
25-31
2010
Homo sapiens
Gubern, A.; Casas, J.; Barcelo-Torns, M.; Barneda, D.; de la Rosa, X.; Masgrau, R.; Picatoste, F.; Balsinde, J.; Balboa, M.A.; Claro, E.
Group IVA phospholipase A2 is necessary for the biogenesis of lipid droplets
J. Biol. Chem.
283
27369-27382
2008
Homo sapiens
Lee, C.W.; Lee, I.T.; Lin, C.C.; Lee, H.C.; Lin, W.N.; Yang, C.M.
Activation and induction of cytosolic phospholipase A2 by IL-1beta in human tracheal smooth muscle cells: role of MAPKs/p300 and NF-kappaB
J. Cell. Biochem.
109
1045-1056
2010
Homo sapiens
Mouchlis, V.D.; Mavromoustakos, T.M.; Kokotos, G.
Design of new secreted phospholipase A2 inhibitors based on docking calculations by modifying the pharmacophore segments of the FPL67047XX inhibitor
J. Comput. Aided Mol. Des.
24
107-115
2010
Homo sapiens (P14555)
Casas, J.; Meana, C.; Esquinas, E.; Valdearcos, M.; Pindado, J.; Balsinde, J.; Balboa, M.A.
Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages
J. Immunol.
183
2767-2774
2009
Homo sapiens
Ayilavarapu, S.; Kantarci, A.; Fredman, G.; Turkoglu, O.; Omori, K.; Liu, H.; Iwata, T.; Yagi, M.; Hasturk, H.; Van Dyke, T.E.
Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils
J. Immunol.
184
1507-1515
2010
Homo sapiens
Meliton, A.Y.; Munoz, N.M.; Meliton, L.N.; Binder, D.C.; Osan, C.M.; Zhu, X.; Dudek, S.M.; Leff, A.R.
Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro
J. Inflamm.
7
14
2010
Homo sapiens
Burke, J.; Dennis, E.
Phospholipase A2 structure/function, mechanism, and signaling
J. Lipid Res.
50 Suppl
S237-S242
2009
Apis mellifera, Homo sapiens, Mus musculus, Naja naja
Dreiseitel, A.; Korte, G.; Schreier, P.; Oehme, A.; Locher, S.; Hajak, G.; Sand, P.G.
sPhospholipase A(2) is inhibited by anthocyanidins
J. Neural Transm.
116
1071-1077
2009
Homo sapiens
Korotaeva, A.A.; Samoilova, E.V.; Piksina, G.F.; Prokazova, N.V.
Oxidized phosphatidylcholine stimulates activity of secretory phospholipase A2 group IIA and abolishes sphingomyelin-induced inhibition of the enzyme
Prostaglandins Other Lipid Mediat.
91
38-41
2010
Homo sapiens
Fonseca, R.G.; Ferreira, T.L.; Ward, R.J.
Refolding and purification of the human secreted group IID phospholipase A2 expressed as inclusion bodies in Escherichia coli
Protein Expr. Purif.
67
82-87
2009
Homo sapiens
Nevalainen, T.J.
1-Cysteine peroxiredoxin: A dual-function enzyme with peroxidase and acidic Ca2+-independent phospholipase A2 activities
Biochimie
92
638-644
2010
Homo sapiens
Ghomashchi, F.; Naika, G.S.; Bollinger, J.G.; Aloulou, A.; Lehr, M.; Leslie, C.C.; Gelb, M.H.
Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms
J. Biol. Chem.
285
36100-36111
2010
Homo sapiens, Mus musculus
Madsen, J.J.; Linderoth, L.; Subramanian, A.K.; Andresen, T.L.; Peters, G.H.
Secretory phospholipase A2 activity toward diverse substrates
J. Phys. Chem. B
115
6853-6861
2011
Agkistrodon piscivorus piscivorus, Apis mellifera (P00630), Homo sapiens (P14555)
Schmidt, J.A.; Kalkofen, D.N.; Donovan, K.W.; Brown, W.J.
