Cloned (Comment) | Organism |
---|---|
DNA sequence determination and analysis, expression of the zymogen in Escherichia coli | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc-binding motif VATHEIGHSLGLQH | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28000 | - |
x * 28000, recombinant zymogen, SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
proteins + H2O | Homo sapiens | enzyme might be rsponsible for inactivation of cytokins and serpins | peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NRE1 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | propeptides sequence PHCGVPDGSD | Homo sapiens |
Purification (Comment) | Organism |
---|---|
recombinant from Escherichia coli, to homogeneity | Homo sapiens |
Renatured (Comment) | Organism |
---|---|
recombinant zymogen from inclusion bodies expressed in Escherichia coli, partial activation of th proform during refolding | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endometrial adenocarcinoma cell | gene expression | Homo sapiens | - |
additional information | no expression in testis, heart, brain, lung, liver, thymus, and melanoma G361 cell | Homo sapiens | - |
uterus | gene expression | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(7-methoxycoumarin-4-yl)acetyl-PKPLAL-Dpa-AR-NH2 + H2O | synthetic fluorogenic peptide derived of matrix metalloproteinases | Homo sapiens | ? | - |
? | |
(7-methoxycoumarin-4-yl)acetyl-PLAQAV-Dpa-RSSSR-NH2 + H2O | synthetic fluorogenic peptide derived of tumor necrosis factor-alpha converting enzyme | Homo sapiens | ? | - |
? | |
(7-methoxycoumarin-4-yl)acetyl-PLGL-Dpa-AR-NH2 + H2O | synthetic fluorogenic peptide derived of matrix metalloproteinases | Homo sapiens | ? | - |
? | |
(7-methoxycoumarin-4-yl)acetyl-RPKPVE-norvaline-WMK-(2,4-dinitrophenyl)-NH2 + H2O | synthetic fluorogenic peptide derived of matrix metalloproteinases | Homo sapiens | ? | - |
? | |
(7-methoxycoumarin-4-yl)acetyl-RPKPYA-norvaline-WMK-(2,4-dinitrophenyl)-NH2 + H2O | synthetic fluorogenic peptide derived of matrix metalloproteinases | Homo sapiens | ? | - |
? | |
alpha1-proteinase inhibitor + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | no activity with collagens, laminin, elastin, beta-casein, plasminogen, soybean trypsin inhibitor, Bowman-Birk inhibitor | Homo sapiens | ? | - |
? | |
proteins + H2O | - |
Homo sapiens | peptides | - |
? | |
proteins + H2O | enzyme might be rsponsible for inactivation of cytokins and serpins | Homo sapiens | peptides | - |
? | |
type I gelatin + H2O | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 28000, recombinant zymogen, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
endometase | - |
Homo sapiens |
M10.029 | Merops-ID | Homo sapiens |
matrix metalloproteinase-26 | - |
Homo sapiens |
MMP-26 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |