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3.4.24.B7: matrix metalloproteinase-26

This is an abbreviated version!
For detailed information about matrix metalloproteinase-26, go to the full flat file.

Word Map on EC 3.4.24.B7

Reaction

proteolytic degradation of proteins =

Synonyms

endometase, endometase/matrilysin-2, M10.029, matrilysin 2, matrilysin-2, matrilysis-2/MMP-26, matrix metalloproteinase-26, metalloproteinases-26, MMP-26, MMP-26/endometase/matrilysin-2, More

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B7 matrix metalloproteinase-26

Natural Substrates Products

Natural Substrates Products on EC 3.4.24.B7 - matrix metalloproteinase-26

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
activated pro-MMP-9 + H2O
?
show the reaction diagram
-
-
-
?
alpha1-antitrypsin + H2O
?
show the reaction diagram
-
MMP-26 by cleaving and inactivating the alpha1-antitrypsin serpin, operates as a unique functional link that regulates a coordinated interplay between Ser and metalloproteinases in estrogen-dependent neoplasm. Involvement of MMP-26 in inflammation and malignant progression of estrogen-dependent tumor
-
-
?
denatured collagen type I + H2O
?
show the reaction diagram
-
-
-
?
denatured collagen type II + H2O
?
show the reaction diagram
-
-
-
?
denatured collagen type III + H2O
?
show the reaction diagram
-
-
-
?
denatured collagen type IV + H2O
?
show the reaction diagram
-
-
-
?
Fibrinogen + H2O
?
show the reaction diagram
-
-
-
?
Fibronectin + H2O
?
show the reaction diagram
Gelatin + H2O
?
show the reaction diagram
-
-
-
-
?
insulin-like growth factor binding protein 1 + H2O
?
show the reaction diagram
-
-
-
?
pro-MMP-9 + H2O
MMP-9 + MMP-9 propeptide
show the reaction diagram
proteins + H2O
peptides
show the reaction diagram
Type IV collagen + H2O
?
show the reaction diagram
vibronectin + H2O
?
show the reaction diagram
-
-
-
-
?
Vitronectin + H2O
?
show the reaction diagram
-
-
-
?
additional information
?
-
-
increased level and activation of MMP-26 in gingival crevicular fluid is associated with an enhanced severity of periodontal inflammation, suggesting that MMP-26 can participate in the progression of periodontal diseases
-
-
?