3.4.24.B7: matrix metalloproteinase-26
This is an abbreviated version!
For detailed information about matrix metalloproteinase-26, go to the full flat file.
Word Map on EC 3.4.24.B7
-
3.4.24.B7
-
endometrial
-
timp-4
-
mmp-1
-
matrilysins
-
menstrual
-
medicine
-
pro-mmp-9
-
olomouc
-
metalloelastase
-
palacky
-
metalloproteinase-4
-
prodomain
-
diagnostics
-
synthesis
- 3.4.24.B7
- endometrial
- timp-4
- mmp-1
- matrilysins
-
menstrual
- medicine
- pro-mmp-9
-
olomouc
- metalloelastase
-
palacky
-
metalloproteinase-4
- prodomain
- diagnostics
- synthesis
Reaction
proteolytic degradation of proteins =
Synonyms
endometase, endometase/matrilysin-2, M10.029, matrilysin 2, matrilysin-2, matrilysis-2/MMP-26, matrix metalloproteinase-26, metalloproteinases-26, MMP-26, MMP-26/endometase/matrilysin-2, More
ECTree
Advanced search results
Metals Ions
Metals Ions on EC 3.4.24.B7 - matrix metalloproteinase-26
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ca2+
Zn2+
Ca2+
-
MMP-26 has one high-affinity and one low-affinity calcium binding site. High-affinity calcium binding is restored at physiologically low calcium conditions with a calcium-dissociation constant of 63 nM without inducing secondary and tertiary structural changes. Low-affinity calcium binding is restored at relatively high calcium concentrations and shows a low-affinity calcium-dissociation constant value of 0.12 mM, which is accompanied with the recovery of enzymatic activity reversibly and tertiary structural changes, but without secondary structural rearrangements
Zn2+
contains a zinc-binding site, coordination of zinc at the active site
Zn2+
-
zinc ion in the catalytic domain interacts with the conserved sequence PRCXXPD