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3.4.24.B7: matrix metalloproteinase-26

This is an abbreviated version!
For detailed information about matrix metalloproteinase-26, go to the full flat file.

Word Map on EC 3.4.24.B7

Reaction

proteolytic degradation of proteins =

Synonyms

endometase, endometase/matrilysin-2, M10.029, matrilysin 2, matrilysin-2, matrilysis-2/MMP-26, matrix metalloproteinase-26, metalloproteinases-26, MMP-26, MMP-26/endometase/matrilysin-2, More

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B7 matrix metalloproteinase-26

Reference

topprint

Reference on EC 3.4.24.B7 - matrix metalloproteinase-26

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Marchenko, G.N.; Ratnikov, B.I.; Rozanov, D.V.; Godzik, A.; Deryugina, E.I.; Strongin, A.Y.
Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin
Biochem. J.
356
705-718
2001
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Uria, J.A.; Lopez-Otin, C.
Matrilysin-2, a new matrix metalloproteinase expressed in human tumors and showing the minimal domain organization required for secretion, latency, and activity
Cancer Res.
60
4745-4751
2000
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Park, H.I.; Ni, J.; Gerkema, F.E.; Liu, D.; Belozerov, V.E.; Sang, Q.X.
Identification and characterization of human endometase (Matrix metalloproteinase-26) from endometrial tumor
J. Biol. Chem.
275
20540-20544
2000
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Marchenko, N.D.; Marchenko, G.N.; Strongin, A.Y.
Unconventional activation mechanisms of MMP-26, a human matrix metalloproteinase with a unique PHCGXXD cysteine-switch motif
J. Biol. Chem.
277
18967-18972
2002
Homo sapiens
Manually annotated by BRENDA team
Park, H.I.; Turk, B.E.; Gerkema, F.E.; Cantley, L.C.; Sang, Q.X.
Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26
J. Biol. Chem.
277
35168-35175
2002
Homo sapiens
Manually annotated by BRENDA team
Park, H.I.; Jin, Y.; Hurst, D.R.; Monroe, C.C.; Lee, S.; Schwartz, M.A.; Sang, Q.X.
The intermediate S1' pocket of the endometase/matrilysin-2 active site revealed by enzyme inhibition kinetic studies, protein sequence analyses, and homology modeling
J. Biol. Chem.
278
51646-51653
2003
Homo sapiens
Manually annotated by BRENDA team
Li, W.; Savinov, A.Y.; Rozanov, D.V.; Golubkov, V.S.; Hedayat, H.; Postnova, T.I.; Golubkova, N.V.; Linli, Y.; Krajewski, S.; Strongin, A.Y.
Matrix metalloproteinase-26 is associated with estrogen-dependent malignancies and targets alpha1-antitrypsin serpin
Cancer Res.
64
8657-8665
2004
Homo sapiens
Manually annotated by BRENDA team
Savinov, A.Y.; Remacle, A.G.; Golubkov, V.S.; Krajewska, M.; Kennedy, S.; Duffy, M.J.; Rozanov, D.V.; Krajewski, S.; Strongin, A.Y.
Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients
Cancer Res.
66
2716-2724
2006
Homo sapiens
Manually annotated by BRENDA team
Yamamoto, H.; Vinitketkumnuen, A.; Adachi, Y.; Taniguchi, H.; Hirata, T.; Miyamoto, N.; Nosho, K.; Imsumran, A.; Fujita, M.; Hosokawa, M.; Hinoda, Y.; Imai, K.
Association of matrilysin-2 (MMP-26) expression with tumor progression and activation of MMP-9 in esophageal squamous cell carcinoma
Carcinogenesis
25
2353-2360
2004
Homo sapiens
Manually annotated by BRENDA team
Marchenko, N.D.; Marchenko, G.N.; Weinreb, R.N.; Lindsey, J.D.; Kyshtoobayeva, A.; Crawford, H.C.; Strongin, A.Y.
beta-Catenin regulates the gene of MMP-26, a novel metalloproteinase expressed both in carcinomas and normal epithelial cells
Int. J. Biochem. Cell Biol.
36
942-956
2004
Homo sapiens
Manually annotated by BRENDA team
