6.3.1.20: lipoate-protein ligase

This is an abbreviated version!
For detailed information about lipoate-protein ligase, go to the full flat file.

Word Map on EC 6.3.1.20

6.3.1.20

lipoylation

ligases

octanoyl-acyl

lipoate-dependent

apicoplast

octanoylation

2-oxoacids

lipoyl-amp

octanoic

bioorthogonal

lipoyltransferase

h-protein

octanoyltransferase

13-amino

biotechnology

synthesis

molecular biology

drug development

Reaction

a [lipoyl-carrier protein]-N6-(lipoyl)lysine

Synonyms

CTD, EC 2.7.7.63, LIP3, LipB, LipL1, lipoate ligase, lipoate ligase like protein, lipoate protein ligase, lipoate protein ligase B, lipoate-bound lipoate ligase 1, lipoate-protein ligase, lipoate-protein ligase A, lipoic acid ligase, lipoic acid ligase A, lipoic acid protein ligase, lipoic acid protein ligase A1, lipoyl ligase, lipoyl-protein ligase A, LPLA, LplA-LplB complex, LplA1, LplA1Ct, Lpla2, LplB, Oryza s. lipoate-protein ligase A, OsLPLA, PfLipL1

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.1 Acid—ammonia (or amine) ligases (amide synthases)

6.3.1.20 lipoate-protein ligase

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Results	in table
1	Activating Compound
10845	AA Sequence
5	Application
1	CAS Registry Number
14	Cloned(Commentary)
8	Cofactor
5	Crystallization (Commentary)
15	Disease/ Diagnostics
2	Expression
16	General Information
15	Inhibitors
4	kcat/KM [mM/s]
19	KM Value [mM]
10	Localization
18	Metals/Ions
13	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
43	Organism
1	Oxidation Stability
5	Pathway
2	PDB ID
4	pH Optimum
1	pH Range
2	pI Value
29	Protein Variants
11	Purification (Commentary)
4	Reaction
1	Reaction Type
35	Reference
1	Renatured (Commentary)
8	Source Tissue
5	Specific Activity [micromol/min/mg]
2	Storage Stability
71	Substrates and Products (Substrate)
8	Subunits
63	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
13	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 6.3.1.20 - lipoate-protein ligase

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11000

Thermoplasma acidophilum

Q9HKT1, Q9HKT2

SDS-PAGE, molecular weight of HisCTD fusion protein

703652

11200

Thermoplasma acidophilum

Q9HKT1

1 * 30800 + 1 * 11200, LplA-LplB complex, gel filtration

704515

30000

Arabidopsis thaliana

x * 30000, SDS-PAGE

737026

30800

Thermoplasma acidophilum

Q9HKT1

1 * 30800 + 1 * 11200, LplA-LplB complex, gel filtration

704515

32000

Thermoplasma acidophilum

Q9HKT1, Q9HKT2

SDS-PAGE, molecular weight of HisLplA fusion protein

703652

38000

2 entries

40000

Streptomyces coelicolor

x * 40000, SDS-PAGE

736496

41100

Thermoplasma acidophilum

Q9HKT1

LplA-LplB complex, gel filtration

41700

gel filtration

45000

47000

x * 47000, SDS-PAGE, both LPL-A and LPL-B

664920