A role for phospholipase A2 activity in membrane tubule formation and TGN trafficking
Traffic
11
1530-1536
2010
Homo sapiens
Qiu, S.; Lai, L.
Tailoring the pH dependence of human non-pancreatic secretory phospholipase A2 by engineering surface charges
Appl. Biochem. Biotechnol.
171
1454-1464
2013
Homo sapiens
Aragao, E.A.; Vieira, D.S.; Chioato, L.; Ferreira, T.L.; Lourenzoni, M.R.; Silva, S.R.; Ward, R.J.
Characterization of suramin binding sites on the human group IIA secreted phospholipase A2 by site-directed mutagenesis and molecular dynamics simulation
Arch. Biochem. Biophys.
519
17-22
2012
Homo sapiens (P14555)
Fonseca-Maldonado, R.; Ferreira, T.L.; Ward, R.J.
The bactericidal effect of human secreted group IID phospholipase A2 results from both hydrolytic and non-hydrolytic activities
Biochimie
94
1437-1440
2012
Homo sapiens (Q9UNK4), Homo sapiens
Hiraoka, M.; Okamoto, K.; Ohguro, H.; Abe, A.
Role of N-glycosylation of human lysosomal phospholipase A2 for the formation of catalytically active enzyme
J. Lipid Res.
54
3098-3105
2013
Homo sapiens (Q8NCC3), Homo sapiens
Xu, S.; Pei, R.; Guo, M.; Han, Q.; Lai, J.; Wang, Y.; Wu, C.; Zhou, Y.; Lu, M.; Chen, X.
Cytosolic phospholipase A2 gamma is involved in hepatitis C virus replication and assembly
J. Virol.
86
13025-13037
2012
Homo sapiens
Duvernay, M.T.; Matafonov, A.; Lindsley, C.W.; Hamm, H.E.
Platelet lipidomic profiling novel insight into cytosolic phospholipase A2alpha activity and its role in human platelet activation
Biochemistry
54
5578-5588
2015
Homo sapiens (P47712), Homo sapiens (W0FXB0)
Batchu, K.C.; Haenninen, S.; Jha, S.K.; Jeltsch, M.; Somerharju, P.
Factors regulating the substrate specificity of cytosolic phospholipase A2-alpha in vitro
Biochim. Biophys. Acta
1861
1597-1604
2016
Homo sapiens (P47712), Homo sapiens
Arnsmann, M.; Hanekamp, W.; Elfringhoff, A.S.; Lehr, M.
Structure-activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A2. Effect of substituents at the indole 3-position on activity, solubility, and metabolic stability
Eur. J. Med. Chem.
125
1107-1114
2017
Homo sapiens (P47712)
Fisher, A.B.
The phospholipase A2 activity of peroxiredoxin 6
J. Lipid Res.
59
1132-1147
2018
Trematomus bernacchii, Xenopus tropicalis (B1WAZ6), Mus musculus (O08709), Rattus norvegicus (O35244), Bos taurus (O77834), Homo sapiens (P30041), Gallus gallus (Q5ZJF4), Arabidopsis thaliana (Q8S8N6)
Wang, H.; Klein, M.G.; Snell, G.; Lane, W.; Zou, H.; Levin, I.; Li, K.; Sang, B.C.
Structure of human GIVD cytosolic phospholipase A2 reveals insights into substrate recognition
J. Mol. Biol.
428
2769-2779
2016
Homo sapiens (Q86XP0), Homo sapiens
Movahedi Naini, S.; Sheridan, A.M.; Force, T.; Shah, J.V.; Bonventre, J.V.
Group IVA cytosolic phospholipase A2 regulates the G2-to-M transition by modulating the activity of tumor suppressor SIRT2
Mol. Cell. Biol.
35
3768-3784
2015
Homo sapiens (P47712)
Mouchlis, V.D.; Bucher, D.; McCammon, J.A.; Dennis, E.A.
Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates
Proc. Natl. Acad. Sci. USA
112
E516-E525
2015
Homo sapiens (O60733), Homo sapiens (P47712), Homo sapiens