Ahokas, K.; Skoog, T.; Suomela, S.; Jeskanen, L.; Impola, U.; Isaka, K.; Saarialho-Kere, U.
Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis
J. Invest. Dermatol.
124
849-856
2005
Homo sapiens
Manually annotated by BRENDA team
Liu, G.; Zhang, X.; Lin, H.; Li, Q.; Wang, H.; Ni, J.; Amy Sang, Q.X.; Zhu, C.
Expression of matrix metalloproteinase-26 (MMP-26) mRNA in mouse uterus during the estrous cycle and early pregnancy
Life Sci.
77
3355-3365
2005
Mus musculus
Manually annotated by BRENDA team
Lee, S.; Park, H.I.; Sang, Q.X.
Calcium regulates tertiary structure and enzymatic activity of human endometase/matrilysin-2 and its role in promoting human breast cancer cell invasion
Biochem. J.
403
31-42
2007
Homo sapiens
Manually annotated by BRENDA team
Lee, S.; Desai, K.K.; Iczkowski, K.A.; Newcomer, R.G.; Wu, K.J.; Zhao, Y.; Tan, W.W.; Roycik, M.D.; Sang, Q.A.
Coordinated peak expression of MMP-26 and TIMP-4 in preinvasive human prostate tumor
Cell Res.
16
750-758
2006
Homo sapiens
Manually annotated by BRENDA team
Skoog, T.; Ahokas, K.; Orsmark, C.; Jeskanen, L.; Isaka, K.; Saarialho-Kere, U.
MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture
Exp. Dermatol.
15
775-783
2006
Homo sapiens
Manually annotated by BRENDA team
Pilka, R.; Oborna, I.; Lichnovsky, V.; Havelka, P.; Fingerova, H.; Eriksson, P.; Hansson, S.; Casslen, B.
Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patients
Hum. Reprod.
21
3146-3156
2006
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Mellanen, L.; Lahdevirta, J.; Tervahartiala, T.; Meurman, J.H.; Sorsa, T.
Matrix metalloproteinase-7, -8, -9, -25, and -26 and CD43, -45, and -68 cell-markers in HIV-infected patients saliva and gingival tissue
J. Oral Pathol. Med.
35
530-539
2006
Homo sapiens
Manually annotated by BRENDA team
Emingil, G.; Kuula, H.; Sorsa, T.; Atilla, G.
Gingival crevicular fluid matrix metalloproteinase-25 and -26 levels in periodontal disease
J. Periodontol.
77
664-671
2006
Homo sapiens
Manually annotated by BRENDA team
Bister, V.; Skoog, T.; Virolainen, S.; Kiviluoto, T.; Puolakkainen, P.; Saarialho-Kere, U.
Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma
Mod. Pathol.
20
1128-1140
2007
Homo sapiens
Manually annotated by BRENDA team
Ahokas, K.; Karjalainen-Lindsberg, M.L.; Sihvo, E.; Isaka, K.; Salo, J.; Saarialho-Kere, U.
Matrix metalloproteinases 21 and 26 are differentially expressed in esophageal squamous cell cancer
Tumour Biol.
27
133-141
2006
Homo sapiens
Manually annotated by BRENDA team
Park, H.I.; Lee, S.; Ullah, A.; Cao, Q.; Sang, Q.X.
Effects of detergents on catalytic activity of human endometase/matrilysin 2, a putative cancer biomarker
Anal. Biochem.
396
262-268
2010
Homo sapiens
Manually annotated by BRENDA team
Galewska, Z.; Romanowicz, L.; Jaworski, S.; Ba?kowski, E.
Matrix metalloproteinases, MMP-7 and MMP-26, in plasma and serum of control and preeclamptic umbilical cord blood
Eur. J. Obstet. Gynecol. Reprod. Biol.
150
152-156
2010
Homo sapiens
Manually annotated by BRENDA team
Souza Freitas, V.; Ferreira de Araujo, C.R.; Alves, P.M.; de Souza, L.B.; Galvao, H.C.; de Almeida Freitas, R.
Immunohistochemical expression of matrilysins (MMP-7 and MMP-26) in ameloblastomas and adenomatoid odontogenic tumors
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
108
417-424
2009
Homo sapiens
Manually annotated by BRENDA team
Zhao, Y.G.; Xiao, A.Z.; Ni, J.; Man, Y.G.; Sang, Q.X.
Expression of matrix metalloproteinase-26 in multiple human cancer tissues and smooth muscle cells
Ai Zheng
28
1168-1175
2009
Homo sapiens
