6.3.1.20: lipoate-protein ligase

This is an abbreviated version!
For detailed information about lipoate-protein ligase, go to the full flat file.

Reaction

Synonyms

CTD, EC 2.7.7.63, LIP3, LipB, LipL1, lipoate ligase, lipoate ligase like protein, lipoate protein ligase, lipoate protein ligase B, lipoate-bound lipoate ligase 1, lipoate-protein ligase, lipoate-protein ligase A, lipoic acid ligase, lipoic acid ligase A, lipoic acid protein ligase, lipoic acid protein ligase A1, lipoyl ligase, lipoyl-protein ligase A, LPLA, LplA-LplB complex, LplA1, LplA1Ct, Lpla2, LplB, Oryza s. lipoate-protein ligase A, OsLPLA, PfLipL1

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.1 Acid—ammonia (or amine) ligases (amide synthases)

                6.3.1.20 lipoate-protein ligase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
10845	AA Sequence
5	Application
1	CAS Registry Number
14	Cloned(Commentary)
8	Cofactor
5	Crystallization (Commentary)
15	Disease/ Diagnostics
2	Expression
16	General Information
15	Inhibitors
4	kcat/KM [mM/s]
19	KM Value [mM]
10	Localization
18	Metals/Ions
13	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
43	Organism
1	Oxidation Stability
5	Pathway
2	PDB ID
4	pH Optimum
1	pH Range
2	pI Value
29	Protein Variants
11	Purification (Commentary)
4	Reaction
1	Reaction Type
35	Reference
1	Renatured (Commentary)
8	Source Tissue
5	Specific Activity [micromol/min/mg]
2	Storage Stability
71	Substrates and Products (Substrate)
8	Subunits
63	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
13	Turnover Number [1/s]

Application

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Application on EC 6.3.1.20 - lipoate-protein ligase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Application Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

biotechnology

Escherichia coli

P32099

the enzyme lipoic acid ligase (LplA) can be used for PRIME (probe incorporation mediated by enzymes) labeling, a rapid and specific fluorescent labeling method of the protein of interest by LplA

746424

drug development

Listeria monocytogenes

-

LplA1, but not LplA2, required for intracellular replication and/or virulence of Listeria monocytogenes

694219

molecular biology

Listeria monocytogenes

-

dependency of pathogen Listeria monocytogenes on LplA1 dictated by availability of host lipoyl substrates as alternative lipoate source

694219

synthesis

2 entries

synthesis

Escherichia coli

-

enzyme-mediated two-step labeling protocol suitable for live-cell labeling using lipoic acid ligase with norbornene substrates and subsequent inverse-electron demand Diels-Alder reaction

744699

synthesis

Escherichia coli

-

the enzyme can be used for a two-step labeling strategy that combines high selectivity of enzyme-mediated labeling with the chemoselectivity of palladium-catalyzed Sonogashira cross-coupling, overview

744447