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Literature summary for 3.1.1.4 extracted from

  • Simonsen, A.C.
    Activation of phospholipase A2 by ternary model membranes (2008), Biophys. J., 94, 3966-3975.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information activation of phospholipase A2 by ternary model membranes, mechanism, overview Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of type IIa human PLA2 in mice correlating with elevated atherosclerotic lesions, membranes with elevated cholesterol content can be generated by PLA2 activation, mechanism, overview Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1,2-dioleoyl-sn-glycero-3-phosphocholine + H2O Homo sapiens
-
1-oleoylglycerophosphocholine + oleic acid
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O Homo sapiens
-
1-palmitoylglycerophosphocholine + palmitic acid
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O Homo sapiens
-
?
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dioleoyl-sn-glycero-3-phosphocholine + H2O
-
Homo sapiens 1-oleoylglycerophosphocholine + oleic acid
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
Homo sapiens 1-palmitoylglycerophosphocholine + palmitic acid
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O
-
Homo sapiens ?
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PLA2
-
Homo sapiens