Manually annotated by BRENDA team
Li, L.; Mei, T.H.; Zhou, X.D.; Zhang, X.G.
Expression and clinical significance of matrix metalloproteinase (MMP)-26 protein in non-small cell lung cancer
Ai Zheng
28
60-63
2009
Homo sapiens
Manually annotated by BRENDA team
Kuivanen, T.; Jeskanen, L.; Kylloenen, L.; Isaka, K.; Saarialho-Kere, U.
Matrix metalloproteinase-26 is present more frequently in squamous cell carcinomas of immunosuppressed compared with immunocompetent patients
J. Cutan. Pathol.
36
929-936
2009
Homo sapiens
Manually annotated by BRENDA team
Deng, Y.; Li, W.; Li, Y.; Yang, H.; Xu, H.; Liang, S.; Zhang, L.; Li, Y.
Expression of Matrix Metalloproteinase-26 promotes human glioma U251 cell invasion in vitro and in vivo
Oncol. Rep.
23
69-78
2010
Homo sapiens
Manually annotated by BRENDA team
Liu, J.; Cao, B.; Li, Y.; Wu, X.; Wang, Y.
GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts
Reprod. Biol. Endocrinol.
8
5
2010
Homo sapiens
Manually annotated by BRENDA team
Gruber, H.E.; Hoelscher, G.L.; Ingram, J.A.; Hanley, E.N.
Matrix metalloproteinase-26, a novel MMP, is constitutively expressed in the human intervertebral disc in vivo and in vitro
Exp. Mol. Pathol.
92
59-63
2011
Homo sapiens, Homo sapiens (Q9NRE1)
Manually annotated by BRENDA team
Zhang, Y.; Zhao, H.; Wang, Y.; Lin, Y.; Tan, Y.; Fang, X.; Zheng, L.
Non-small cell lung cancer invasion and metastasis promoted by MMP-26
Mol. Med. Rep.
4
1201-1209
2011
Homo sapiens
Manually annotated by BRENDA team
Almeida-Francia, C.C.; Keator, C.S.; Mah, K.; Holden, L.; Hergert, C.; Slayden, O.D.
Localization and hormonal regulation of endometrial matrix metalloproteinase-26 in the rhesus macaque
Hum. Reprod.
27
1723-1734
2012
Macaca mulatta (F6QMZ1), Macaca mulatta
Manually annotated by BRENDA team
Yang, H.; Wang, Y.; Li, Y.; Zhang, L.; Deng, Y.; Qi, D.; Li, Y.; Li, W.
Roles of matrix metalloproteinase-26 in the growth, invasion and angiogenesis of breast cancer
Oncol. Lett.
4
832-836
2012
Homo sapiens (Q9NRE1)
Manually annotated by BRENDA team
Mu, T.; Liang, W.; Ju, Y.; Wang, Z.; Wang, Z.; Roycik, M.D.; Sang, Q.X.; Yu, D.; Xiang, H.; Fang, X.
Efficient soluble expression of secreted matrix metalloproteinase 26 in Brevibacillus choshinensis
Protein Expr. Purif.
91
125-133
2013
Homo sapiens (Q9NRE1)
Manually annotated by BRENDA team
Xu, X.; Ma, J.; Li, C.; Zhao, W.; Xu, Y.
Regulation of chondrosarcoma invasion by MMP26
Tumour Biol.
36
365-369
2015
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Romanowicz, L.; Gogiel, T.; Galewska, Z.; Bruczko, M.; Baczyk, J.; Roszkowska-Jakimiec, W.; Sobolewski, K.
Divergent changes in the content and activity of MMP-26 and TIMP-4 in human umbilical cord tissues associated with preeclampsia
Eur. J. Obstet. Gynecol. Reprod. Biol.
231
48-53
2018
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Khamis, Z.I.; Iczkowski, K.A.; Man, Y.G.; Bou-Dargham, M.J.; Sang, Q.X.
Evidence for a proapoptotic role of matrix metalloproteinase-26 in human prostate cancer cells and tissues
J. Cancer
7
80-87
2016
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Guo, J.G.; Guo, C.C.; He, Z.Q.; Cai, X.Y.; Mou, Y.G.
High MMP-26 expression in glioma is correlated with poor clinical outcome of patients
Oncol. Lett.
16
2237-2242
2018
Homo sapiens (Q9NRE1), Homo sapiens
Manually annotated by BRENDA team
Zhang, G.; Zhang, J.; Li, X.; Meng, X.; Fang, X.
Identification of the endoplasmic reticulum localization sequence and N-glycosylation of matrix metalloproteinase 26
RSC Adv.
9
23053-23060
2019
Homo sapiens (Q9NRE1)
-
Manually annotated by BRENDA team