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Literature summary for 3.1.1.4 extracted from

  • Hoffmann, G.E.; Schneider, E.; Brand, K.; Kozumplik, V.; Fateh-Moghadam, S.
    Characterization of a phospholipase A2 in human serum (1992), Eur. J. Clin. Chem. Clin. Biochem., 30, 111-117.
    View publication on PubMed
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
Tris/maleate buffer
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
14000
-
 heparin-sepharose affinity chromatography, SDS-PAGE after digestion with thrombin, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phospholipids + H2O Homo sapiens inflammatory diseases ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
gel filtration chromatography, more than 100fold Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.51
-
 substrate: standardized commercial phospholipid emulsion Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phospholipids + H2O inflammatory diseases Homo sapiens ?
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50
-
 highly susceptible to temperatures above 50°C under acidic and neutral conditions Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 with small additional optimum at pH 6 Homo sapiens