3.4.21.B6: prostasin

This is an abbreviated version!
For detailed information about prostasin, go to the full flat file.

Word Map on EC 3.4.21.B6

3.4.21.B6

matriptase

aldosterone

hai-1

furin

gpi-anchored

aprotinin

amiloride-sensitive

glycosylphosphatidylinositol-anchored

hepsin

nexin-1

kunitz-type

camostat

medicine

profilaggrin

enac-mediated

Reaction

endoprotease activity. Trypsin-like enzymatic activity =

Synonyms

CAP-1, CAP1, CAP1/PRSS8, channel activating protease 1, channel activating protease-1, channel-activating protease 1, channel-activating protease-1, LD47230p, prostasin, prostasin/PRSS8, PRSS8, S01.159, tracheal-prostasin

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.21 Serine endopeptidases

3.4.21.B6 prostasin

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Results	in table
17	Activating Compound
5	AA Sequence
13	Application
1	CAS Registry Number
21	Cloned(Commentary)
3	Crystallization (Commentary)
686	Disease/ Diagnostics
7	Expression
28	General Information
69	Inhibitors
36	Ki Value [mM]
18	KM Value [mM]
14	Localization
18	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
57	Organism
3	pH Optimum
1	pH Range
1	pI Value
6	Posttranslational Modification
10	Protein Variants
13	Purification (Commentary)
1	Reaction
6	Reaction Type
57	Reference
148	Source Tissue
44	Substrates and Products (Substrate)
5	Subunits
31	Synonyms
17	Turnover Number [1/s]

Purification

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Purification on EC 3.4.21.B6 - prostasin

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1960fold

by gel filtration

by sequential anion exchange and aprotinin affinity chromatography, by Ni-NTA His-bind chromatography

Homo sapiens

671251

DEAE Sepharose column chromatography, and hepatocyte growth factor activator inhibitor-1 mAb M19 immunoaffinity column chromatography

homogeneity

Ni-Sepharose column chromatography, HiTrap Q column chromatography, and Supderdex 200 gel filtration

Homo sapiens

709175

Ni-Sepharose column chromatography, HiTrap Q column chromatography, and Superdex 200 gel filtration

Homo sapiens

709175

standard method

2 entries