3.4.24.B7: matrix metalloproteinase-26
This is an abbreviated version!
For detailed information about matrix metalloproteinase-26, go to the full flat file.
Word Map on EC 3.4.24.B7
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3.4.24.B7
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endometrial
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timp-4
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mmp-1
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matrilysins
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menstrual
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medicine
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pro-mmp-9
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olomouc
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metalloelastase
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palacky
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metalloproteinase-4
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prodomain
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diagnostics
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synthesis
- 3.4.24.B7
- endometrial
- timp-4
- mmp-1
- matrilysins
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menstrual
- medicine
- pro-mmp-9
-
olomouc
- metalloelastase
-
palacky
-
metalloproteinase-4
- prodomain
- diagnostics
- synthesis
Reaction
proteolytic degradation of proteins =
Synonyms
endometase, endometase/matrilysin-2, M10.029, matrilysin 2, matrilysin-2, matrilysis-2/MMP-26, matrix metalloproteinase-26, metalloproteinases-26, MMP-26, MMP-26/endometase/matrilysin-2, More
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Natural Substrates Products
Natural Substrates Products on EC 3.4.24.B7 - matrix metalloproteinase-26
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REACTION DIAGRAM
alpha1-antitrypsin + H2O
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MMP-26 by cleaving and inactivating the alpha1-antitrypsin serpin, operates as a unique functional link that regulates a coordinated interplay between Ser and metalloproteinases in estrogen-dependent neoplasm. Involvement of MMP-26 in inflammation and malignant progression of estrogen-dependent tumor
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additional information
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increased level and activation of MMP-26 in gingival crevicular fluid is associated with an enhanced severity of periodontal inflammation, suggesting that MMP-26 can participate in the progression of periodontal diseases
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pro-MMP-9 + H2O
MMP-9 + MMP-9 propeptide
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MMP-26 can activate MMP-9 by cleavage of some sites in pro-MMP-9
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proteins + H2O
peptides
enzyme might be rsponsible for inactivation of cytokins and serpins
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proteins + H2O
peptides
enzyme plays an important specific role in tumor progression and angiogenesis
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proteins + H2O
peptides
potentially implicated in tumor progression
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